Wednesday, October 01
06:00 PM - 07:30 PM
Conference Registration
07:30 PM - 10:00 PM
Welcome Reception and Dinner
Thursday, October 02
08:00 AM - 08:30 AM
Breakfast
08:30 AM - 08:40 AM
Welcome and Opening Remarks - Jeffrey Dilworth
Chairs: Meng-Wei Ko and Jeffrey Dilworth
08:40 AM - 09:00 AM
1
Next generation cell therapies for the brainMarius Wernig
09:00 AM - 09:20 AM
2
iPSC-based functional genomics approaches to unravel coronary artery disease riskValentina Lo Sardo
09:20 AM - 09:40 AM
3
Organotypic disease modelling and therapeutic development for tuberous sclerosis complexBill Stanford
09:40 AM - 09:55 AM
4
A Scalable Microarrayed Organoid Platform for Precision Modeling of Intestinal Epithelial Damage and RecoveryOmid Mashinchian
09:55 AM - 10:15 AM
5
Distinct roles of Notch signaling in muscle grafts from pluripotent stem cellsAline MS Yamashita and Rita CR Perlingeiro
10:15 AM - 10:35 AM
6
Mechano-Epigenetic Regulation for Enhanced Musculoskeletal Tissue RegenerationSu Chin Heo
10:35 AM - 10:55 AM
7
Defining spatial niche acquisition in human myogenesisApril Pyle
10:55 AM - 11:30 AM
Coffee Break and Poster Viewing (Odd Numbers)
Chairs: Jeremie Rispal and April Pyle
11:30 AM - 12:00 PM
8
Connie Eaves Lecture: Tracking the origins of human hematopoietic and leukemic stem cellsHanna Mikkola
12:00 PM - 12:20 PM
9
Transcriptional regulation of hepatobiliary identity in liver development and regenerationAdam D Gracz
12:20 PM - 12:40 PM
10
Modeling Human Development Beyond Implantation Using Integrated Stem Cell-Derived Embryo ModelsMagdalena Zernicka-Goetz
12:40 PM - 12:55 PM
11
Epigenetic basis for mesenchymal diversification during intestinal developmentSwarnabh Bhattacharya, Guodong Tie, Debanjan Barua, and Ramesh A Shivdasani
12:55 PM - 01:15 PM
12
Single-cell trimodal study of cell fate decisions in hematopoiesis and leukemogenesisMarjorie Brand
01:15 PM - 01:35 PM
13
Regeneration in the UterusKara McKinley
01:35 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Dinner and Informal Discussions (Buses Depart from Hotel Lobby)
Friday, October 03
08:00 AM - 08:30 AM
Breakfast
Chairs: Valentina Taglietti and Ophir Klein
08:30 AM - 08:50 AM
14
Diversity and dynamics of muscle stem and niche cellsShahragim Tajbakhsh
08:50 AM - 09:10 AM
15
Organ-level regeneration in mammals: Lessons from skin woundsYa-Chieh Hsu
09:10 AM - 09:30 AM
16
Aging by Fire: How Inflammation and Iron Drive Epigenetic Erosion and Ferroptotic Vulnerability in Stem CellsRoméo S Blanc
09:30 AM - 09:45 AM
17
Investigating the role of the endothelial cell niche in intestinal regeneration and diseaseBrisa Palikuqi
09:45 AM - 10:05 AM
18
Molecular mechanism of stem cell regulation in epidermis and hair follicleTudorita Tumbar
10:05 AM - 10:25 AM
19
Decoding the molecular cues that regulate HSC specificationDavid Traver
10:25 AM - 10:45 AM
20
Making sense of adult neural stem cell heterogeneities Laure Bally-Cuif
10:45 AM - 11:30 AM
Coffee Break and Poster Viewing (Even Numbers)
Chairs: Amanda Collier and Frederic Relaix
11:30 AM - 11:50 AM
21
Tissue-derived organoids: where we stand and where we goMeritxell Huch
11:50 AM - 12:10 PM
22
Targeting Altered RNA Processing in Malignant Hematopoietic Stem Cells
Kristin Hope
12:10 PM - 12:25 PM
23
Enhancing Digit Regeneration Through Nail Mini-Organ Stem Cell Activation Anna Maria Pulawska-Czub, Alicja Olczak-Cossu, Tomasz Pieczonka, and Krzysztof Kobielak
12:25 PM - 12:45 PM
24
Developing a robust injury model to investigate the role of intestinal repair during development.
Andrew Sanchez and Benjamin Ohlstein
12:45 PM - 01:05 PM
25
Extra-telomeric key functions shape muscle stem cells fate and tissue regenerationFoteini Mourkioti
01:05 PM - 01:20 PM
26
Microbiome-produced nicotinic acid controls colon regional identity and injury susceptibility Jeremie Rispal
01:20 PM - 01:40 PM
27
Teratoma-derived myogenic progenitors for human skeletal muscle graftsMichael Kyba
01:40 PM - 03:00 PM
Lunch and Informal Discussion
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Dinner and Informal Discussions (Buses Depart from Hotel Lobby)
Saturday, October 04
08:00 AM - 08:30 AM
Breakfast
Chairs: Andreea Cojocaru and Foteini Mourkioti
08:30 AM - 08:50 AM
28
Human-specific regulatory mechanism revealed in a 3D embryo modelRaquel Fueyo, Sicong Wang, Olivia J. Crocker, Tomek Swigut, Hiromitsu Nakauchi, and Joanna Wysocka
08:50 AM - 09:10 AM
29
Stem cell-derived isogenic cortical organoids uncover mutation-specific vulnerability and neuroprotection in Alzheimer’s diseaseNatalia Rodriguez-Muela1, Tobias Grass1, and Caghan Kizil4
09:10 AM - 09:30 AM
30
Dietary Control of Stem Cells in Physiology and DiseaseOmer Yilmaz
09:30 AM - 09:45 AM
31
Distinct regenerative properties of Extra-ocular muscle mesenchymal stromal cells support muscle stem cell maintenanceValentina Taglietti1, Andreea Cojocaru1, Laurent Tiret2, Daniel Helzer3, Rachelle Crosbie3, Benedicte Chazaud4, Antonio Moretta4, and Frederic Relaix1
09:45 AM - 10:05 AM
32
Why do human haematopoietic stem cells lose function ex vivo? Elisa Laurenti
10:05 AM - 10:25 AM
33
Generating Bespoke Chimeric Brains From the BlastocystKristin Baldwin
10:25 AM - 10:45 AM
34
Mechanisms regulating stem cell plasticity during tumor initiationCédric Blanpain
10:45 AM - 11:30 AM
Coffee Break and Poster Viewing (Odd Numbers)
Chairs: John Nguyen and Omer Yilmaz
11:30 AM - 11:50 AM
35
Hoxa11/Hoxd11 Function is Required for Hh Signaling Response in Skeletal Stem CellsDeneen Wellik
11:50 AM - 12:10 PM
36
PAX3 drives muscle stem cell functional heterogeneity during muscle repairFred Relaix
12:10 PM - 12:25 PM
37
Building better blastoids: Generating high-fidelity human embryo modelsAmanda J Collier1, Peter Chovanec2, Shouzheng Yue3,4, Abigail S Krall1, Franziska Heinkele1, Jihui Sha1, Immy Ashley5,6, Ruby A Sims3,4, Liudmilla Rubbi7, Benjamin Feng1, Youngsun Hwang7, Amander T Clark7, Matteo Pellegrini7, Heather R Christofk1, Mehdi Bouhaddou5,6, Yi Yin2, James A Wohlschlegel1, Steven J Jonas3,4, and Kathrin Plath1
12:25 PM - 12:45 PM
38
NON-canonical roles of the Keap1/Nrf2 axis in regulating quiescence and early activation in adult muscle stem cells Zhenguo Wu
12:45 PM - 01:05 PM
39
Uncovering Cellular Crosstalk in the Pancreatic Islet Using Multicellular OrganoidsMaike Sander
01:05 PM - 01:20 PM
40
Synchronized Oscillation of the Common Core Gene Network Regulated by the BMP-ID2 Axis Determines Cyclic Regeneration and Resting Phases in Hair Follicle Stem Cells.Lukasz Boryn1, Patrycja Daszczuk1, Xiaoyang Wang2, Konrad Lukaszyk1, Ajay Jakhar1, Paula Mazurek1, Alicja Olczak1, Tomasz Pieczonka1, Guangfang Wang2, Raul Ramos2, Xiaojie Wang2, Agnieszka Kobielak1, Maksim Plikus2, Mark Israel3, Yun Kyuson4, and Krzysztof Kobielak1
01:20 PM - 01:40 PM
41
Stem cell aging: Evolutionary trade-offs and survivorship biasThomas Rando
01:40 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Archaeological Tour of Knossos and the Museum (Buses Depart Hotel Lobby)
08:00 PM - 11:00 PM
Dinner and Informal Discussions (Buses do not return to the hotel prior to dinner)
Sunday, October 05
08:00 AM - 08:30 AM
Breakfast
Chairs: Anna Pulawska-Czub and Hanna Mikkola
08:30 AM - 08:50 AM
42
Renewal and plasticity in gastrointestinal epitheliaOphir Klein
08:50 AM - 09:10 AM
43
Modulating cellular plasticity to promote tissue repair in intestinal diseaseHelen E Abud1,2,3, Diana Micati1,2, Shanika Amarasinghe1,2, Khan Ha Do1,2, Andrew Pattison1,2, Stuart Archer1,2, Lucy Porter1,2, Paul J McMurrick3, Edward Giles4,5, and Thierry Jarde1,2,3
09:10 AM - 09:30 AM
44
Live Imaging of Alveolar Stem Cells and their Fibroblast NicheNan Tang
09:30 AM - 09:45 AM
45
Epithelial-mesenchymal cell competition coordinates fate transitions across tissue
compartments during lung development and fibrosis.Kylie Klinkhammer, Rachel Warren, Joseph Knopp, Toan Nguyen, and Stijn De Langhe
09:45 AM - 10:05 AM
46
HERVHLin modulates pluripotency and protects the genome from mutagenic retroelements by rewiring the conserved LIN28A/let-7 pathway in the early human embryoZsuzsanna Izsvak1, Aleksandra M Kondrashkina1, Manvendra Singh1, Egor Semenchenko1, Amit Pande1, Jose l Garcia-Perez2, and Laurence D Hurst3
10:05 AM - 10:25 AM
47
Epigenetic control of fate decisions in muscle regenerationJeff Dilworth
10:25 AM - 10:45 AM
48
Stromal regulation of tissue repairValerie Horsley
10:45 AM - 11:25 AM
Coffee Break and Poster Viewing (Even Numbers)
Chairs: Candaice Newell and Valentina Lo Sardo
11:25 AM - 11:45 AM
49
Expanding Stem Cell-Based Cell and Gene Therapy Combinations for Treating Degenerative Diseases and BeyondAndras Nagy
11:45 AM - 12:05 PM
50
Live Tracing Reveals Regenerative Plasticity and Dysfunction in the Corneal NicheRuby Shalom-Feuerstein
12:05 PM - 12:25 PM
51
Refining astrocyte-to-neuron reprogramming specificity via microRNA-guided neuronal detargetingHussein Ghazale1,2, Martin Parga Pazos3, Sascha Jung3, Ke Cao1, Lakshmy Vasan1, Jack W Hickmott7, Linghe Zhang1, Cindi M Morshead7, Chao Wang1, Antonio del Sol9, and Carol Schuurmans1,2
12:25 PM - 12:40 PM
52
Polyamine metabolism regulates muscle stem cell and fibro-adipogenic progenitor proliferation and differentiation during skeletal muscle regenerationJohn H Nguyen1, Kristy Swiderski1, Kristin K Brown2, Robert N Judson4, Amy J Bongetti1, Jin D Chung5, Jennifer Trieu1, Annabel Chee1, Paul Gregorevic1, David P De Souza6, René Koopman1, Craig A Goodman1, and Gordon S Lynch1
12:40 PM - 01:00 PM
53
A machine learning-based computational platform for cellular conversion to generate functionally mature cells - an application on corticospinal neuronsAntonio del Sol
01:00 PM - 01:20 PM
54
Epigenetic regulation of epithelial cell plasticity in tissue regeneration and immunitySemir Beyaz
01:20 PM - 01:30 PM
Closing Remarks - Jeffrey Dilworth
01:30 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Farewell Dinner
Monday, October 06
08:00 AM - 10:00 AM
Breakfast
10:00 AM - 12:00 PM
Departure
