8th International Conference on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging and Therapeutic Targets

Posters

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Ectopic expression of cancer/testis antigen NANOS3 promotes cancer invasiveness
Erkut Ilaslan, Kamila Kusz-Zamelczyk, and Jadwiga Jaruzelska
A CRISPR/Cas9 tool for genome-wide interrogation of essential MYC binding sites
Marta Kazimierska1, Marta Podralska3, Magdalena Żurawek1, Tomasz Woźniak4, Marta Kasprzyk1, Weronika Sura1, Iwona Ziółkowska-Suchanek1, Joost Kluiver2, Anke van den Berg2, Natalia Rozwadowska1, and Agnieszka Dzikiewicz-Krawczyk1
Exploring the role of epithelial cancer cell-derived collagen in PDAC tumorigenicity
Donatella Delle Cave, Annalisa Di Domenico, Ilaria Di Biase, Marianna Ciotola, and Enza Lonardo
Development and Preclinical Characterization of Bispecific Monoclonal Antibody (BiMAb) for Colorectal Cancer Immunotherapy
Norah Alrishedan
Juvenil, the natural immune booster affects the proliferation of tumor cells
Vanda Bostikova and Klara Kubelkova
ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer
Tom Keulers1, Alexander Koch2, Marike Van Gisbergen3, Lydie Barbeau1, Marijke Zonneveld1, Kim Savelkouls1, Roel-Germ Wanders1, Jan Bussink5, Veerle Melotte2, Monique de Jong4, and Kasper Rouschop1
A novel antibody targeting the tumor microenvironment antigen Fibroblast Activation Protein Alpha highlights a potential broad cancer theranostic approach.
Joseph Gallant1,5, Hallie Hintz2, Zack Rosenkrans3, Austin Robertson1,5, Natalie Luo1, Abigail Jackson1, Jayden West1, Reinier Hernandez3,4, and Aaron LeBeau1,4
Liposomal nanocarriers for tumor imaging
Mohamad Ahrari
Effect of melanoma cell exosomes on normal and tumor-associated fibroblasts
Lucie Pfeiferová1,4, Karolína Strnadová2,3, Petr Přikryl5, Barbora Dvořánková2,3, Erik Vlčák6, Jana Frýdlová5, Martin Vokurka5, Jiří Novotný1,4, Jana Šáchová1, Miluše Hradilová1, Jan Brábek3, Jana Šmigová3, Daniel Rösel3, Karel Smetana, Jr.2,3, Michal Kolář1, and Lukáš Lacina2,3
Shrinkage of CD14+ monocyte/macrophage lineage cells in tumor microenvironment contributes to the expansion of CD90+ cells
Alexandros Tzingounis1, Agapi Kataki2, Loukas Stoupis1, Ioanna Angelioudaki1, Alexandros Mitrousias1, Loukas Rentifis2, Anastasia Derventzi2, Georgios Zografos2, and Manousos Konstadoulakis1
Inflammatory role of CD44v6+ cells in the interaction of pancreatic cancer with its microenvironment
Alexandros Tzingounis1, Agapi Kataki2, Ioanna Angelioudaki1, Efthymios Koniaris3, Loukas Rentifis2, Georgios Giokas1, Georgios Zografos2, and Manousos Konstadoulakis1
Tristetraprolin promotes mammary progenitor cell survival by inhibiting the TNFα-p38 signaling pathway
Micaela Stedile1, Ángela Lara Montero1, Martín García Solá1, Inés Beckerman1, Emilia Bogni2, Marina Ayre1, Zaira Naguila3, Omar Coso1, and Edith Kordon2
A muscadine grape extract inhibits trastuzumab-resistant HER2 positive breast cancer and prevents trastuzumab-induced cardiotoxicity
Jessica Mackert, Patricia Gallagher, and E Tallant
A muscadine Grape Extract Enriched in Dietary Polyphenols Reduces Breast Tumor-Associated Fibrosis in an MMTV-Transgenic Mouse Model
Ana Clara Melo, E. Ann Tallant, and Patricia Gallagher
Spatially Resolved mRNA Profiling of Vestibular Swannoma
Jana Šáchová1, Zdeněk Fík3, Miluše Hradilová1, Michaela Tesařová3, Peterková Lenka3, Monika Šťastná2, Michal Kolář1, and Jan Plzák3
Effects of MCL-1 inhibitor in trametinib-resistant melanoma cells on drug holiday
Paulina Tecza, Katarzyna Kluszczynska, Malgorzata Sztiller-Sikorska, Mariusz Hartman, and Malgorzata Czyz
Anti-CD47 immunotherapy modulates T cell bioenergetics to potentiate anti-tumor responses
Elizabeth Stirling, Adam Wilson, Mitra Kooshki, Liliya Yamaleyeva, Pierre Triozzi, and David Soto-Pantoja
Enhancing tumor perfusion to improve drug delivery and tumor immune-microenvironment
Jeong Uk Choi
Investigation of effects of acetylsalicylic acid on pancreatic stellate cells-mediated pancreatic cancer aggressiveness.
Sıla Sığırlı3, Didem Karakaş1, and Engin Ulukaya2
Innate Immune Recognition, Autonomous Defence Mechanisms, and Tumorigenesis
Klara Kubelkova and Ales Macela
Telomere to mitochondria signaling prevents cancer initiation
Joe Nassour, Lucia Aguiar, Adriana Correia, Tobias Schmidt, Laura Mainz, Sara Przetocka, Gerald Shadel, and Jan Karlseder
FLASH radiation research at Oxford Institute for Radiation Oncology
Kristoffer Petersson
De novo steroidogenesis in tumor cells drives bone metastasis formation and osteoclastogenesis
Peter Benko1, Huh Joon1, Toru Hiraga2, Bidesh Mahata3, and David Gyori1
Tamoxifen-induced activation of Type I IFN signaling and its putative role in hormone and immunotherapy resistance of ER-positive breast cancer
Marvin Aberin1,2, Chen-Yang Shen1, Yao-Ming Chang1, and Shu-Ping Wang1,2
Histone H3K4 methyltransferase KMT2D/MLL4 controls leukemia cell survival through regulation of mitochondria and cellular redox homeostasis
Ta-Yu Liu1,2, Hsiao-Chin Hong2, Yu-Wen Chen2, Lan-Hsin Wang3, Yao-Ming Chang2, Chun-Wei Chen4, Robert Roeder5, and Shu-Ping Wang1,2
Effects of Muscadine Grape Extract on prostate cancer bone metastasis
Bethany Kerr
Relationship between structural-mechanical properties of extracellular matrix and its ability to repopulation by cancer cells studied on decellularized organs
Anton Pospelov1, Olga Kutova1, Yuri Efremov4, Albina Nekrasova4, Daria Trushina3, Sofia Gefter1, Elena Cherkasova1, Lidia Timofeeva2, Andrey Zvyagin4, Peter Timashev4, and Irina Balalaeva1