7th International Conference on Molecular Perspectives on Protein-Protein Interactions

Authors List

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Author Abstracts
Pedebos Conrado Lipids Mediate Promiscuous Supramolecular Protein Assemblies in the Bacterial Outer Membrane
Adams Jarrett Synthetic antibodies targeting EPHA2 induce diverse signalling-competent clusters
A comprehensive platform of highly-selective frizzled agonists
How MHC proteins sample the antigenic universe to inform the immune system in human health and disease
Adriana-Lifshits Lucia A protocol for the design of peptidic PPI inhibitors integrating machine learning based generative peptide design, molecular docking and high-throughput binding assay screening
Arkin Michelle Stabilization of the 14-3-3/CRAF interaction for inhibition of the MAPK pathway
Baker Brian Cross-reactivity-aware T cell receptor-peptide specificity prediction enabled by positional scanning libraries
Bax Adriaan Investigating the structure and dynamics of interleukin-2 towards novel Treg-biasing immunotherapy design
Becker Florian Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Bellon Junel Specificity and promiscuity of members of the Janus Kinase family binding cytokine receptors, and its implications towards signaling
Specificity and promiscuity of JAK recruitment regulates pleiotropy of cytokine-receptor signaling
Bildl Wolfgang Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Blazer Levi A comprehensive platform of highly-selective frizzled agonists
Bogomolov Sergey Computational design and experimental optimization of PPI inhibitors from natural effectors
Bonadio Alessandro Computational design and experimental optimization of PPI inhibitors from natural effectors
BOSE Kakoli Non-canonical substrate recognition and processivity define the interaction between HtrA2 and its antiapoptotic binding partner Pea15
Bousova Kristyna Fusion of proteins is simple so the properties of the resulted proteins, or is it otherwise? How protein protein- interactions drive structure and properties of a multi-domain protein.
Bowman Gregory Investigating the structure and dynamics of interleukin-2 towards novel Treg-biasing immunotherapy design
Brambley Chad Cross-reactivity-aware T cell receptor-peptide specificity prediction enabled by positional scanning libraries
Brunsveld Luc Stabilization of the 14-3-3/CRAF interaction for inhibition of the MAPK pathway
Burg Elianne unravelling IRE1α interactions in the UPRosome
Bushuiev Anton PPIformer: Designing protein-protein interactions via 3D equivariant self-supervised learning
Call Melissa De novo-designed transmembrane domains tune chimeric antigen receptor function
Cambi Alessandra Mech(n)anoimmunology: podosome architecture and dynamics in 2D and 3D environments.
Chandler Nicholas De novo-designed transmembrane domains tune chimeric antigen receptor function
Chen Meng-Hsuan Molecular studies on Escherichia coli single-stranded DNA-binding protein (SSB)-associated complexes involved in bacterial survival
Choi Hyun-Kyu Catch bonds: Twenty years after their experimental demonstration
Cifuente Javier Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
Clark Clay Evolution of networks in ancestral caspases that affect stability and allosteric regulation
Cooper David Protein conformations and allosteric effects of the human mu-opioid receptor that lead to different activity profiles
Corzana Francisco Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
Damborsky Jiri PPIformer: Designing protein-protein interactions via 3D equivariant self-supervised learning
Danilowicz Claudia How RecA nucleoprotein filaments respond to internal mechanical stress: a molecular dynamics simulation study
Davey Ashleigh De novo-designed transmembrane domains tune chimeric antigen receptor function
De Paula Viviane Investigating the structure and dynamics of interleukin-2 towards novel Treg-biasing immunotherapy design
De Puysseleyr Veronic unravelling IRE1α interactions in the UPRosome
Dedola Matteo Formation of purinosome in Mycobacterium smegmatis
Deredge Daniel Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
Diaz David Evolution of networks in ancestral caspases that affect stability and allosteric regulation
Drepper Friedel Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Du Jonathan Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
Dutta Shubhankar Non-canonical substrate recognition and processivity define the interaction between HtrA2 and its antiapoptotic binding partner Pea15
Elazar Assaf De novo-designed transmembrane domains tune chimeric antigen receptor function
Fakler Bernd Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Fee Melissa Evolution of networks in ancestral caspases that affect stability and allosteric regulation
Fleishman Sarel De novo-designed transmembrane domains tune chimeric antigen receptor function
Fuchs Simon Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Gabay Matan A protocol for the design of peptidic PPI inhibitors integrating machine learning based generative peptide design, molecular docking and high-throughput binding assay screening
Gal Maayan A protocol for the design of peptidic PPI inhibitors integrating machine learning based generative peptide design, molecular docking and high-throughput binding assay screening
Garcia-Parajo Maria High-density single molecule maps to resolve transient multi-molecular receptor interactions in living cells.
Gerlo Sarah unravelling IRE1α interactions in the UPRosome
Gevorkyan-Airapetov Lada Conformations and Local Dynamics of the CopY Metal Sensor Revealed by EPR Spectroscopy
Goll Julian Structural basis for the specific interaction between scaffold protein PDZK1 and ion transporter URAT1
Gras Stephanie Host genetics is linked with asymptomatic profile of COVID-19
Gray George Cross-reactivity-aware T cell receptor-peptide specificity prediction enabled by positional scanning libraries
Guerin Marcelo Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
Halfmann Randal Protein supersaturation powers innate immunity and programmed cell death
Pathologic polyglutamine aggregation begins with a self-poisoning polymer crystal
Hammel Michal Structural insight into the synergistic activities of NADase and SLO in the pathogenesis of Group A Streptococcus infection
Hansen Sierra Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Havlová Magdalena Structural insights into the epigenetic regulation of transcription factor Nkx6.1 by chromatin remodeling subunit BAF155 under normal and pathological conditions
Heinicke Jonas Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Structural basis for the specific interaction between scaffold protein PDZK1 and ion transporter URAT1
Hirsch Melanie Conformations and Local Dynamics of the CopY Metal Sensor Revealed by EPR Spectroscopy
Hofmann Lukas Conformations and Local Dynamics of the CopY Metal Sensor Revealed by EPR Spectroscopy
Housden Nicholson Biophysical study of the KlebC-TonB interaction
Hugel Thorsten Structural basis for the specific interaction between scaffold protein PDZK1 and ion transporter URAT1
Hunte Carola Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Structural basis for the specific interaction between scaffold protein PDZK1 and ion transporter URAT1
Hwang Daniel Investigating the structure and dynamics of interleukin-2 towards novel Treg-biasing immunotherapy design
Igbaria Jaber Yasmin Local dynamics and structural characterization of the CsoR repressor in its DNA bound and unbound states: an EPR study.
Inns Patrick Lipids Mediate Promiscuous Supramolecular Protein Assemblies in the Bacterial Outer Membrane
Jeng U-Ser Structural insight into the synergistic activities of NADase and SLO in the pathogenesis of Group A Streptococcus infection
Joglekar Isha Evolution of networks in ancestral caspases that affect stability and allosteric regulation
Kandola Tejbir Pathologic polyglutamine aggregation begins with a self-poisoning polymer crystal
Keating Amy A tale of two EVH1 domains
Kenanova Dyana Stabilization of the 14-3-3/CRAF interaction for inhibition of the MAPK pathway
Khalid Syma Lipids Mediate Promiscuous Supramolecular Protein Assemblies in the Bacterial Outer Membrane
Kleanthous Colin Biophysical study of the KlebC-TonB interaction
Powered PPIs: How bacteria use energised protein-protein interactions to coordinate outer membrane constriction with cell division
Lipids Mediate Promiscuous Supramolecular Protein Assemblies in the Bacterial Outer Membrane
Klontz Erik Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
Knejzlík Zdeněk Formation of purinosome in Mycobacterium smegmatis
Kobe Bostjan Open-ended signalling assemblies formed by TIR domains
Koide Shohei Creating protein-protein interactions
Konstantinidou Markella Stabilization of the 14-3-3/CRAF interaction for inhibition of the MAPK pathway
Kosloff Mickey Structural elements in Gα proteins integrate multi-specific partner interactions and inactivation
Köttgen Anna Structural basis for the specific interaction between scaffold protein PDZK1 and ion transporter URAT1
Kouba Petr PPIformer: Designing protein-protein interactions via 3D equivariant self-supervised learning
Kragelund Birthe B. Order and disorder in protein complexes
Kreutz Clemens Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Landry Christian Non-adaptive processes contribute to the organization of cellular networks.
Lemmens Irma unravelling IRE1α interactions in the UPRosome
Leroy Kaat unravelling IRE1α interactions in the UPRosome
Li Dan STRUCTURAL POLYMORPHISM OF Α-SYNUCLEIN AMYLOID FIBRILS IN PARKINSON'S DISEASE
Liang Shuo Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Lidke Diane Nanoscale imaging of the FcεRI signalosome
Adaptive Smart Microscopy for Quantitative Imaging of Protein-Protein Interactions
Liu Cong Mechanistic view of α-synuclein pathological aggregation in Parkinson's disease
Lux Vanda Structural insights into the epigenetic regulation of transcription factor Nkx6.1 by chromatin remodeling subunit BAF155 under normal and pathological conditions
Mallagaray Alvaro Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
Manzo Carlo High-density single molecule maps to resolve transient multi-molecular receptor interactions in living cells.
Mateos Nicolas High-density single molecule maps to resolve transient multi-molecular receptor interactions in living cells.
Mayor Satyajit High-density single molecule maps to resolve transient multi-molecular receptor interactions in living cells.
Mazurenko Stanislav PPIformer: Designing protein-protein interactions via 3D equivariant self-supervised learning
Meyer Thomas Specificity and promiscuity of members of the Janus Kinase family binding cytokine receptors, and its implications towards signaling
Specificity and promiscuity of JAK recruitment regulates pleiotropy of cytokine-receptor signaling
Miller Tayla Protein supersaturation powers innate immunity and programmed cell death
Minh David Protein conformations and allosteric effects of the human mu-opioid receptor that lead to different activity profiles
Mohammed Shabaz Lipids Mediate Promiscuous Supramolecular Protein Assemblies in the Bacterial Outer Membrane
Moiseenkova-Bell Vera Structural Pharmacology of TRPV channels
Mymrikov Evegeny Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Structural basis for the specific interaction between scaffold protein PDZK1 and ion transporter URAT1
Nag Mithun Evolution of networks in ancestral caspases that affect stability and allosteric regulation
Nagy Peter Effect of the plasma membrane on local ligand concentration
Natu Kalyani Non-canonical substrate recognition and processivity define the interaction between HtrA2 and its antiapoptotic binding partner Pea15
Nissan Michael A protocol for the design of peptidic PPI inhibitors integrating machine learning based generative peptide design, molecular docking and high-throughput binding assay screening
Olerinyova Anna Lipids Mediate Promiscuous Supramolecular Protein Assemblies in the Bacterial Outer Membrane
Oluwole Abraham Lipids Mediate Promiscuous Supramolecular Protein Assemblies in the Bacterial Outer Membrane
Ottmann Christian Stabilization of the 14-3-3/CRAF interaction for inhibition of the MAPK pathway
Parui Aasna Non-canonical substrate recognition and processivity define the interaction between HtrA2 and its antiapoptotic binding partner Pea15
Peleg Shahaf Following conformational changes in the intrinsically disorder extracellular domain of the full human copper transporter, hCtr1, as a function of Cu(I) binding.
Pennings Marloes Stabilization of the 14-3-3/CRAF interaction for inhibition of the MAPK pathway
Pichová Iva Formation of purinosome in Mycobacterium smegmatis
Piehler Jacob Specificity and promiscuity of members of the Janus Kinase family binding cytokine receptors, and its implications towards signaling
Assembly and dynamics of cytokine receptor signaling complexes in the plasma membrane
Specificity and promiscuity of JAK recruitment regulates pleiotropy of cytokine-receptor signaling
Prakaash Dheeraj Lipids Mediate Promiscuous Supramolecular Protein Assemblies in the Bacterial Outer Membrane
Prentiss Mara How RecA nucleoprotein filaments respond to internal mechanical stress: a molecular dynamics simulation study
Prévost Chantal How RecA nucleoprotein filaments respond to internal mechanical stress: a molecular dynamics simulation study
Puja Rashmi Non-canonical substrate recognition and processivity define the interaction between HtrA2 and its antiapoptotic binding partner Pea15
Raeeszadeh Sarmazdeh Maryam Engineering minimal TIMP-based inhibitors using DNA shuffling and yeast display
Rauscher Sarah Understanding Protein Motion and Protein Disorder Using All-Atom Simulation
Refisch Lukas Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Rodriguez Gama Alejandro Protein supersaturation powers innate immunity and programmed cell death
Rogier Tess unravelling IRE1α interactions in the UPRosome
Rosales Tatiana The Mechanism and Implications of Peptide Register Shifts in T Cell Recognition
Rudolph Lorena Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
Ruthstein Sharon Conformations and Local Dynamics of the CopY Metal Sensor Revealed by EPR Spectroscopy
Sabei Afra How RecA nucleoprotein filaments respond to internal mechanical stress: a molecular dynamics simulation study
Sagui Celeste Pathologic polyglutamine aggregation begins with a self-poisoning polymer crystal
Schimpf Julia Structural basis for the specific interaction between scaffold protein PDZK1 and ion transporter URAT1
Schreiber Gideon Specificity and promiscuity of members of the Janus Kinase family binding cytokine receptors, and its implications towards signaling
Specificity and promiscuity of JAK recruitment regulates pleiotropy of cytokine-receptor signaling
SARS-CoV-2 evolution is driven by parallel forces altering the sequence of the Spike-ACE2 protein-protein interaction
Schulte Uwe Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Sedlar Jiri PPIformer: Designing protein-protein interactions via 3D equivariant self-supervised learning
Sgourakis Nikolaos Understanding chaperone interactions with HLA molecules through the lens of molecular evolution and protein engineering
Investigating the structure and dynamics of interleukin-2 towards novel Treg-biasing immunotherapy design
Shenberger Yulia Conformations and Local Dynamics of the CopY Metal Sensor Revealed by EPR Spectroscopy
Sheng Shou-Yi Molecular studies on Escherichia coli single-stranded DNA-binding protein (SSB)-associated complexes involved in bacterial survival
Sher Inbal A protocol for the design of peptidic PPI inhibitors integrating machine learning based generative peptide design, molecular docking and high-throughput binding assay screening
Shifman Julia Computational design and experimental optimization of PPI inhibitors from natural effectors
Mapping binding landscapes of Ras/effector interactions.
Shirian Jason Computational design and experimental optimization of PPI inhibitors from natural effectors
Sidhu Sachdev Synthetic antibodies targeting EPHA2 induce diverse signalling-competent clusters
A comprehensive platform of highly-selective frizzled agonists
Sil Parijat High-density single molecule maps to resolve transient multi-molecular receptor interactions in living cells.
Sips Patrick unravelling IRE1α interactions in the UPRosome
Sivic Josef PPIformer: Designing protein-protein interactions via 3D equivariant self-supervised learning
Sohn Jungsan Signaling and regulation mechanisms of the AIM2-ASC Inflammasome.
Solieva Shahlo Investigating the structure and dynamics of interleukin-2 towards novel Treg-biasing immunotherapy design
Sova Marina A protocol for the design of peptidic PPI inhibitors integrating machine learning based generative peptide design, molecular docking and high-throughput binding assay screening
Spangler Jamie De novo engineering of cytokine/receptor interactions to study and manipulate the immune response
Springer Timothy The soul of the integrin machine
Steck Christoph Structural basis for the specific interaction between scaffold protein PDZK1 and ion transporter URAT1
Sulc Josef Dynamical allostery of multi-domain protein complexes
Sun Boyue Specificity and promiscuity of members of the Janus Kinase family binding cytokine receptors, and its implications towards signaling
Specificity and promiscuity of JAK recruitment regulates pleiotropy of cytokine-receptor signaling
Sundberg Eric Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
Szabó Ágnes Effect of the plasma membrane on local ligand concentration
Szatmári Tímea Effect of the plasma membrane on local ligand concentration
Tavernier Jan unravelling IRE1α interactions in the UPRosome
Teng Ching-Hao Molecular studies on Escherichia coli single-stranded DNA-binding protein (SSB)-associated complexes involved in bacterial survival
Tian Qiaoyu Biophysical study of the KlebC-TonB interaction
Tomazini Júnior Atílio Mapping binding landscapes of Ras/effector interactions.
Torreno-Pina Juan High-density single molecule maps to resolve transient multi-molecular receptor interactions in living cells.
Trastoy Beatriz Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
Tripsianes Konstantinos Fusion of proteins is simple so the properties of the resulted proteins, or is it otherwise? How protein protein- interactions drive structure and properties of a multi-domain protein.
Tsai Wei-Jiun Structural insight into the synergistic activities of NADase and SLO in the pathogenesis of Group A Streptococcus infection
Tubiana Jerome A protocol for the design of peptidic PPI inhibitors integrating machine learning based generative peptide design, molecular docking and high-throughput binding assay screening
van den Oetelaar Maxime Stabilization of the 14-3-3/CRAF interaction for inhibition of the MAPK pathway
Venkatesan Shriram Pathologic polyglutamine aggregation begins with a self-poisoning polymer crystal
Veverka Václav Structural insights into the epigenetic regulation of transcription factor Nkx6.1 by chromatin remodeling subunit BAF155 under normal and pathological conditions
Vickery Holly Stabilization of the 14-3-3/CRAF interaction for inhibition of the MAPK pathway
Virta Johanna Stabilization of the 14-3-3/CRAF interaction for inhibition of the MAPK pathway
Visser Emira Stabilization of the 14-3-3/CRAF interaction for inhibition of the MAPK pathway
Vondrasek Jiri Fusion of proteins is simple so the properties of the resulted proteins, or is it otherwise? How protein protein- interactions drive structure and properties of a multi-domain protein.
Wang Shu-Ying Molecular studies on Escherichia coli single-stranded DNA-binding protein (SSB)-associated complexes involved in bacterial survival
Structural insight into the synergistic activities of NADase and SLO in the pathogenesis of Group A Streptococcus infection
Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
Warscheid Bettina Target-myristoyl switch and conformational regulation of calcineurin B homologous protein 3
Webby Melissa Biophysical study of the KlebC-TonB interaction
Lipids Mediate Promiscuous Supramolecular Protein Assemblies in the Bacterial Outer Membrane
Weinhold Lisa-Maria Structural insights into the epigenetic regulation of transcription factor Nkx6.1 by chromatin remodeling subunit BAF155 under normal and pathological conditions
Wirth Christophe Structural basis for the specific interaction between scaffold protein PDZK1 and ion transporter URAT1
Wolfson Haim A protocol for the design of peptidic PPI inhibitors integrating machine learning based generative peptide design, molecular docking and high-throughput binding assay screening
Woodward Claire Investigating the structure and dynamics of interleukin-2 towards novel Treg-biasing immunotherapy design
Ying Jinfa Investigating the structure and dynamics of interleukin-2 towards novel Treg-biasing immunotherapy design
Young Michael Investigating the structure and dynamics of interleukin-2 towards novel Treg-biasing immunotherapy design
Zahradnik Jiri SARS-CoV-2 evolution is driven by parallel forces altering the sequence of the Spike-ACE2 protein-protein interaction
Zhang Jiahui Pathologic polyglutamine aggregation begins with a self-poisoning polymer crystal
Zhu Cheng Catch bonds: Twenty years after their experimental demonstration
Zoler Eyal Specificity and promiscuity of members of the Janus Kinase family binding cytokine receptors, and its implications towards signaling
Specificity and promiscuity of JAK recruitment regulates pleiotropy of cytokine-receptor signaling