8th International Conference on Molecular Perspectives in Protein-Protein Interactions

Posters

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38 In situ protein dynamics: insights from Cryo-Electron Tomography
Itziar Serna Martin
39 A Modular Toolkit for Nanoscale Interrogation of Multiprotein Assemblies Inside Living Cells
Arthur Felker, Michael Philippi, Michael Holtmannspötter, Christoph Drees, Evelin Schäfer, Martin Steinhart, Rainer Kurre, Changjiang You, and Jacob Piehler
40 Discovery of intracellular protein-protein interaction peptide modulators based on machine-learning and biophysical tools and their biotechnological applications
Lucia Adriana Lifshits1, Matan Gabay1, Marina Sova1, Jerome Tubiana2, and Maayan Gal1
41 Real-time visualization of STAT activation in live cells using genetically-encoded biosensors
Roman Meledin
42 Directed exploration of protein interaction sequence space reveals the role of binding availability for interaction strength
Pascale Lemieux, Alexandre K Dubé, and Christian R Landry
43 Engineering a Bifunctional IL-10/CTLA-4 Fusion Protein for Enhanced Immune Modulation in Autoimmune Disease
Maayan Gal3, Itamar Yadid2,, Matan Gabay3, and Omry Cohen2,
44 Design of binders to the oncogenic Ras mutant
Sergei Bogomolov, Atilio Junior Tomazini, and Julia Shifman
45 Dynamic multivalency tunes the tau–tubulin protein–protein interaction: insights from coarse-grained simulations and machine learning
Segev Naveh Tassa
46 Quantifying protein-protein interactions in G protein signaling using BRET sensors
Irina Nekrasova1, Isra Sadiya1, Meirav Avital-Shacham1, Christian LeGouill2, Michel Bouvier2, and Mickey Kosloff1
47 Multispecific Targeting of CD44 and catalytic and hemopexin Domains of MMP9 as a therapeutic Strategy for Osteoclast Inhibition in Osteoporosis
Dan Pasternak and Niv Papo
48 Predicting Affinity and Epistasis of Chymotrypsin–BPTI Mutant Interaction
Noam Tzuri1,2, Yaron Orenstein3,4, and Niv Papo1,2
49 Structure-based design of tunable mini-Gαs molecular switches
Lyudmila M Getmanenko, Sabreen Higazy Mreih, Irina Nekrasova, Meirav Avital Shacham, and Mickey Kosloff
50 Molecular determinants of the high-affinity binding of URAT1 transporter to PDZK1 scaffold protein
Evgeny V. Mymrikov1,2, Christophe Wirth1, Jonas Immanuel Heinicke1, Julian Goll1, Bianca Kern1, Christoph Steck1, Anastasiia K. Iaroslavtceva1, Julia Schimpf3, Anna Köttgen2,5, Thorsten Hugel2,3, and Carola Hunte1,2,4
51 Studying the interaction of Gα subunits with downstream effectors using synthetic “mini-G” proteins
Rojeh Ehab Eid
52 Decoding MuSK Pathways in Neuromuscular Junction Formation using Proximity Labeling
Cinzia Barresi1, Ruth Herbst1, Weiqiang Chen2, and Markus Hartl2
53 Ultrastructural organization and dynamics of the lysosomal HOPS tethering complex on membranes
Kevin Tanzusch1,2, Eduard Haar1,2, Arthur Felker1,2, Nadia Füllbrunn1, Michael Holtmannspötter1,2, Rainer Kurre1,2, Lars Langemeyer1, Changjiang You1,2, Christian Ungermann1,2, and Jacob Piehler1,2
54 Multiple signaling roles of CD3 ITAMs and its biological function in T cells
Yumeng Zhang
55 A third-generation proteome-wide interaction map of Helicobacter pylori based on tiled synthetic fragments and next-generation sequencing
Joel Malek
56 Unlocking Protein-RNA Interactions: Time-Resolved Serial Crystallography of Ribosome-IF1 as a Paradigm
Ilkin Yapici and Hasan DeMirci
57 Variable new antigen receptors from sharks engage epitopes inaccessible to conventional antibodies on fibroblast activation protein
Aaron LeBeau1, Timothy Grant1, Eric Lake1, Kendahl Ott1, and Roma Broadberry2
58 Efficient prediction of core binding sites in proteins through compact surface encoding and machine learning
Greta Grassmann1,, Lorenzo Di Rienzo, Giancarlo Ruocco1,, Mattia Miotto1, and Edoardo Milanetti1,
59 Unmasking Ectodomain Shedding Defects: The ADAM10/17 Proxy Proteome in Inflammation and Neovascularization
Jayantha Gunaratne, Zijie Lim, Sammi Wong, and Jia Yee Wu