Aegean Conferences

4th International Conference on Oral Mucosal Immunity and Microbiome

Program

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General Information

No details.

Sunday, October 12

06:00 PM - 07:00 PM

Conference Registration

07:00 PM - 10:00 PM

Welcome Reception and Dinner

Monday, October 13

08:00 AM - 08:45 AM

Breakfast

08:45 AM - 09:00 AM

Welcome and Opening Remarks - George Belibasakis

Microbial pathogenesis

Chairs: George Hajishengallis and Shannon Wallet

09:00 AM - 09:20 AM

Coordination of metabolism and virulence by Porphyromonas gingivalis
Richard Lamont

09:20 AM - 09:40 AM

OncoGlycan preference of Fusobacterium nucleatum
Bachrach Gilad¹, Ofir Rokach-Ventura², Tamar Alon-Miamon¹, lei xia1³, Arielle Jacover³, Yehuda Shovman³, Nicole Haj¹, Reem Bsoul¹, Viviana Scaiewicz¹, Shani Leviatan Ben-Arye², Vered Padler-Karavani², and Oren Parnas³

09:40 AM - 10:00 AM

Virion stripping - a new role for P. gingivalis proteases
Juhi Bagaitkar

10:00 AM - 10:20 AM

Sabotaged by precision: Neutrophil versatility and bacterial evasion
Silvia Uriarte

10:20 AM - 10:40 AM

Deciphering the mysteries of Filifactor alocis
George Belibasakis

10:40 AM - 11:00 AM

Zuzalysins, a New Kids on the Block: Unique Zinc-metallopeptidases (Family M97) in Bacteroidota's Species Biology and Pathogenicity
Zuzanna Nowakowska¹, Danuta Mizgalska¹, Mariusz Madej¹, Borys Szmigielski¹, Guillem Ylla Bou¹, Arturo Rodríguez Banqueri², F. Xavier Gomis-Rüth², and Jan Potempa¹

11:00 AM - 11:45 AM

Coffee Break and Poster Viewing (Odd Numbers)

Oral disease and comorbidities

Chairs: Juhi Bagaitkar and Gilad Bachrach

11:45 AM - 12:05 PM

Causative links between periodontal disease and comorbidities
George Hajishengallis

12:05 PM - 12:25 PM

SP140 as a Master Regulator of Immune Reprogramming in the Oral Tumor Microenvironment
Fatemeh Momen-Heravi

12:25 PM - 12:45 PM

Oral Inflammation and Microbiome in Rheumatoid Arthritis
Hatice Hasturk

12:45 PM - 01:05 PM

Porphyromonas gingivalis infected antigen-presenting cells: A novel model to identify arthritis-provoking CD4 T cells (?)
Jennifer Malcolm

01:05 PM - 01:25 PM

Microbiome Signatures Associated with M-MDSC Expansion in Obesity and Periodontal Disease
Keith L Kirkwood

01:25 PM - 01:45 PM

Systemic and Chronic Oral Inflammatory Pathways in HIV
Modupe Coker

01:45 PM - 03:00 PM

Lunch and Informal Discussions

03:00 PM - 07:00 PM

Informal Discussions

07:30 PM - 11:00 PM

Dinner and Informal Discussions (Buses Depart from Hotel Lobby)

Tuesday, October 14

08:00 AM - 09:00 AM

Breakfast

Oral Microbiome

Chairs: Silvia Uriarte and Tomoki Maekawa

09:00 AM - 09:20 AM

Machine learning pipeline identifies population-level subgingival microbiome states linked to periodontitis phenotypes and host factors
Patricia I Diaz and Lu Li

09:20 AM - 09:40 AM

Spatially-resolved bacterial single-cell RNA sequencing links microbe-microbe interactions and transcriptional heterogeneity
Marvin Whiteley

09:40 AM - 10:00 AM

Exploring the Role of Type VI Secretion in the Oral Cavity
Nagihan Bostanci

10:00 AM - 10:20 AM

Modeling, modulating and quantifying oral microbial dysbiosis
Nezar Al-hebshi

10:20 AM - 10:40 AM

Insights into low-abundance members of the oral microbiome
Thuy Do¹, Naile Dame-Teixeira², Jack Lynch¹, Xia Yu¹, and Jessica Cena²

10:40 AM - 11:00 AM

The Oral Resistome in Healthy Individuals from two geographic locations with differences in antibiotic use: A Comparative Metagenomic Study.
Mohammed Al-Haroni^1,², Supathep Tansirichaiya^2,³, Kittikun Songsomboon⁵, Nichamon Chaianant⁴, Wasawat Lertsivawinyu³, Johannes Wigand², and Endre Winje²

11:00 AM - 11:45 AM

Coffee Break and Poster Viewing (Even Numbers)

Oral health and disease

Chairs: Flora Momen-Heravi and Julie Marchesan

11:45 AM - 12:05 PM

Neutrophil Subtypes in Periodontitis: From Inflammation to Bone Loss
Marjolaine Gosset, Jérome Bouchet, Shengyi Lu, and Banndith Cheat

12:05 PM - 12:25 PM

Proteolytic activity, microbial and host proteome signatures in gingival crevicular fluid from patients with periodontitis.
Miguel Carda-Dieguez², Stefan Rüdiger³, Yashuan Chao ¹, Alex Mira², Oonagh Shannon¹, Tirthankar Mohanty⁴, Johan Malmström⁴, and Julia Davies¹

12:25 PM - 12:45 PM

Nitrate metabolism by the oral microbiota in periodontal health and disease
Bob T. Rosier

12:45 PM - 01:05 PM

Omics studies elucidate the contribution of immune dysregulation to the pathogenesis of periodontitis
Pirkko Pussinen

01:05 PM - 01:25 PM

B cells safeguard the integrity of the gingival barrier
Shahd Yacoub^1,² and Avi-Hai Hovav^1,²

01:25 PM - 01:45 PM

Unique spatial organization promotes local immunity at the oral barrier
Drake Williams

01:45 PM - 02:05 PM

Novel Therapeutic Strategies for Bone Loss in Periodontitis and Aging: The Potential of DEL-1
Tomoki Maekawa

02:05 PM - 03:30 PM

Lunch and Informal Discussions

03:30 PM - 07:00 PM

Informal Discussions

07:30 PM - 11:00 PM

Dinner and Informal Discussions (Buses Depart from Hotel Lobby)

Wednesday, October 15

08:00 AM - 09:00 AM

Breakfast

Host-microbe interactions

Chairs: Patricia Diaz and Drake Williams

09:00 AM - 09:20 AM

Uncovering the Role of Mutanofactins in Oral Biofilm Formation: A Molecular Insight into Streptococcus mutans and Mucin Interactions
Leon S.G. Thies¹, Konstantin N. Beitl¹, Muhammad Afzal¹, Lukas Lüthy², Susanne Bloch¹, Fiona F. Hager-Mair¹, Alex Mira³, Erick M. Carreira², Erik Reimhult¹, and Chrsitina Schäffer¹

09:20 AM - 09:40 AM

Boosting oral defense: Streptococcus sanguinis membrane vesicles safeguard gingival epithelial cells
Jens Kreth

09:40 AM - 10:00 AM

Biomarkers of Host-Microbe Interaction in Periodontal Healing
Ulvi K Gursoy

10:00 AM - 10:20 AM

Oral Host-Microbiome Interactions; some examples using a complex in vitro model
Bastiaan P. Krom

10:20 AM - 10:40 AM

Pathogen Synergy and Immune Subversion in Periodontitis
Courtney Jennings and Apollo Stacy

10:40 AM - 11:00 AM

Development of a selective inhibitor for Porphyromonas gingivalis
Akintunde Emiola

11:00 AM - 11:45 AM

Coffee Break and Poster Viewing (Odd Numbers)

Current topics in oral science

Chairs: Youngnim Choi and Nezar Al-hebshi

11:45 AM - 12:05 PM

Diabetes enhances periodontitis by activating the CD137L-CD137 axis in dendritic and γδ T-cells
Dana Graves¹, Xin Huang ^1,³, Min Liu¹, Michael Gonzalez ², Hamideh Afzali ¹, and Kang Ko¹

12:05 PM - 12:25 PM

From Microbial Myths to Clinical Milestones Through Probiotics
Wim Teughels

12:25 PM - 12:40 PM

Mechanisms of corncob formation
Ross Garrison¹, Kenneth L Brockman³, and Samantha J King^1,²

12:40 PM - 12:55 PM

Exploring fatty acid metabolism in Streptococcus to guide therapeutic development
Jonathon L Baker

12:55 PM - 01:10 PM

Oral Microbial Resilience to Estradiol Variations: In Vivo and In Vitro Evidence
Maria J Rus¹, Ana T Marcos², Victoria Areal-Quecuty¹, Thuy Do³, Jack Lynch³, David Alarcón-Alarcón⁴, José Manuel Navarro-Pando², and Aurea Simon-Soro¹

01:10 PM - 01:25 PM

Shotgun metagenomic profiling of multi-kingdom oral microbiome in periodontal health and diseases
Susanna Paju¹, Jaakko Leskelä¹, Eija Könönen², Leo Lahti³, Jukka Putaala⁴, Pirkko Pussinen^1,⁵, and Muhammed Manzoor¹

01:25 PM - 01:40 PM

Unveiling the Role of Granulicatella adiacens Extracellular Vesicles in Infection: Proteomic and Functional Insights from Biofilm and Planktonic States
Maribasappa Karched¹ and Sarah Alkandari²

01:40 PM - 01:55 PM

Genomic characterization of canine ‘Treponema denticola-like’ isolates
Rory M Watt¹, Yuki Chan¹, and Huihui Zeng²

01:55 PM - 03:00 PM

Lunch and Informal Discussions

03:00 PM - 08:00 PM

City Tour of Chania (Buses Depart Hotel Lobby)

08:00 PM - 11:00 PM

Dinner and Informal Discussions (Buses do not return or pickup from the hotel prior to dinner)

Thursday, October 16

08:00 AM - 09:00 AM

Breakfast

Host immunity and regulation

Chairs: Jan Potempa and Georgios Belibasakis

09:00 AM - 09:20 AM

Trained immunity in inflammatory disease
Triantafyllos Chavakis

09:20 AM - 09:40 AM

Lymphocyte apoptosis and impaired type-17 immunity underlie mucosal candidiasis in DOCK8 deficiency and can be rescued by IL-7 immunotherapy
Michail Lionakis

09:40 AM - 10:00 AM

B cells function as innate antigen-presenting cells through BCR-independent bacterial uptake
Youngnim Choi

10:00 AM - 10:20 AM

The Impact of Clonal Hematopoiesis on Periodontitis
Hui Wang

10:20 AM - 10:40 AM

Oral antiviral T cell responses and taste
Michael Stolley

10:40 AM - 10:55 AM

Extracellular vehicles: regulators of immune modulation
Madelyn Bucci^1,², Denise Hernandez^1,², Micah Willis¹, Robert Maile², and Shannon Wallet¹

10:55 AM - 11:45 AM

Coffee Break and Poster Viewing (Even Numbers)

Bone loss: mechanisms and treatment

Chairs: Nagihan Bostanci and Samantha King

11:45 AM - 12:05 PM

New Frontiers in Osteoimmunology
Masayuki Tsukasaki

12:05 PM - 12:25 PM

IL-22 synergizes with IL-17 to promote mucosal inflammation and bone loss
Xiaofei Li¹ and George Hajishengallis²

12:25 PM - 12:45 PM

The Inflammasome drives a sex-bias in periodontitis
Julie T Marchesan

12:45 PM - 01:00 PM

Reduced osteoprotegerin production impairs the ability of gingival fibroblasts from periodontitis patients to inhibit osteoclastogenesis.
Elwira Nieboga¹, Jan Potempa², and Aleksander M Grabiec¹

01:00 PM - 01:15 PM

Therapeutic Effects of Chios Mastic on the Oral Microbiome in Gingivitis and Early Periodontitis
Filippos S. Kardaras^1,², William Papaioannou³, Chrysoula Giota^4,⁵, Efthymios Skaribas^4,⁵, Beatriz Martinez-Gonzalez⁶, Dionyssios N. Sgouras⁶, and Artemis G. Hatzigeorgiou^1,²

01:15 PM - 01:30 PM

Osteoimmune Disruption in MRONJ: Interplay Between Antiresorptive Therapy, Bone Remodeling, and Antimicrobial Peptides
Linus Winter¹, Stella Luckey², Agnus Monica Davis², Annika Haeuser², Sofia Hutter², Cornelia Stoll², Alexandra Correa Zamora², Stefan Uderhardt², Manuel Weber¹, Georg Schett², Marco Kesting¹, and Carina Scholtysek²

01:30 PM - 01:45 PM

Host defense against oral cancer invasion by the periosteum
Kazutaka Nakamura¹, Masayuki Tsukasaki¹, Kazuto Hoshi², and Hiroshi Takayanagi³

01:45 PM - 01:50 PM

Closing Remarks - George Hajishengallis

01:50 PM - 03:30 PM

Lunch and Informal Discussions

03:30 PM - 07:30 PM

Informal Discussions

07:30 PM - 11:00 PM

Farewell Dinner

Friday, October 17

08:00 AM - 10:00 AM

Breakfast

10:00 AM - 12:00 PM

Departure