Protein supersaturation powers innate immunity and programmed cell deathAlejandro Rodriguez Gama1, Tayla Miller1, and Randal Halfmann1,2
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Evolution of networks in ancestral caspases that affect stability and allosteric regulation Clay Clark, Mithun Nag, Isha Joglekar, Melissa Fee, and David Diaz
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Molecular studies on Escherichia coli single-stranded DNA-binding protein (SSB)-associated complexes involved in bacterial survivalMeng-Hsuan Chen1, Shou-Yi Sheng1, Ching-Hao Teng2, and Shu-Ying Wang1
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Structural insight into the synergistic activities of NADase and SLO in the pathogenesis of Group A Streptococcus infectionShu-Ying Wang1, Wei-Jiun Tsai2, Michal Hammel3, and U-Ser Jeng4
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STRUCTURAL POLYMORPHISM OF Α-SYNUCLEIN AMYLOID FIBRILS IN PARKINSON'S DISEASEDan Li
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Biophysical study of the KlebC-TonB interactionQiaoyu Tian, Melissa Webby, Nicholson Housden, and Colin Kleanthous
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A comprehensive platform of highly-selective frizzled agonistsLevi Blazer, Jarrett Adams, and Sachdev Sidhu
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Mapping binding landscapes of Ras/effector interactions.Atílio Tomazini Júnior and Julia Shifman
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Structural basis for the specific interaction between scaffold protein PDZK1 and ion transporter URAT1Evgeny Mymrikov1,2, Christophe Wirth1, Jonas Heinicke1, Julian Goll1, Christoph Steck1, Julia Schimpf3, Anna Köttgen2,4, Thorsten Hugel2,3, and Carola Hunte1,2
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Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3Florian Becker1,2, Simon Fuchs1, Lukas Refisch3,4, Friedel Drepper5, Wolfgang Bildl6, Uwe Schulte6,7,9, Shuo Liang1, Jonas Heinicke1, Sierra Hansen 1, Clemens Kreutz3,7, Bettina Warscheid5,7,8, Bernd Fakler6,7,9, Evegeny Mymrikov1,7, and Carola Hunte1,7,9
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Cross-reactivity-aware T cell receptor-peptide specificity prediction enabled by positional scanning libraries Chad Brambley, George Gray, and Brian Baker
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Protein conformations and allosteric effects of the human mu-opioid receptor that lead to different activity profilesDavid Cooper and David Minh
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Conformations and Local Dynamics of the CopY Metal Sensor Revealed by EPR SpectroscopyMelanie Hirsch, Lukas Hofmann, Yulia Shenberger, Lada Gevorkyan-Airapetov, and Sharon Ruthstein
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Investigating the structure and dynamics of interleukin-2 towards novel Treg-biasing immunotherapy designClaire Woodward1,2, Shahlo Solieva1, Jinfa Ying3, Daniel Hwang2, Michael Young2, Adriaan Bax3, Gregory Bowman1, Viviane De Paula2, and Nikolaos Sgourakis1,2
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Local dynamics and structural characterization of the CsoR repressor in its DNA bound and unbound states: an EPR study. Yasmin Igbaria Jaber
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Following conformational changes in the intrinsically disorder extracellular domain of the full human copper transporter, hCtr1, as a function of Cu(I) binding.Shahaf Peleg
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Formation of purinosome in Mycobacterium smegmatisMatteo Dedola, Zdeněk Knejzlík, and Iva Pichová
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Structural insights into the epigenetic regulation of transcription factor Nkx6.1 by chromatin remodeling subunit BAF155 under normal and pathological conditionsLisa-Maria Weinhold1,2, Vanda Lux1, Magdalena Havlová1, and Václav Veverka1,2
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The Mechanism and Implications of Peptide Register Shifts in T Cell RecognitionTatiana Rosales
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PPIformer: Designing protein-protein interactions via 3D equivariant self-supervised learningAnton Bushuiev1, Petr Kouba1,2, Jiri Sedlar1, Jiri Damborsky2, Stanislav Mazurenko2, and Josef Sivic1
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Specificity and promiscuity of JAK recruitment regulates pleiotropy of cytokine-receptor signalingEyal Zoler1, Thomas Meyer2, Junel Sotolongo Bellón2, Boyue Sun1, Jacob Piehler1,2, and Gideon Schreiber1
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Dynamical allostery of multi-domain protein complexesJosef Sulc
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