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41 |
Molecular and genetic mechanisms of dermal matrix remodeling in the pathogenesis of severe acne Olga M. Demina
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42 |
Hyperglycemia promotes a pro-inflammatory neutrophil phenotypeSophia Reidel, Rianne Nederlof, Andrè Spychala, and Axel Gödecke
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43 |
The role of cellular metabolic pathways in the pathogenesis of psoriasisTim Sparwasser
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44 |
Investigating the role of NMES1 as a modulator of innate immune responsesJulia Kamper and Veit Hornung
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45 |
Renal cell carcinoma: does the obesity paradox extend to this obesity–associated tumor?Rachel J. Perry
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Histone Lysine Demethysale 6B (KMD6B) maintains adipose tissue integrity and function by reprogramming perivascular adipose tissue macrophages upon energy surplusZaineb Mezdari1, Dina Chokr1, Raphaëlle Ballaire1, Marc Diedisheim1, Jean-Baptiste Julla1,2, Fawaz Alzaid1, Camille Bleriot1,3, Florent Ginhoux3, Elise Dalmas1, and Nicolas Venteclef1
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Red blood cells as immune and metabolic modulators – impact on neutrophil activity in homeostasis and systemic inflammationAnna Such and Elzbieta Kolaczkowska
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48 |
Itaconate inhibits formation of neutrophil extracellular traps (NETs) independently of the age and metabolic state of miceGabriela Burczyk and Elzbieta Kolaczkowska
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plasma cell differentiation relies on a transporter that supports B cell metabolism by regulating intracellular pHAnthony Tao1, Kurt Hu2, and Stefan Feske1
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50 |
Role of tRNA fragments in islet macrophage activation and in the crosstalk with β-cells during obesityCristina Cosentino1, Alessandra Galli3, Flora Brozzi1, Shagun Poddar1, Veronique Menoud1, Guay Claudiane1, Cecile Jacovetti1, and Romano Regazzi1,3
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51 |
Rapamycin treatment following clearance of the influenza virus alters persistent inflammation in the lungBrydie R Huckestein2, Kelly Zeng3, and John F Alcorn1
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Obesity impacts the function, transcriptional regulation, and immunometabolism of natural killer cells during influenza infectionPamela H Brigleb1, Theresa Bub1,2, Brandi Livingston1, Bridgett Sharp1, and Stacey Schultz-Cherry1
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53 |
Reversible expansion of tissue macrophage populations in response to macrophage colony-stimulating factor (CSF1) administration transforms systemic metabolism to fuel growthSahar Keshvari, Katharine M Irvine, and David A Hume
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54 |
Infiltration of monocyte-derived macrophages perturbs the CNS metabolic landscape, licencing arginine catabolism and augments neuro-inflammationAndrea Vogel 4, Martina Kerndl1, Andrea Komljenovic1, Tobias Bausbacher2, James Lucas Cairns2, Christian Riedl 5, Roko Sangor3, Laszlo Musiejovsky1, Ana Korosec1, Melanie Hofmann1, Markus Kieler1, Simon Hametner5, Thomas Rattei3, Carsten Hopf2, Ryan Sheldon6, Omar Sharif1, and Gernot Schabbauer1
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Innate immune stimulation regulates glycolysis by PFKL phosphorylation Meiyue Wang1, Veit Hornung1, Thomas Fröhlich1, Heinrich Flaswinkel2, Benedikt Wefers3, and Abhinav Joshi4
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56 |
Septum associated macrophages control adipocyte stem cell fate and adipose tissue expansionSvetoslav Chakarov1,2, Hwee Ying Lim3,4, Ziyi Li1, Diego Adhemar Jaitin5, Jing Tian1, Katharine Yang2, Wan Ting Kong2,6, David Alejandro Bejarano7, Mathilde Bied6, Lucie Orliaguet8, Gowshika Rengasamy2, Zachary Chow2,9, Christopher Zhe Wei Lee2, Josephine Lum2, Xiaomeng Zhang2, Jinmiao Chen2, Peter See2, Benoit Malleret2,3, Sonia Baig10, Muhammad Shabeer10, Sue-Anne Ee Shiow Toh10, Bernard Malissen11,12, Kenji Kabashima2,9,13, Lai Guan Ng2, Camille Bleriot2,6,8, Zhaoyuan Liu1, Xiujun Fu14, Nicolas Venteclef8, Bing Su1, Ido Amit5, Andreas Schlitzer7, Veronique Angeli3,4, and Florent Ginhoux1,2,6,15
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57 |
Targeting glutaminolysis pathway in trained immunity induced by oxidized low-density lipoproteinAlice Scarpa, Laszlo Groh2, Katarzyna Placek, Mihai Netea, Siroon Bekkering2, and Niels Riksen2
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58 |
CaN-NFAT controls immunometabolic reprogramming of human monocytes and contributes to immunoparalysis in sepsisMarcela Hortova-Kohoutkova and Jan Frič
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59 |
Altered mitochondrial features may contribute to impeded M1 polarization of macrophages by sulforaphaneSheyda Bahiraii and Elke H heiss
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60 |
Functional profiling of cardiolipin deficient regulatory T cellsAnnamaria Regina and Mauro Corrado
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61 |
Metabolic rewiring mechanisms and vulnerabilities in cardiolipin deficient T cells Sara Gjurgji and Mauro Corrado
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62 |
Autophagy modulation is impaired in diabetic stem cell mobilopathyFrancesco Ivan Amendolagine1,3, Mattia Albiero2,3, Carolotta Boscaro2,3, Anna Rodella1,3, Ludovica Migliozzi1,3, and Gian Paolo Fadini2,3
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63 |
single-cell lipidomics reveal different metabolic reprogramming between activated CD4+ T cells and in vitro induced regulatory T cellsNastassia Robert, Luisa Abreu, and Theodore Alexandrov
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64 |
Reprogramming the metabolic state of induced pluripotent stem cell- derived T cells Alexandros Nianias1, Cindy JM van Velzen1, Ratchapong Netsrithong1, Thomas Baardemans1, Helga Simon-Molas2, Jaco AC van Bruggen2, Richard WJ Groen1, Tuna Mutis1, Arnon P Kater2, and Maria Themeli1
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65 |
Glutathione supports lipid abundance in vivoGloria Asantewaa
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66 |
The alarmins S100A8 and S100A9 facilitate experimental adaptive thermogenesisRoni Tron, Inbar Shteinberg, Anat Neumann, Nimrod Levy, Chen Varol, Isabel Zvibel, and Sigal Fishman
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67 |
Mitochondrial oxidative stress shapes regulatory T cell fate in the tumor microenvironment to restrain antitumor immune responses.Dimitra Kerdidani1, Dimitra Spyropoulou1, Anestis Makris1, Panagiotis Verginis2, and Themis Alissafi1,3
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68 |
Itaconate derivatives modulate Secretory leukocyte protease inhibitor production in macrophagesEwa Oleszycka1, Natalia Pocałuń1, Kamila Kwiecień1, Anna Grochot-Przęczek2, and Joanna Cichy1
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69 |
COMMD10 in macrophages and hepatocytes plays discrepant roles in metabolizing lipids during NASHBander Abu Shrkihe1, Shani Ben-Shlomo-Zidovetsky1, Nathan Gluck1, and Chen Varol1,2
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70 |
Relative hypoglycemia induced by strong infection enhances innate anti-viral immune control and is defective in diabetesSanja Mikašinović1, Marko Šestan1, Ante Benić1, Christoforos Dimitropoulos2, Mia Krapić1, Lea Hiršl3, Đurđica Cekinović Grbeša4, Tamara Turk Wensveen5,6, Marina Babić1,2, Stephan Wueest7, Daniel Konrad7, Felix Martinus Wensveen1, and Bojan Polić1
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71 |
Epigenomic and Metabolic Rewiring of Blood Monocytes Influence the Risk of Cardiovascular Events in People with Type 2 Diabetes
Nicolas Venteclef
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72 |
β-glucan modulates HSPCs mobilization through Osm downregulation in macrophagesCarlotta Boscaro1,2, Francesco Ivan Amendolagine1,2, Anna Rodella1,2, Ludovica Migliozzi1,2, Gian Paolo Fadini1,2, and Mattia Albiero1,2
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73 |
Cell-specific origin of Oncostatin M and regulation of hematopoietic stem/progenitor cell trafficAnna Rodella1,3, Mattia Albiero2,3, Carlotta Boscaro2,3, Ludovica Migliozzi2,3, Francesco Ivan Amendolagine1,3, and Gian Paolo Fadini2,3
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74 |
NETosis as mediator of the metabolic effects of high-fat diet modified microbiota
Ludovica Migliozzi1,2, Mattia Albiero1,2, Francesco Ivan Amendolagine1,3, Carlotta Boscaro1,2, Anna Rodella1,3, and Gian Paolo Fadini1,2
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Metabolic Rewiring shapes Dendritic Cell Autoimmune Disease Promoting FunctionNikos E. Papaioannou1,2, Georgia Kontogianni1,2, Dimitra Kerdidani1,2, Rafael J. Argüello3, and Themis Alissafi1,2
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76 |
Glucocorticoids shape macrophage response to diet-induced liver cancerUlrich Stifel1, Tim Schaffranek1, Jan Tuckermann1, and Giorgio Caratti1,2
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77 |
Th17 cell-intrinsic ROS-scavenging-IL22 axis protects against intestinal inflammationLynn Bonetti1,2, Veronika Horkova1,2, Luana Guerra1,2, Henry Kurniawan1,2, Davide G Franchina1,2, Leticia Soriano-Baguet1,2, Melanie Grusdat1,2, Sabine Spath3,4, Eric Koncina5, Anouk Ewen1,2, Joseph Longworth1,2, Carole Binsfeld1, Charlene Verschueren1, Jean-Jacques Gérardy6,7, Takumi Kobayashi1,2, Catherine Dostert1,2, Sophie Farinelle1, Ying Chen8, Isaac S Harris9, Vasilis Vasiliou8, Elisabeth Letellier10, Burkhard Becher3, Michel Mittelbronn2,6,7,10,11,12, and Dirk Brenner1,2,13
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78 |
Resting CD4+ T cells exposed to oleic acid upregulate genes involved in immunometabolism resulting in increased IL-9+ frequencies post-activationNathalie A Reilly1, Koen F Dekkers1, Friederike Sonnet2, Lucy Sinke1, Joanneke C Kwekkeboom3, Ellen van der Voort3, Andreea Ioan-Facsinay3, Wouter J Jukema4, and Bastiaan T Heijmans1
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79 |
Lactate: a new alternative pathway of mesenchymal stem/stromal cells immunosuppressive propertiesCarolina Pradenas2,1, Noymar Luque2,1, Karina Oyarce-Merino4, Rafael Contreras1, Felipe Galvez1, Ana Maria Vega-Letter2,1, Farida Djouad5, Roberto Elizondo-Vega3, and Patricia Luz-Crawford2,1
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80 |
Impaired glucocorticoid receptor signaling disrupts glucose immunometabolism in malariaFran Prenen1, Leen Vandermosten1, Pauline Dagneau de Richecour1, Sofie Knoops1, Emilie Pollenus1, Hendrik Possemiers1, Giorgio Caratti2, Christopher Cawthorne3, Sabine Vettorazzi2, Christophe Deroose3, Uwe Himmelreich3, Jan Tuckerman2, and Philippe Van den Steen1
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81 |
K63-linked ubiquitination regulates innate-dependent antiviral immunityAnouk Ewen1,2, Catherine Dostert1,2, Veronika Horkova1,2, Joseph Longworth1,2, Takumi Kobayashi1,2, Janika Härm1,2, Melanie Grusdat1,2, Leticia Soriano-Baguet1,2, and Dirk Brenner1,2,3
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82 |
Glutaminase-1 activity supports a hypermetabolic phenotype and a Th1/Th17 cytokine profile in CD4+ T cells from people with prediabetes and type 2 diabetesGabriella H Kalantar1, Sara SantaCruz-Calvo2, Leena P Bharath3, Shubh Saraswat4, Xiaohua Douglas Zhang4, Ann Caroline Hawk1, Rui Liu5, Philip A Kern6, and Barbara S Nikolajczyk1,2,5,7
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83 |
Computational modelling reveals metabolic activities in different macrophage populationsRoko Sango1,3,, Andrea Vogel1, Thomas Weichhart1, and Thomas Rattei3,
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84 |
Targeting ACC1 in T cells ameliorates psoriatic skin inflammation.Yu-San Kao
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85 |
The effect of metformin and 2-deoxy-D-glucose on determinants of anti-tumor T cell response as a function of glucose availability in vitroJernej Repas1, Lea Peternel1, Harald Sourij2, and Mojca Pavlin1,3
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86 |
A comparative multi-omics analysis during nutrient stress reveals conserved and nutrient-specific regulatory networks in CD8+ T cellsMichael Scaglione1,2, Kelly Rome1, Krittin Trihemasava1,2, Chao Di1, Montana Knight1, Crystal Conn3, and Will Bailis1,2
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87 |
Apoptotic cell engulfment and digestion in macrophages triggers synthesis of bioactive lipids to promote regenerationConnor Lantz1, Amanda Becker2, Mallory Filipp1, and Edward Thorp1
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88 |
Unique Adipose Invariant Natural Killer T Cell Subpopulations Control Adipocyte Turnover by Orchestrating Cellular CrosstalkSang Mun Han1, Eun Seo Park2, Jeu Park1, Jong Kyoung Kim3, and Jae Bum Kim1
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89 |
The Role of the hemochromatosis Protein HFE in Metabolism Paul Knoop1, Banu Akdogan 2, Hans Zischka2,3, and Maja Vujić Spasić1
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90 |
TYPE 2 DIABETES IS ASSOCIATED WITH INCREASED CYTOKINE PRODUCTION BY CYTOTOXIC BLOOD LYMPHOCYTESDora Gašparini1,2, Inga Kavazović1, Željka Mijolović2, Igor Klarić3, Adriana Prunk Dermić4, Viktor Peršić3, Tamara Turk Wensveen2,5, and Felix M Wensveen1
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91 |
Deciphering liver macrophage heterogeneity and their role in metabolism regulationCamille BLERIOT1, Florent GINHOUX2, and Nicolas VENTECLEF1
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92 |
Ménage à trois: Neuro-endocrino-immune regulation of metabolic homeostasis Marko Šestan1, Bruno Raposo1, Miguel Rendas1, David Brea1, Roksana Pirzgalska1, Roel G. J. Klein Wolterink1, Inês Godinho1, Hélder Ribeiro1, Tânia Carvalho1, Stephan Wueest2,3, Daniel Konrad2,3,4, and Henrique Veiga-Fernandes1
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93 |
Innate lymphoid cells type 2 and CD8+ T cells are perturbed in overweight and obese individuals with asthmaSofia Björkander1, Paul Maier2, Maura Kere1, Simon Kebede Merid 2, Lorenz Wirth2, Whitney Weigel 2, Sabrina de Souza Ferreira2, Jenny Mjösberg2,3, Erik Melén2,3, and Christopher Andrew Tibbitt2,3
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94 |
NKG2D-mediated immunesensing of metabolically stressed hepatocytes by innate-like T cells is essential for initiation of NASH and fibrosis
Sonja Marinović9, Maja Lenartić9, Karlo Mladenić9, Marko Šestan9, Inga Kavazović9, Ante Benić9, Mia Krapić9, Lukas Rindlisbacher2, Colin Sparano2, Gioana Litscher2, Tamara Turk Wensveen4, Dora Fučkar Čupić5, Lidija Bilić-Zulle6, Aleksander Steinle7, Ari Waisman8, Adrian Hayday9, Sonia Tugues2, Burkhard Becher2, Ivana Mikolaševuć3, Felix M Wensveen9, and Bojan Polić9
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95 |
Endogenous glucocorticoids protect against immunometabolic deregulation in malariaLeen Vandermosten1, Fran Prenen1, Balotin Fogang2, Karolina Zielinska1, Pauline Dagneau de Tichecour1, Sofie Knoops1, Emilie Pollenus1, Hendrik Possemier1, Giorgio Caratti3, Christopher Cawthorne4, Sabine Vetorazzi3, Christophe M Deroose4, Uwe Himmelreich4, Karolien De Bosscher6, Bart Ghesquière5, Jan Tuckerman3, Lawrence Ayong2, and Philippe E Van den Steen1
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96 |
Itaconate suppresses alternative activation of macrophages and alters responses in the lung tumor microenvironmentMarah C Runtsch2, Oliver Kindler2, Alexander Hooftman1, Ridhima Wadhwa5, Yanling Zhang4, Anne F McGettrick1, Philip M Hansbro5, Chu Wang4, Stefano Angiari3, Julia Kargl2, and Luke A.J. O'Neill1
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97 |
Impact of mechanical Stimulation on Macrophage Polarization and EfferocytosisDenis Nalbantoglu1, Sabine Vettorazzi1, Jan Tuckermann1, and Kay Gottschalk2
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98 |
Investigating the metabolic regulation of conventional dendritic cells and how it is altered between tissues.Robert Hearnden1,2, Valle Morales1, M Paula Longhi2, and Katiuscia Bianchi1
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99 |
Reductive carboxylation epigenetically instructs effector T cell differentiationAlison L Jaccard1, Tania Wyss3, Noelia Maldonado-Pérez4, Jan A Rath5, Alessio Bevilacqua1, Jhan-Jie Peng1, Anouk Lepez7, Christine Von Gunten5, Fabien Franco1, Kung-Chi Kao1, Nicolas Camviel5, Francisco Martín4, Denis Migliorini7, Caroline Arber5, Pedro Romero1, Ping-Chih Ho1, and Mathias Wenes7
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100 |
Functional characterization of MHCII-mediated antigen presentation by intestinal epithelial cells in obese mice Christian Vossen1, Claudia Maria Wunderlich1, Jens Claus Brüning2,, and Thomas Frank Wunderlich1,
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101 |
Obesity increases disease severity and alters the host immune response to influenza infectionVictoria Meliopoulos1, Brandi Livingston1, Virginia Hargest1, Rebekah Honce2, Lauren Lazure1, Bridgett Sharp1, Pamela Freiden1, and Stacey Schultz-Cherry1
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102 |
Opa1 supports biomass accumulation in rapidly dividing CD8 T cellsBenjamin A Willett, Jared Klarquist, and Ross Kedl
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103 |
Investigating the effects of weight loss on NK cell metabolism and functionKatie L O'Brien1, John Scanlon1, Hannah Prendeville1, and Lydia Lynch1,2
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104 |
Immunometabolic alterations and immunophenotype of mononuclear cells in children with multi-system inflammatory syndrome (MIS-C) Mojca Pavlin1,2, Andreja Nataša Kopitar3, Jernej Repas1, Janežič Larisa3, Bizjak Masa4, Tina Vesel Tanjšek4, Nina Emeršič 4, Mojca Zajc Avramovič4, Alojz Ihan3, and Tadej Avčin4,5
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105 |
Intercellular transfer within tumor microenvironment Kaito Hioki, Leonid Pobezinsky, and Elena Pobezinskaya
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106 |
The lysosomal calcium channel TRPML1 regulates mitochondrial fitness and autophagy in Natural Killer cellsDennis Clement2, Edina Krisztina Szabo2, Silje Z Krokeide1, Merete T Wiiger2, Marianna Vincenti2, Daniel A.O Palacios2, Andreas Brech3, Harald Stenmark3, Rakesh Kumar Majhi1, and Karl-Johan Malmberg1
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107 |
FoxP3 expression in regulatory T cells is regulated by Acetyl-CoA availability
Philipp Stüve2, Janet G Godoy1, Tim D Sparwasser2, and Luciana Berod1
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108 |
SVEP1-based peptide as a therapeutic agent against adipose tissue dysfunctionNadav Kislev and Dafna Benayahu
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109 |
Kv1.3 potassium channel of myeloid cells controls tumor growth in vivoTatiana Varanita1, Beatrice Angi1, Anna Rodella2,3, Daniele Bonesso1, Anna Tosi4, Mattia Albiero2,3, Enrica Calura1, Matteo Parri6, Paola Chiarugi6, Gian Paolo Fadini2,3, Ferenc Erdelyi7, Antonio Rosato4,5, and Ildiko Szabo1
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110 |
Methylglyoxal has no direct effect on immune cell recruitment or activation but is involved in trained immunityKristiaan Wouters1, Xiaodi Zhang1, Jean L Scheijen1, Philippe Vangrieken1, Jaycey Kelly1, Thom E Kusters1, Julia IP van Heck2, Rinke Stienstra2,3, and Casper G Schalkwijk1
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111 |
Characterization of regulatory T cell - specific Kv1.3 knock-out mouse modelBeatrice Angi1, Tatiana Varanita1, Ferenc Erdelyi2, Zsuzsanna Keresztesi2, Claudia Russo3, Giusy De Rosa5, Claudio Procaccini3,, Giuseppe Matarese5,, and Ildiko Szabo1
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112 |
The role of macrophages in adipocyte degradation - the role of lysosomal exocytosisRaphaela Wehr, Nora Raulien, and Martin Gericke
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113 |
Does JAZF1 maintain metabolic homeostasis in human TregKate L Shepherdson1, Christopher M Hope1, Ying Y Wong1, Hannah R Morgan1, Tim Sadlon1,2, Cheryl Y Brown1, and Simon C Barry1,2
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114 |
A short chain fatty acid derivative with high bioavailability reduced plaque coverage and suppresses inflammation in a murine model of atherosclerosis Taryn N Beckman1,2, Lisa R Volpatti1, Shijie Cao1, Gustavo Borjas 1, and Jeffery A Hubbell1
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115 |
Activation of S1P/SK2 pathway in classical monocytes enhances anti-PD-1 immunotherapy.Silvia Guglietta2, Mark D Robinson4, Wenjian Gan3, Gyda Beeson2, and Carsten Krieg1
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116 |
The metabolic effects of Semaphorin3A on human T cells during homeostasis and immune-mediated diseasesRaeda M Mubariki
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117 |
Effect of cold water immersion on bone mineral metabolism and inflammatory status in aging ratsIrena Baranowska-Bosiacka, Mateusz Bosiacki, Anna Lubkowska, and Dariusz Chlubek
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118 |
Energy metabolism, mitochondrial biogenesis and CXCL1/CXCR2 expression in muscles of rats subjected to cold water immersionMateusz Bosiacki1, Anna Lubkowska2, Dariusz Chlubek1, and Irena Baranowska-Bosiacka1
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119 |
Neuroinflamation Induced by Pre- and Neonatal Exposure to Lead (Pb)Patrycja Kupnicka1, Mikołaj Chlubek1, Magdalena Gąssowska-Dobrowolska2, Jan Korbecki1, Jakub Kwiatkowski1, and Irena Baranowska-Bosiacka1
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120 |
Changes in the activity of metalloproteinases and their inhibitors in the brain after exposure to fluorideIzabela Gutowska1, Irena Baranowska-Bosiacka2, Agnieszka Łukomska4, Wojciech Żwierełło1, Marta Skórka-Majewicz1, and Anna Pilutin3
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121 |
Cytomegalovirus (CMV) alters mitochondrial biogenesis by directly affecting the function of complex I and complex II in the electron transport chain (ETC), which results in macrophage polarizationMohammad Pirouzfar1, Tong Liu2, Leah Cui2, Hatem Abouguendia 1, and Cecilia Söderberg-Naucler1,2
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122 |
Cytomegalovirus binds to endothelin B receptor and results in metabolic rewiring that is essential for virus replicationHatem Abouguendia1, Koon-Chu Yaiw2, Jennifer Gorwood2, and Cecilia Söderberg-Nauclér1,2
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123 |
HCMV promotes BC progression through PTPMT1-mediated metabolic rewiring and Th17 differentiation and enhanced IL-17R expressionShaghayegh Hasanpour
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Viperin- A cytomegalovirus (CMV) driven immunometabolic switch?Iqra Anam Khawaja
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Cytomegalovirus binds to endothelin B receptor and results in metabolic rewiring that is essential for virus replicationHatem Abouguendia, Koon-Chu Yaiw, Jennifer Gorwood, and Cecilia Söderberg-Nauclér,
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126 |
HCMV promotes BC progression through PTPMT1-mediated metabolic rewiring and Th17 differentiation and enhanced IL-17R expressionShaghayegh Hasanpour, Hatem Abouguendia, and Cecilia Söderberg Näucler
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127 |
Obesity and aging interactions modify the breast microbiome influencing tumorigenesis and immune cell populations within the microenvironment Kenysha YJ Clear1, Neil M Iyengar2, Akiko Chiba3, Marissa Howard-McNatt1, Alexandra Thomas1, David R. Soto-Pantoja1, and Katherine L Cook1
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128 |
Immune bioenergetic, metabolic, and genetic signatures as biomarkers of immune checkpoint therapy response.Pierre L Triozzi, Qianqian Song, Lance D. Miller, Wei Zhang, Katherine L. Cook, and David R. Soto-Pantoja
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129 |
HCMV promotes BC progression through PTPMT1 mediated metabolic rewiring and Th17
differentiation and enhanced IL-17R expressionShaghayegh Hasanpour, Hatem Omar Aboughuendia, and Cecilia SOderberg Naucler
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