15th International Conference on Complement Therapeutics

Authors List

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Author Abstracts
Lorentzen Josefine structural insight on the function of properdin in the alternative pathway
Pedersen Dennis structural insight on the function of properdin in the alternative pathway
Adegbuyi George Complement Factor B activation test specificity in the rapid test format: generation and characterization of new Ba neo-epitope specific monoclonal antibodies
Adler Anna An alternative binding and activation mechanism of native C3 induced by contact with biosurfaces without involvement of the thioester
Afzali Ben C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection
Aiuti Alessandro The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Amal Haitham Aberrant protein S-nitrosylation of C3 activates phagocytosis of neuronal synapses by microglia in Alzheimer's disease
Andersen Gregers structural insight on the function of properdin in the alternative pathway
Anstadt Robert Age-related Macular Degeneration: a Tale of Two RPE-centric Diseases, of Which Only One is Complement-driven
Arguelles Gabriel Distinct cell-bound complement activation products associate with disease activity and immune transcriptional programs in systemic lupus erythematosus
Asselta Rosanna The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Atkinson Carl Natural antibody targeted complement inhibitor ameliorates the development of chronic heart and lung transplant rejection
Distinct cell-bound complement activation products associate with disease activity and immune transcriptional programs in systemic lupus erythematosus
Ayoub Ikram Cerebrospinal fluid proteomics in recent-onset Narcolepsy type 1 reveals activation of the complement system
Banda Nirmal RNA Profiling and protein expression studies in the synovium of both rheumatoid arthritis and post-traumatic injury identify causal pathogenic mechanisms for complement activation in both diseases
Barr Johnny Immunopathology of Terminal Complement Activation and Complement C5 Blockade Creating a Pro-survival and Organ-protective Phenotype in Trauma
Barrie Jennifer Complement inhibition prevents paranodal loop injury in an anti-GM1 antibody-mediated paranodal demyelinating mouse model.
Barta Bálint The COVID-19 mRNA vaccine Comirnaty induces anaphylactic shock in an anti-PEG hyperimmune pig model: Role of complement activation in cardiovascular, hematological and inflammatory mediator changes
Barzaghi Federica The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Bates Lucy Evaluation of minimal factor H therapy administered to kidneys during ex vivo normothermic perfusion as a treatment to improve ischaemia reperfusion injury
Bathini Praveen A MaGical cASe: a story on the cell-specific effects of C3-mediated neurodegeneration
Batista Andre A MaGical cASe: a story on the cell-specific effects of C3-mediated neurodegeneration
Generation and characterization of C3 inducible conditional KO Alzheimer’s-like mice
Bechtler Clément Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Bevan Ryan The role of terminal pathway in driving pathology in dementia.
Blagojevic Aleksandra Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Blom Anna Bacterial evasion strategy as basis for novel antimicrobial treatment.
Boeke Jef Xenotransplantation: Using Genome Editing to Overcome Pig-to-Human Incompatibilities.
Bondesan Simone The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Borucki Davis The immune cell landscape of the injured brain and its relation to the complement system in traumatic brain injury
Bottazzi Barbara Involvement of PTX3 and MBL in the clearance of SARS-CoV-2 infected lung airway epithelial cells
The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Boudhabhay idris Complement activation as a biomarker and pathogenic factor in rhabdomyolysis-induced acute kidney injury
In situ Complementomics in kidney diseases and cancer
Bourdin Antonin In situ Complementomics in kidney diseases and cancer
Bracke Laura Complement inhibition prevents paranodal loop injury in an anti-GM1 antibody-mediated paranodal demyelinating mouse model.
Brekke Ole The Escherichia coli-induced platelet aggregation in human whole blood is inhibited by compstatin and is C3b dependent
Busch Andreas Glycan structure optimization of moss produced human complement factor H markedly improves pharmacokinetic and pharmacodynamics properties in vivo.
Butler Samuel A Novel Functional Properdin Assay – Studying the Positive AP Regulator and Complement Amplification Loop
Caillard Sophie Ex vivo complement activation on endothelial cells: set up of a new functional tool to explore complement dysregulation
Campbell Clare Complement inhibition prevents paranodal loop injury in an anti-GM1 antibody-mediated paranodal demyelinating mouse model.
Cancio Leopoldo Immunopathology of Terminal Complement Activation and Complement C5 Blockade Creating a Pro-survival and Organ-protective Phenotype in Trauma
Carrera Paola The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Carroll Michael Generation and characterization of C3 inducible conditional KO Alzheimer’s-like mice
Casari Giorgio The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Cervenak László C1-INH complexes as markers for classical and lectin pathway activation
Chauvet Sophie Correlation of systemic and in situ biomarkers of complement activation with histopathological features and prognosis in C3 glomerulopathy.
In situ Complementomics in kidney diseases and cancer
Impact of C3 and soluble C5b-9 levels on renal outcomes in C3 glomerulopathy : results from a national-wide retrospective cohort
Chen Xi Compstatins abolish pathogenic fibroblast function associated with inflammatory tissue priming
Christiansen Dorte The Escherichia coli-induced platelet aggregation in human whole blood is inhibited by compstatin and is C3b dependent
Chu Shu-Hui New Shot on Goal: Targeting Inflammation and Synapse Loss to Suppress Alzheimer’s Disease
Chung Hyewon Differential proteins including complement factor H in the aqueous humor from patients with dry age-related macular degeneration (AMD)
Connelly Chloe Evaluation of minimal factor H therapy administered to kidneys during ex vivo normothermic perfusion as a treatment to improve ischaemia reperfusion injury
Connolly E progressive neurological injury, early neurological deterioration and microvascular dysfunction following endovascular thrombectomy for larger vessel stroke: a target for anti-complement therapeutics
Cooper Madison Evaluation of minimal factor H therapy administered to kidneys during ex vivo normothermic perfusion as a treatment to improve ischaemia reperfusion injury
Cunningham Madelaine Complement inhibition prevents paranodal loop injury in an anti-GM1 antibody-mediated paranodal demyelinating mouse model.
Curtin Karen Age-related Macular Degeneration: a Tale of Two RPE-centric Diseases, of Which Only One is Complement-driven
Dabrowska-Schlepp Paulina Glycan structure optimization of moss produced human complement factor H markedly improves pharmacokinetic and pharmacodynamics properties in vivo.
Delaere Jolien Complement inhibition prevents paranodal loop injury in an anti-GM1 antibody-mediated paranodal demyelinating mouse model.
Delahaye Tim Complement inhibition prevents paranodal loop injury in an anti-GM1 antibody-mediated paranodal demyelinating mouse model.
Desai Jigar C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection
Domingo Enric Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy
Donado Carlos Granzyme K activates a new complement pathway
Duan Huiquan Continued investigations of modified DNA aptamers as inhibitors of complement proteins and their complexes
Dührkop Claudia An alternative binding and activation mechanism of native C3 induced by contact with biosurfaces without involvement of the thioester
Duong Jean-Paul Correlation of systemic and in situ biomarkers of complement activation with histopathological features and prognosis in C3 glomerulopathy.
Duval Anna Correlation of systemic and in situ biomarkers of complement activation with histopathological features and prognosis in C3 glomerulopathy.
Ex vivo complement activation on endothelial cells: set up of a new functional tool to explore complement dysregulation
Ebert Roland An alternative binding and activation mechanism of native C3 induced by contact with biosurfaces without involvement of the thioester
Edsall Peter Immunopathology of Terminal Complement Activation and Complement C5 Blockade Creating a Pro-survival and Organ-protective Phenotype in Trauma
Ekdahl Kristina An alternative binding and activation mechanism of native C3 induced by contact with biosurfaces without involvement of the thioester
Elvington Michelle Complement Factor B activation test specificity in the rapid test format: generation and characterization of new Ba neo-epitope specific monoclonal antibodies
Emblem Åse The Escherichia coli-induced platelet aggregation in human whole blood is inhibited by compstatin and is C3b dependent
Fageräng Beatrice Aspergillus fumigatus induces tumor necrosis factor release in a complement C3-dependent manner in lepirudin anticoagulated human whole blood
Felsch Jannes Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Fleckenstein Monika Age-related Macular Degeneration: a Tale of Two RPE-centric Diseases, of Which Only One is Complement-driven
Fosso Bruno Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy
Frazer-Abel Ashley Stratification of patients with complement mediated diseases for complement targeted therapies: the perspective from the diagnostic complement laboratory
Frémeaux-Bacchi Véronique Correlation of systemic and in situ biomarkers of complement activation with histopathological features and prognosis in C3 glomerulopathy.
Comprehensive genetic evaluation for the diagnosis of complement alternative pathway-mediated kidney diseases
Ex vivo complement activation on endothelial cells: set up of a new functional tool to explore complement dysregulation
Frieri Camilla A new treatment paradigm for Paroxysmal Nocturnal Hemoglobinuria: the era of proximal complement inhibitors
Friscic Jasna Compstatins abolish pathogenic fibroblast function associated with inflammatory tissue priming
Fromell Karin An alternative binding and activation mechanism of native C3 induced by contact with biosurfaces without involvement of the thioester
Fung Jenny Identification of genes involved in the protective response of C3aR in amyotrophic lateral sclerosis pathology
A detrimental role for complement C5aR1 activation in Huntington’s disease
Gadeberg Trine structural insight on the function of properdin in the alternative pathway
Garlanda Cecilia The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Involvement of PTX3 and MBL in the clearance of SARS-CoV-2 infected lung airway epithelial cells
Garred Peter Aspergillus fumigatus induces tumor necrosis factor release in a complement C3-dependent manner in lepirudin anticoagulated human whole blood
Geisbrecht Brian Continued investigations of modified DNA aptamers as inhibitors of complement proteins and their complexes
Gerogianni Alexandra The Escherichia coli-induced platelet aggregation in human whole blood is inhibited by compstatin and is C3b dependent
Gibson Beth Evaluation of minimal factor H therapy administered to kidneys during ex vivo normothermic perfusion as a treatment to improve ischaemia reperfusion injury
An Oral C5aR receptor antagonist blocks disease in the C3 gain-of-function mouse model of aHUS.
Golomingi Murielle Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Gomez-Arboledas Angela New Shot on Goal: Targeting Inflammation and Synapse Loss to Suppress Alzheimer’s Disease
Götz Maximilian Aspergillus fumigatus induces tumor necrosis factor release in a complement C3-dependent manner in lepirudin anticoagulated human whole blood
Griesemer Adam Xenotransplantation: Using Genome Editing to Overcome Pig-to-Human Incompatibilities.
Grunenwald Anne Complement activation as a biomarker and pathogenic factor in rhabdomyolysis-induced acute kidney injury
Guglietta Silvia Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy
The immune cell landscape of the injured brain and its relation to the complement system in traumatic brain injury
Guido Poli Involvement of PTX3 and MBL in the clearance of SARS-CoV-2 infected lung airway epithelial cells
Häffner Karsten Glycan structure optimization of moss produced human complement factor H markedly improves pharmacokinetic and pharmacodynamics properties in vivo.
Hageman Gregory Age-related Macular Degeneration: a Tale of Two RPE-centric Diseases, of Which Only One is Complement-driven
Hajishengallis George Probing C3 modulation in the intracellular space: Cellular internalization of compstatin-based C3 inhibitors and its functional implications
Mechanistic and therapeutic aspects in complement-driven periodontal disease
Hamad Osama An alternative binding and activation mechanism of native C3 induced by contact with biosurfaces without involvement of the thioester
Hasturk Hatice Mechanistic and therapeutic aspects in complement-driven periodontal disease
Hevey Rachel Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Hill-Pryor Crystal Immunopathology of Terminal Complement Activation and Complement C5 Blockade Creating a Pro-survival and Organ-protective Phenotype in Trauma
Hoffmann Markus Compstatins abolish pathogenic fibroblast function associated with inflammatory tissue priming
Holers V Michael RNA Profiling and protein expression studies in the synovium of both rheumatoid arthritis and post-traumatic injury identify causal pathogenic mechanisms for complement activation in both diseases
Hourcade Dennis Distinct cell-bound complement activation products associate with disease activity and immune transcriptional programs in systemic lupus erythematosus
Hoyler Thomas An Oral C5aR receptor antagonist blocks disease in the C3 gain-of-function mouse model of aHUS.
Hurler Lisa C1-INH complexes as markers for classical and lectin pathway activation
Izzo Francesca The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Jonsson Helena Granzyme K activates a new complement pathway
Kajdácsi Erika C1-INH complexes as markers for classical and lectin pathway activation
Karlsen Bård The Escherichia coli-induced platelet aggregation in human whole blood is inhibited by compstatin and is C3b dependent
Kavian-Tessler Niloufar Involvement of PTX3 and MBL in the clearance of SARS-CoV-2 infected lung airway epithelial cells
Keating Brendan Xenotransplantation: Using Genome Editing to Overcome Pig-to-Human Incompatibilities.
Kemper Claudia C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection
Khan Khyrul Generation and characterization of C3 inducible conditional KO Alzheimer’s-like mice
Kim Alfred Distinct cell-bound complement activation products associate with disease activity and immune transcriptional programs in systemic lupus erythematosus
Xenotransplantation: Using Genome Editing to Overcome Pig-to-Human Incompatibilities.
King Ben Cytosolic C3 in cellular homeostasis and defence
Kirschfink Michael Stratification of patients with complement mediated diseases for complement targeted therapies: the perspective from the diagnostic complement laboratory
Köhl Jörg C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection
Konwar Swagata Glycan structure optimization of moss produced human complement factor H markedly improves pharmacokinetic and pharmacodynamics properties in vivo.
Kozma Viktoria A Novel Functional Properdin Assay – Studying the Positive AP Regulator and Complement Amplification Loop
Krieg Carsten Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy
The immune cell landscape of the injured brain and its relation to the complement system in traumatic brain injury
Kulkarni Hrishikesh S Modulation of lung injury by tissue-specific C3 expression
Lambris John Mechanistic and therapeutic aspects in complement-driven periodontal disease
A new treatment paradigm for Paroxysmal Nocturnal Hemoglobinuria: the era of proximal complement inhibitors
Compstatins abolish pathogenic fibroblast function associated with inflammatory tissue priming
Probing C3 modulation in the intracellular space: Cellular internalization of compstatin-based C3 inhibitors and its functional implications
Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Lambris & collaborators John The dawn of clinical C3 inhibition: the story, its milestones and what lies ahead
Lamers Christina Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Landsem Anne The Escherichia coli-induced platelet aggregation in human whole blood is inhibited by compstatin and is C3b dependent
Lau Corinna The Escherichia coli-induced platelet aggregation in human whole blood is inhibited by compstatin and is C3b dependent
Le Tuan Immunopathology of Terminal Complement Activation and Complement C5 Blockade Creating a Pro-survival and Organ-protective Phenotype in Trauma
Lee Rebecca Probing C3 modulation in the intracellular space: Cellular internalization of compstatin-based C3 inhibitors and its functional implications
Identification of genes involved in the protective response of C3aR in amyotrophic lateral sclerosis pathology
A detrimental role for complement C5aR1 activation in Huntington’s disease
Lemere Cynthia Generation and characterization of C3 inducible conditional KO Alzheimer’s-like mice
A MaGical cASe: a story on the cell-specific effects of C3-mediated neurodegeneration
Lewis Sarah Aberrant protein S-nitrosylation of C3 activates phagocytosis of neuronal synapses by microglia in Alzheimer's disease
Li Shaomin A MaGical cASe: a story on the cell-specific effects of C3-mediated neurodegeneration
Immunopathology of Terminal Complement Activation and Complement C5 Blockade Creating a Pro-survival and Organ-protective Phenotype in Trauma
Natural antibody targeted complement inhibitor ameliorates the development of chronic heart and lung transplant rejection
Liang Heidi New Shot on Goal: Targeting Inflammation and Synapse Loss to Suppress Alzheimer’s Disease
Lill Markus Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Lionakis Michail C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection
Lipton Stuart A. Aberrant protein S-nitrosylation of C3 activates phagocytosis of neuronal synapses by microglia in Alzheimer's disease
Liu Jin Age-related Macular Degeneration: a Tale of Two RPE-centric Diseases, of Which Only One is Complement-driven
Immunopathology of Terminal Complement Activation and Complement C5 Blockade Creating a Pro-survival and Organ-protective Phenotype in Trauma
A detrimental role for complement C5aR1 activation in Huntington’s disease
Loupy Alexander Xenotransplantation: Using Genome Editing to Overcome Pig-to-Human Incompatibilities.
Lund Brian Immunopathology of Terminal Complement Activation and Complement C5 Blockade Creating a Pro-survival and Organ-protective Phenotype in Trauma
Mahendran Balaji Evaluation of minimal factor H therapy administered to kidneys during ex vivo normothermic perfusion as a treatment to improve ischaemia reperfusion injury
Majdi Amine In situ Complementomics in kidney diseases and cancer
Mangiola Massimo Xenotransplantation: Using Genome Editing to Overcome Pig-to-Human Incompatibilities.
Månsson Cecilia A Novel Functional Properdin Assay – Studying the Positive AP Regulator and Complement Amplification Loop
Mantovani Alberto The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Marallag Jianina A detrimental role for complement C5aR1 activation in Huntington’s disease
Marano Luana A new treatment paradigm for Paroxysmal Nocturnal Hemoglobinuria: the era of proximal complement inhibitors
Marchbank Kevin An Oral C5aR receptor antagonist blocks disease in the C3 gain-of-function mouse model of aHUS.
Evaluation of minimal factor H therapy administered to kidneys during ex vivo normothermic perfusion as a treatment to improve ischaemia reperfusion injury
Martinic Marianne An Oral C5aR receptor antagonist blocks disease in the C3 gain-of-function mouse model of aHUS.
Marzano Marinella Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy
Mastellos Dimitris A new treatment paradigm for Paroxysmal Nocturnal Hemoglobinuria: the era of proximal complement inhibitors
Probing C3 modulation in the intracellular space: Cellular internalization of compstatin-based C3 inhibitors and its functional implications
Mechanistic and therapeutic aspects in complement-driven periodontal disease
McGonigal Rhona Complement inhibition prevents paranodal loop injury in an anti-GM1 antibody-mediated paranodal demyelinating mouse model.
Mehta Sapna Xenotransplantation: Using Genome Editing to Overcome Pig-to-Human Incompatibilities.
Meuleman Marie-Sophie Correlation of systemic and in situ biomarkers of complement activation with histopathological features and prognosis in C3 glomerulopathy.
In situ Complementomics in kidney diseases and cancer
Ex vivo complement activation on endothelial cells: set up of a new functional tool to explore complement dysregulation
Mills Dan Complement Factor B activation test specificity in the rapid test format: generation and characterization of new Ba neo-epitope specific monoclonal antibodies
Mitchell Lynne Distinct cell-bound complement activation products associate with disease activity and immune transcriptional programs in systemic lupus erythematosus
Moazami Nader Xenotransplantation: Using Genome Editing to Overcome Pig-to-Human Incompatibilities.
Mollnes Tom A review of the double inhibition of complement and TLRs - from the origin on the bench through animal studies and possible clinical applications.
Aspergillus fumigatus induces tumor necrosis factor release in a complement C3-dependent manner in lepirudin anticoagulated human whole blood
The Escherichia coli-induced platelet aggregation in human whole blood is inhibited by compstatin and is C3b dependent
Montgomery Robert Xenotransplantation: Using Genome Editing to Overcome Pig-to-Human Incompatibilities.
Morgan Paul The role of terminal pathway in driving pathology in dementia.
Complement in neuroinflammatory and neurodegenerative diseases.
Mortazavi Ali New Shot on Goal: Targeting Inflammation and Synapse Loss to Suppress Alzheimer’s Disease
Murphy Mark An Oral C5aR receptor antagonist blocks disease in the C3 gain-of-function mouse model of aHUS.
Nakamura Tomohiro Aberrant protein S-nitrosylation of C3 activates phagocytosis of neuronal synapses by microglia in Alzheimer's disease
Nilsson Bo An alternative binding and activation mechanism of native C3 induced by contact with biosurfaces without involvement of the thioester
Aspergillus fumigatus induces tumor necrosis factor release in a complement C3-dependent manner in lepirudin anticoagulated human whole blood
A Novel Functional Properdin Assay – Studying the Positive AP Regulator and Complement Amplification Loop
The Escherichia coli-induced platelet aggregation in human whole blood is inhibited by compstatin and is C3b dependent
Nunn Miles Immunopathology of Terminal Complement Activation and Complement C5 Blockade Creating a Pro-survival and Organ-protective Phenotype in Trauma
O'Luanaigh Niamh Complement Factor B activation test specificity in the rapid test format: generation and characterization of new Ba neo-epitope specific monoclonal antibodies
O'Neill Mollie Complement Factor B activation test specificity in the rapid test format: generation and characterization of new Ba neo-epitope specific monoclonal antibodies
Oh Chang-ki Aberrant protein S-nitrosylation of C3 activates phagocytosis of neuronal synapses by microglia in Alzheimer's disease
Olcina Monica Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy
Understanding the role of C5aR1 in tumours with immunosuppressive microenvironments
Pagani Isabel Involvement of PTX3 and MBL in the clearance of SARS-CoV-2 infected lung airway epithelial cells
The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Panse Jens Glycan structure optimization of moss produced human complement factor H markedly improves pharmacokinetic and pharmacodynamics properties in vivo.
Papavergi Maria-Tzousi A MaGical cASe: a story on the cell-specific effects of C3-mediated neurodegeneration
Pappas Chris Age-related Macular Degeneration: a Tale of Two RPE-centric Diseases, of Which Only One is Complement-driven
Pappworth Isabel An Oral C5aR receptor antagonist blocks disease in the C3 gain-of-function mouse model of aHUS.
Patel Kunal Natural antibody targeted complement inhibitor ameliorates the development of chronic heart and lung transplant rejection
Pekna Marcela The therapeutic potential of C3aR agonists in the post-acute phase after stroke
Pio Ruben The C5a/C5aR1 axis in tumor-associated myeloid cells
Pouw Richard Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Prohászka Zoltán C1-INH complexes as markers for classical and lectin pathway activation
Stratification of patients with complement mediated diseases for complement targeted therapies: the perspective from the diagnostic complement laboratory
Pusateri Anthony Immunopathology of Terminal Complement Activation and Complement C5 Blockade Creating a Pro-survival and Organ-protective Phenotype in Trauma
Qamar Ali A Novel Functional Properdin Assay – Studying the Positive AP Regulator and Complement Amplification Loop
Rabbani Said Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Radovits Tamas The COVID-19 mRNA vaccine Comirnaty induces anaphylactic shock in an anti-PEG hyperimmune pig model: Role of complement activation in cardiovascular, hematological and inflammatory mediator changes
RATAJCZAK MARIUSZ Both liver-derived and intracellular complement modulate hematopoietic stem/progenitor cell metabolism and stress response.
Revel Margot In situ Complementomics in kidney diseases and cancer
Richards Burt Age-related Macular Degeneration: a Tale of Two RPE-centric Diseases, of Which Only One is Complement-driven
Ricklin Daniel Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Risitano Antonio M. A new treatment paradigm for Paroxysmal Nocturnal Hemoglobinuria: the era of proximal complement inhibitors
Roberson Elisha Distinct cell-bound complement activation products associate with disease activity and immune transcriptional programs in systemic lupus erythematosus
Robinson Mark Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy
Roumenina Lubka Intracellular Functions of Complement proteins in health and in Diseases affecting the Kidney
Complement activation as a biomarker and pathogenic factor in rhabdomyolysis-induced acute kidney injury
In situ Complementomics in kidney diseases and cancer
Ex vivo complement activation on endothelial cells: set up of a new functional tool to explore complement dysregulation
Rumano Merita Probing C3 modulation in the intracellular space: Cellular internalization of compstatin-based C3 inhibitors and its functional implications
Rüthemann Peter Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Saido Takaomi Generation and characterization of C3 inducible conditional KO Alzheimer’s-like mice
Saito Takashi Generation and characterization of C3 inducible conditional KO Alzheimer’s-like mice
Sasaguri Hiroki Generation and characterization of C3 inducible conditional KO Alzheimer’s-like mice
Schahrer Emily Aberrant protein S-nitrosylation of C3 activates phagocytosis of neuronal synapses by microglia in Alzheimer's disease
Schartz Nicole New Shot on Goal: Targeting Inflammation and Synapse Loss to Suppress Alzheimer’s Disease
Schmidt Martin Complement Factor B activation test specificity in the rapid test format: generation and characterization of new Ba neo-epitope specific monoclonal antibodies
Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Schmitz-Valckenberg Steffen Age-related Macular Degeneration: a Tale of Two RPE-centric Diseases, of Which Only One is Complement-driven
Schroeder Verena Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Generation and characterization of C3 inducible conditional KO Alzheimer’s-like mice
Schwardt Oliver Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Schwenkert Michael A Novel Functional Properdin Assay – Studying the Positive AP Regulator and Complement Amplification Loop
Seager Nathan Age-related Macular Degeneration: a Tale of Two RPE-centric Diseases, of Which Only One is Complement-driven
Segerstein Therese A Novel Functional Properdin Assay – Studying the Positive AP Regulator and Complement Amplification Loop
Sheerin Neil Evaluation of minimal factor H therapy administered to kidneys during ex vivo normothermic perfusion as a treatment to improve ischaemia reperfusion injury
Shoibonov Batozhab Determining the activity of the alternative and lectin path of the complement system in the fibrinogen coagulation test to predict of the severity of the COVID-19
Sievert Christian Glycan structure optimization of moss produced human complement factor H markedly improves pharmacokinetic and pharmacodynamics properties in vivo.
Simovic Milomir Immunopathology of Terminal Complement Activation and Complement C5 Blockade Creating a Pro-survival and Organ-protective Phenotype in Trauma
Singh Brijendra A MaGical cASe: a story on the cell-specific effects of C3-mediated neurodegeneration
Generation and characterization of C3 inducible conditional KO Alzheimer’s-like mice
Sinkovits György C1-INH complexes as markers for classical and lectin pathway activation
Sironi Marina The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Skjoedt Mikkel-Ole The complement regulator MAP-1 interacts with activated FXII and attenuates the coagulation system
Smiesko Martin Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Smith Deane Xenotransplantation: Using Genome Editing to Overcome Pig-to-Human Incompatibilities.
Smith-Jackson Kate An Oral C5aR receptor antagonist blocks disease in the C3 gain-of-function mouse model of aHUS.
Spooner Emma A MaGical cASe: a story on the cell-specific effects of C3-mediated neurodegeneration
Generation and characterization of C3 inducible conditional KO Alzheimer’s-like mice
Stern Jeffrey Xenotransplantation: Using Genome Editing to Overcome Pig-to-Human Incompatibilities.
Stravalaci Matteo Involvement of PTX3 and MBL in the clearance of SARS-CoV-2 infected lung airway epithelial cells
The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Szebeni Janos The COVID-19 mRNA vaccine Comirnaty induces anaphylactic shock in an anti-PEG hyperimmune pig model: Role of complement activation in cardiovascular, hematological and inflammatory mediator changes
Tannenbaum Steven R. Aberrant protein S-nitrosylation of C3 activates phagocytosis of neuronal synapses by microglia in Alzheimer's disease
Taylor Ronald FcγR-mediated Trogocytosis 2.0: Revisiting History gives rise to a Unifying Hypothesis
Tenner Andrea New Shot on Goal: Targeting Inflammation and Synapse Loss to Suppress Alzheimer’s Disease
Teramura Yuji An alternative binding and activation mechanism of native C3 induced by contact with biosurfaces without involvement of the thioester
Theisen Erin Granzyme K activates a new complement pathway
Thomas Julie Age-related Macular Degeneration: a Tale of Two RPE-centric Diseases, of Which Only One is Complement-driven
Thompson Emily Evaluation of minimal factor H therapy administered to kidneys during ex vivo normothermic perfusion as a treatment to improve ischaemia reperfusion injury
Tingle Samuel Evaluation of minimal factor H therapy administered to kidneys during ex vivo normothermic perfusion as a treatment to improve ischaemia reperfusion injury
Tomlinson Stephen The immune cell landscape of the injured brain and its relation to the complement system in traumatic brain injury
Natural antibody targeted complement inhibitor ameliorates the development of chronic heart and lung transplant rejection
Toonen Erik C1-INH complexes as markers for classical and lectin pathway activation
Toutonji Amer The immune cell landscape of the injured brain and its relation to the complement system in traumatic brain injury
Trudler Dorit Aberrant protein S-nitrosylation of C3 activates phagocytosis of neuronal synapses by microglia in Alzheimer's disease
Tschongov Todor Glycan structure optimization of moss produced human complement factor H markedly improves pharmacokinetic and pharmacodynamics properties in vivo.
Tu Zhenxiao Natural antibody targeted complement inhibitor ameliorates the development of chronic heart and lung transplant rejection
Umnyakova Ekaterina Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
van Bree Bregje C1-INH complexes as markers for classical and lectin pathway activation
Van de Walle Inge Complement inhibition prevents paranodal loop injury in an anti-GM1 antibody-mediated paranodal demyelinating mouse model.
Vicenzi Elisa Involvement of PTX3 and MBL in the clearance of SARS-CoV-2 infected lung airway epithelial cells
The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Vogt Stephanie Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Weber Lukas Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy
Widmer Kevin Drug and Druggability: A new era in complement-targeted therapeutics and novel approaches off the conventional path
Williams Brandi Age-related Macular Degeneration: a Tale of Two RPE-centric Diseases, of Which Only One is Complement-driven
Willison Hugh Complement inhibition prevents paranodal loop injury in an anti-GM1 antibody-mediated paranodal demyelinating mouse model.
Wilson Colin Evaluation of minimal factor H therapy administered to kidneys during ex vivo normothermic perfusion as a treatment to improve ischaemia reperfusion injury
Wishnok John S. Aberrant protein S-nitrosylation of C3 activates phagocytosis of neuronal synapses by microglia in Alzheimer's disease
Woodruff Trent Identification of genes involved in the protective response of C3aR in amyotrophic lateral sclerosis pathology
A detrimental role for complement C5aR1 activation in Huntington’s disease
Würzner Reinhard C1-INH complexes as markers for classical and lectin pathway activation
Yancopoulou Despina Mechanistic and therapeutic aspects in complement-driven periodontal disease
A new treatment paradigm for Paroxysmal Nocturnal Hemoglobinuria: the era of proximal complement inhibitors
Probing C3 modulation in the intracellular space: Cellular internalization of compstatin-based C3 inhibitors and its functional implications
Yang Zhansheng Immunopathology of Terminal Complement Activation and Complement C5 Blockade Creating a Pro-survival and Organ-protective Phenotype in Trauma
Aberrant protein S-nitrosylation of C3 activates phagocytosis of neuronal synapses by microglia in Alzheimer's disease
Yao Denggao Complement inhibition prevents paranodal loop injury in an anti-GM1 antibody-mediated paranodal demyelinating mouse model.
Zelek Wioleta The role of terminal pathway in driving pathology in dementia.
Zhang Ying Continued investigations of modified DNA aptamers as inhibitors of complement proteins and their complexes
Zhong Hang Involvement of PTX3 and MBL in the clearance of SARS-CoV-2 infected lung airway epithelial cells
The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Zoia Elena The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
Zouache Moussa Age-related Macular Degeneration: a Tale of Two RPE-centric Diseases, of Which Only One is Complement-driven