6th International Conference on Stem Cells

Program

Important: The program online is copyrighted to each author and should not be copied and pasted!
  • Aegean Conferences Communication  

    Please note that our registration fees include hotel accommodations and therefore no additional reservations are required. The only communication you should receive is from Aegean Conferences and if your paying by credit card, payment receipts from Conferex LLC. SCAM Alert: Beware of any third party companies calling and/or emailing you to reserve hotel accommodations for you during our conferences

    Registration 
    In completing the online registration form you are not automatically accepted to attend the conference nor are you automatically registered for the conference. Final registration to the conference shall occur after you have been accepted and notified by the conference chair of your acceptance to the conference. If you have been charged the registration fee but your attendance has been declined you will be reimbursed in full. Disclaimer: Meetings are intended for invited participants only. While we do not restrict the attendance of participant family members at the meeting venues, please note that all scheduled events and activities are designed for adults only. We kindly ask that guests respect the intended audience to ensure a focused and professional environment.

    Airport
    Please note that Crete has two airports. You want to arrive at the Heraklion International Airport (code: HER) and take a taxi from the airport to the hotel (~65 EUR). You may also rent a car at the airport and drive to the conference center. Alternatively Chania International Airport (CHQ) is a two-hour drive to the Conference Center.

    Accommodation Tax
    An accommodation tax of € 15.00 per room night will apply, and will be charged automatically to the individual guest’s extras accounts. 

    Accommodations
    Accommodations for the conference are at the Kalimera Kriti Hotel.  The hotel is located in Sissi, 40 km from Heraklion International Airport.  Please take a taxi from the airport to the conference venue. 

    Arrival and Check-in 
    It is expected that attendees will arrive/check-in after 2:00 PM. Anyone arriving after 10:00 pm on the first day should make alternative dinner arrangements.

    Conference Venue
    The Kalimera Kriti Conference Center is located at the hotel. 

    Handicapped Accessibility
    The site is fully handicapped accessible.

    Oral Presentations
    Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session.  The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A.

    Archaeological Site of Knossos and City Tour
    Buses for the city tour will depart from the hotel front lobby at 3:00 pm. Badges are required for participation. 

    Breakfast
    Breakfast for registered participants and registered accompanying persons will be served at the Kalimera Kriti main restaurant during the hours scheduled in this program. 

    Lunches/Informal Discussions
    Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant and only after the session has finished. Badges are required for admission.

    Dinners/Informal Discussions
    Three of the dinners/informal discussion will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting.  Please contact info@aegeanconferences.org. 

    Vegetarian Meals / Food Allergies
    Please note that only vegetarian meal options can be accommodated for this event. While we strive to ensure quality and safety, due to potential cross-contamination and the inability to verify the food preparation standards of third-party restaurants, the company cannot guarantee that meals will meet specific dietary restrictions beyond vegetarian offerings. The company also cannot be held responsible for food safety or allergen exposure, as we are unable to fully vet the kitchens or practices of the venues selected for event outings.

    Internet, Phone, & Computer 
    Wireless Internet access is located throughout the conference center free of charge during meeting hours. There are computers available in the hotel’s business center for the use of the attendees. Phone service is available for an additional charge from your hotel room.

    Certificate of Participation
    A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session. 

    Passports and Visa/ETIAS
    Participants are advised to check on their individual requirements before attending any Aegean Conference meeting. Visa applications should be filed at the nearest Greek Embassy in the country in which you are resident, at least three months prior to the anticipated departure date. Starting 2025 you may need to apply for an ETIAS.
    https://www.etiaseu.com/us-citizens/etias-greece

    Letters of Invitation
    Letters of invitation to attend an Aegean Conference meeting will be issued only to:

    • Authors of accepted abstracts
    • Fully paid registrants

    Note: Invitations are issued at the discretion of Aegean Conferences, and requests for letters will be accepted only 60 days prior to the conference start date.

    Liability and Insurance
    Neither the organizers, nor the Aegean Conferences will assume any responsibility whatsoever for damage or injury to persons or property during meeting period. Participants are advised to arrange their own personal travel and health insurance.  

    Other Information
    Animals are not permitted on site.
    Badges are required for admission to all events.
    All Aegean Conferences events are no smoking, no e-cigarretes, no vaping, etc. 

    No Photographs and Recording Devices 
    Participants are not allowed to photograph and/o

Wednesday, October 01

06:00 PM - 07:30 PM
Conference Registration
07:30 PM - 10:00 PM
Welcome Reception and Dinner

Thursday, October 02

08:00 AM - 08:30 AM
Breakfast
08:30 AM - 08:40 AM
Welcome and Opening Remarks - Jeffrey Dilworth
Session 1
Chairs: Meng-Wei Ko and Jeffrey Dilworth
08:40 AM - 09:00 AM
1
Next generation cell therapies for the brain
Marius Wernig
09:00 AM - 09:20 AM
2
iPSC-based functional genomics approaches to unravel coronary artery disease risk
Valentina Lo Sardo
09:20 AM - 09:40 AM
3
Organotypic disease modelling and therapeutic development for tuberous sclerosis complex
Bill Stanford
09:40 AM - 09:55 AM
4
A Scalable Microarrayed Organoid Platform for Precision Modeling of Intestinal Epithelial Damage and Recovery
Omid Mashinchian
09:55 AM - 10:15 AM
5
Distinct roles of Notch signaling in muscle grafts from pluripotent stem cells
Aline MS Yamashita and Rita CR Perlingeiro
10:15 AM - 10:35 AM
6
Mechano-Epigenetic Regulation for Enhanced Musculoskeletal Tissue Regeneration
Su Chin Heo
10:35 AM - 11:15 AM
Coffee Break and Poster Viewing (Odd Numbers)
Session 2
Chairs: Jeremie Rispal and April Pyle
11:15 AM - 11:45 AM
7
Connie Eaves Lecture: Tracking the origins of human hematopoietic and leukemic stem cells
Hanna Mikkola
11:45 AM - 12:05 PM
8
Transcriptional regulation of hepatobiliary identity in liver development and regeneration
Adam D Gracz
12:05 PM - 12:25 PM
9
Modeling Human Development Beyond Implantation Using Integrated Stem Cell-Derived Embryo Models
Magdalena Zernicka-Goetz
12:25 PM - 12:40 PM
10
Epigenetic basis for mesenchymal diversification during intestinal development
Swarnabh Bhattacharya, Guodong Tie, Debanjan Barua, and Ramesh A Shivdasani
12:40 PM - 01:00 PM
11
Defining spatial niche acquisition in human myogenesis
April Pyle
01:00 PM - 01:20 PM
12
Regeneration in the Uterus
Kara McKinley
01:20 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Dinner and Informal Discussions (Buses Depart from Hotel Lobby)

Friday, October 03

08:00 AM - 08:30 AM
Breakfast
Session 3
Chairs: Valentina Taglietti and Ophir Klein
08:30 AM - 08:50 AM
13
Diversity and dynamics of muscle stem and niche cells
Shahragim Tajbakhsh
08:50 AM - 09:10 AM
14
Organ-level regeneration in mammals: Lessons from skin wounds
Ya-Chieh Hsu
09:10 AM - 09:30 AM
15
Aging by Fire: How Inflammation and Iron Drive Epigenetic Erosion and Ferroptotic Vulnerability in Stem Cells
Roméo S Blanc
09:30 AM - 09:45 AM
16
Investigating the role of the endothelial cell niche in intestinal regeneration and disease
Brisa Palikuqi
09:45 AM - 10:05 AM
17
Molecular mechanism of stem cell regulation in epidermis and hair follicle
Tudorita Tumbar
10:05 AM - 10:25 AM
18
Decoding the molecular cues that regulate HSC specification
David Traver
10:25 AM - 10:45 AM
19
Making sense of adult neural stem cell heterogeneities
Laure Bally-Cuif
10:45 AM - 11:30 AM
Coffee Break and Poster Viewing (Even Numbers)
Session 4
Chairs: Amanda Collier and Frederic Relaix
11:30 AM - 11:50 AM
20
Tissue-derived organoids: where we stand and where we go
Meritxell Huch
11:50 AM - 12:10 PM
21
Targeting Altered RNA Processing in Malignant Hematopoietic Stem Cells
Kristin Hope
12:10 PM - 12:25 PM
22
Enhancing Digit Regeneration Through Nail Mini-Organ Stem Cell Activation
Anna Maria Pulawska-Czub, Alicja Olczak-Cossu, Tomasz Pieczonka, and Krzysztof Kobielak
12:25 PM - 12:45 PM
23
Developing a robust injury model to investigate the role of intestinal repair during development.
Andrew Sanchez and Benjamin Ohlstein
12:45 PM - 01:05 PM
24
Extra-telomeric key functions shape muscle stem cells fate and tissue regeneration
Foteini Mourkioti
01:05 PM - 01:20 PM
25
Microbiome-produced nicotinic acid controls colon regional identity and injury susceptibility
Jeremie Rispal
01:20 PM - 01:40 PM
26
Teratoma-derived myogenic progenitors for human skeletal muscle grafts
Michael Kyba
01:40 PM - 03:00 PM
Lunch and Informal Discussion
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Dinner and Informal Discussions (Buses Depart from Hotel Lobby)

Saturday, October 04

08:00 AM - 08:30 AM
Breakfast
Session 5
Chairs: Andreea Cojocaru and Foteini Mourkioti
08:30 AM - 08:50 AM
27
Human-specific regulatory mechanism revealed in a 3D embryo model
Raquel Fueyo, Sicong Wang, Olivia J. Crocker, Tomek Swigut, Hiromitsu Nakauchi, and Joanna Wysocka
08:50 AM - 09:10 AM
28
Single-cell trimodal study of cell fate decisions in hematopoiesis and leukemogenesis
Marjorie Brand
09:10 AM - 09:30 AM
29
Dietary Control of Stem Cells in Physiology and Disease
Omer Yilmaz
09:30 AM - 09:45 AM
30
Distinct regenerative properties of Extra-ocular muscle mesenchymal stromal cells support muscle stem cell maintenance
Valentina Taglietti1, Andreea Cojocaru1, Laurent Tiret2, Daniel Helzer3, Rachelle Crosbie3, Benedicte Chazaud4, Antonio Moretta4, and Frederic Relaix1
09:45 AM - 10:05 AM
31
Why do human haematopoietic stem cells lose function ex vivo?
Elisa Laurenti
10:05 AM - 10:25 AM
32
Generating Bespoke Chimeric Brains From the Blastocyst
Kristin Baldwin
10:25 AM - 10:45 AM
33
Mechanisms regulating stem cell plasticity during tumor initiation
Cédric Blanpain
10:45 AM - 11:30 AM
Coffee Break and Poster Viewing (Odd Numbers)
Session 6
Chairs: John Nguyen and Omer Yilmaz
11:30 AM - 11:50 AM
34
Hoxa11/Hoxd11 Function is Required for Hh Signaling Response in Skeletal Stem Cells
Deneen Wellik
11:50 AM - 12:10 PM
35
PAX3 drives muscle stem cell functional heterogeneity during muscle repair
Fred Relaix
12:10 PM - 12:25 PM
36
Building better blastoids: Generating high-fidelity human embryo models
Amanda J Collier1, Peter Chovanec2, Shouzheng Yue3,4, Abigail S Krall1, Franziska Heinkele1, Jihui Sha1, Immy Ashley5,6, Ruby A Sims3,4, Liudmilla Rubbi7, Benjamin Feng1, Youngsun Hwang7, Amander T Clark7, Matteo Pellegrini7, Heather R Christofk1, Mehdi Bouhaddou5,6, Yi Yin2, James A Wohlschlegel1, Steven J Jonas3,4, and Kathrin Plath1
12:25 PM - 12:45 PM
37
NON-canonical roles of the Keap1/Nrf2 axis in regulating quiescence and early activation in adult muscle stem cells
Zhenguo Wu
12:45 PM - 01:05 PM
38
Uncovering Cellular Crosstalk in the Pancreatic Islet Using Multicellular Organoids
Maike Sander
01:05 PM - 01:20 PM
39
Synchronized Oscillation of the Common Core Gene Network Regulated by the BMP-ID2 Axis Determines Cyclic Regeneration and Resting Phases in Hair Follicle Stem Cells.
Lukasz Boryn1, Patrycja Daszczuk1, Xiaoyang Wang2, Konrad Lukaszyk1, Ajay Jakhar1, Paula Mazurek1, Alicja Olczak1, Tomasz Pieczonka1, Guangfang Wang2, Raul Ramos2, Xiaojie Wang2, Agnieszka Kobielak1, Maksim Plikus2, Mark Israel3, Yun Kyuson4, and Krzysztof Kobielak1
01:20 PM - 01:40 PM
40
Stem cell aging: Evolutionary trade-offs and survivorship bias
Thomas Rando
01:40 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Archaeological Tour of Knossos and the Museum (Buses Depart Hotel Lobby)
08:00 PM - 11:00 PM
Dinner and Informal Discussions (Buses do not return to the hotel prior to dinner)

Sunday, October 05

08:00 AM - 08:30 AM
Breakfast
Session 7
Chairs: Anna Pulawska-Czub and Hanna Mikkola
08:30 AM - 08:50 AM
41
Renewal and plasticity in gastrointestinal epithelia
Ophir Klein
08:50 AM - 09:10 AM
42
Modulating cellular plasticity to promote tissue repair in intestinal disease
Helen E Abud1,2,3, Diana Micati1,2, Shanika Amarasinghe1,2, Khan Ha Do1,2, Andrew Pattison1,2, Stuart Archer1,2, Lucy Porter1,2, Paul J McMurrick3, Edward Giles4,5, and Thierry Jarde1,2,3
09:10 AM - 09:30 AM
43
Live Imaging of Alveolar Stem Cells and their Fibroblast Niche
Nan Tang
09:30 AM - 09:45 AM
44
Epithelial-mesenchymal cell competition coordinates fate transitions across tissue compartments during lung development and fibrosis.
Kylie Klinkhammer, Rachel Warren, Joseph Knopp, Toan Nguyen, and Stijn De Langhe
09:45 AM - 10:05 AM
45
HERVHLin modulates pluripotency and protects the genome from mutagenic retroelements by rewiring the conserved LIN28A/let-7 pathway in the early human embryo
Zsuzsanna Izsvak1, Aleksandra M Kondrashkina1, Manvendra Singh1, Egor Semenchenko1, Amit Pande1, Jose l Garcia-Perez2, and Laurence D Hurst3
10:05 AM - 10:25 AM
46
Epigenetic control of fate decisions in muscle regeneration
Jeff Dilworth
10:25 AM - 10:45 AM
47
Stromal regulation of tissue repair
Valerie Horsley
10:45 AM - 11:25 AM
Coffee Break and Poster Viewing (Even Numbers)
Session 8
Chairs: Candaice Newell and Valentina Lo Sardo
11:25 AM - 11:45 AM
48
Expanding Stem Cell-Based Cell and Gene Therapy Combinations for Treating Degenerative Diseases and Beyond
Andras Nagy
11:45 AM - 12:05 PM
49
Live Tracing Reveals Regenerative Plasticity and Dysfunction in the Corneal Niche
Ruby Shalom-Feuerstein
12:05 PM - 12:25 PM
50
Refining astrocyte-to-neuron reprogramming specificity via microRNA-guided neuronal detargeting
Hussein Ghazale1,2, Martin Parga Pazos3, Sascha Jung3, Ke Cao1, Lakshmy Vasan1, Jack W Hickmott7, Linghe Zhang1, Cindi M Morshead7, Chao Wang1, Antonio del Sol9, and Carol Schuurmans1,2
12:25 PM - 12:40 PM
51
Polyamine metabolism regulates muscle stem cell and fibro-adipogenic progenitor proliferation and differentiation during skeletal muscle regeneration
John H Nguyen1, Kristy Swiderski1, Kristin K Brown2, Robert N Judson4, Amy J Bongetti1, Jin D Chung5, Jennifer Trieu1, Annabel Chee1, Paul Gregorevic1, David P De Souza6, René Koopman1, Craig A Goodman1, and Gordon S Lynch1
12:40 PM - 01:00 PM
52
A machine learning-based computational platform for cellular conversion to generate functionally mature cells - an application on corticospinal neurons
Antonio del Sol
01:00 PM - 01:20 PM
53
Epigenetic regulation of epithelial cell plasticity in tissue regeneration and immunity
Semir Beyaz
01:20 PM - 01:30 PM
Closing Remarks - Jeffrey Dilworth
01:30 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Farewell Dinner

Monday, October 06

08:00 AM - 10:00 AM
Breakfast
10:00 AM - 12:00 PM
Departure