3rd International Conference on Oral Mucosal Immunity and Microbiome


Important: The program online is copyrighted to each author and should not be copied and pasted!
  • Aegean Conferences Communication  

    Please note that our registration fees include hotel accommodations and therefore no additional reservations are required. The only communication you should receive is from Aegean Conferences and if your paying by credit card, payment receipts from Conferex LLC. SCAM Alert: Beware of any third party companies calling and/or emailing you to reserve hotel accommodations for you during our conferences

    In completing the online registration form you are not automatically accepted to attend the conference nor are you automatically registered for the conference. Final registration to the conference shall occur after you have been accepted and notified by the conference chair of your acceptance to the conference. If you have been charged the registration fee but your attendance has been declined you will be reimbursed in full.

    Please note that Crete has two airports. You want to arrive at the Heraklion International Airport (code: HER) and take a taxi from the airport to the hotel (~60 EUR). You may also rent a car at the airport and drive to the conference center. Alternatively Chania International Airport (CHQ) is a two-hour drive to the Conference Center.

    Accommodation Tax
    An accommodation tax of € 4.00 per room night will apply, and will be charged automatically to the individual guest’s extras accounts. 

    Accommodations for the conference are at the Aldemar Hotel.  The hotel is located in Hersonissos, 27 km from Heraklion International Airport.  Please take a taxi from the airport to the conference venue. 

    Arrival and Check-in 
    It is expected that attendees will arrive/check-in after 3:00 PM. Anyone arriving after 10:30 pm on the first day should make alternative dinner arrangements.

    Conference Venue
    The Aldemar Conference Center is located at the hotel. 

    Handicapped Accessibility
    The site is fully handicapped accessible.

    Oral Presentations
    Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session.  The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A.

    Archaeological Site of Knossos and City Tour
    Buses for the city tour will depart from the hotel front lobby at 3:30 pm. Badges are required for participation. 

    Breakfast for registered participants and registered accompanying persons will be served at the Aldemar Knossos Royal Village main restaurant during the hours scheduled in this program. 

    Lunches/Informal Discussions
    Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant and only after the session has finished. Badges are required for admission.

    Dinners/Informal Discussions
    Three of the dinners/informal discussion will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting.  Please contact info@aegeanconferences.org. 

    Internet, Phone, & Computer 
    Wireless Internet access is located throughout the conference center free of charge during meeting hours. There are computers available in the hotel’s business center for the use of the attendees. Phone service is available for an additional charge from your hotel room.

    Certificate of Participation
    A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session. 

    Passports and Visa
    Participants are advised to check on their individual requirements before attending any Aegean Conference meeting. Visa applications should be filed at the nearest Greek Embassy in the country in which you are resident, at least three months prior to the anticipated departure date.

    Letters of Invitation
    Letters of invitation to attend an Aegean Conference meeting will be issued only to:

    • Authors of accepted abstracts
    • Fully paid registrants

    Note: Invitations are issued at the discretion of Aegean Conferences, and requests for letters will be accepted only 60 days prior to the conference start date.

    Liability and Insurance
    Neither the organizers, nor the Aegean Conferences will assume any responsibility whatsoever for damage or injury to persons or property during meeting period. Participants are advised to arrange their own personal travel and health insurance.  

    Other Information
    Animals are not permitted on site.
    Badges are required for admission to all events.
    All Aegean Conferences events are non-smoking. 

    No Photographs and Recording Devices 
    Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations. 

    Code of Conduct Policy 
    Aegean Conferences is committed to making its meetings an inclusive space for sharing ideas and knowledge. The code of conduct can be viewed here. 


Tuesday, September 26

06:30 PM - 07:30 PM
Conference Registration
07:30 PM - 10:30 PM
Welcome Reception Drink and Dinner "Taverna Artemis"

Wednesday, September 27

07:30 AM - 08:15 AM
08:15 AM - 08:30 AM
Welcome and Opening Remarks - George Belibasakis
Microbial Pathogenesis I
Chairs: Jan Potempa and Silvia Uriarte
08:30 AM - 08:50 AM
Tyrosine Kinase Ptk1 Couples One Carbon Metabolism and Virulence in P. gingivalis
Richard J Lamont
08:50 AM - 09:10 AM
Manipulating Efferocytosis: A New Role for P. gingivalis Proteases
Kelley N Cooper2, Jan Potempa2, and Juhi Bagaitkar1,3
09:10 AM - 09:30 AM
Persistence of Tannerella forsythia and Fusobacterium nucleatum in the Dental Plaque: Dependence on Metabolic Give and Take
Ashu Sharma
09:30 AM - 09:50 AM
Dissecting how sialic acid shapes the life of <i>Tannerella forsythia<i/>, and beyond
Graham P Stafford
09:50 AM - 10:10 AM
Does the red-complex bacterium Tannerella forsythia induce a specific host response?
Oleh Andrukhov1 and Christina Schäffer2
10:10 AM - 10:30 AM
Fusobacterial mediated tumor immune-evasion
Amjad Shhadeh1, Nicole Haj1, Tamar Alon-Maimon1, Ofir Ventura1, Reem Bsoul1, Perlie Admony1, Viviana Scaiewicz1, Ofer Mandelboim2, and Gilad Bachrach1
10:30 AM - 11:20 AM
Coffee Break and Poster Viewing
Host Response and Inflammation I
Chairs: Dana Graves and Shauna Culshaw
11:20 AM - 11:40 AM
Animal models in oral science and their relevance to understand human disease
George Hajishengallis
11:40 AM - 12:00 PM
The expanding landscape of complement pathobiology and therapeutic opportunity
Dimitrios C. Mastellos1, George Hajishengallis3, and John D. Lambris2
12:00 PM - 12:20 PM
Interplay of host factors and bacterial infection in a mouse model of oral lichen planus
Youngnim Choi
12:20 PM - 12:40 PM
The pivotal role of MAIT cells in periodontitis associated with LAD1
Tetsuhiro Kajikawa1, Patricia Diaz5, Triantafyllos Chavakis4, Niki M. Moutsopoulos3, and George Hajishengallis2
12:40 PM - 01:00 PM
Role of osteoclast precursors in periodontal bone loss
Ping Zhang
01:00 PM - 01:20 PM
Bone biology in implant dentistry and beyond
Reinhard Gruber
01:20 PM - 01:35 PM
Calprotectin affects neutrophil and inflammatory CD4 T cell infiltrates in ligature-induced periodontitis
Peter D. Bittner-Eddy, Lori A. Fischer, Karen F. Johnstone, Mark C. Herzberg, and Massimo Costalonga
01:35 PM - 01:50 PM
Langerhans cells shape postnatal oral homeostasis in a mechanical force-dependent but microbiota and IL17-independent manner
Yasmin Jaber and Avi-Hai Hovav
01:50 PM - 03:20 PM
Lunch and Informal Discussions
03:20 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Dinner and Informal Discussions - Buses Depart Hotel Lobby

Thursday, September 28

07:30 AM - 08:30 AM
Microbial Pathogenesis II
Chairs: Richard Lamont and Hui Wu
08:30 AM - 08:50 AM
Functional and structural insights into the regulation of gingipain secretion and maturation by PorX response regulator
Jan Potempa1,2, Zuzanna Nowakowska1, Mariusz Madej1, Kendall Stocke2, Richard Lamont2, and Malgorzata Benedyk-Machaczka1
08:50 AM - 09:10 AM
Single cell heterogeneity in oral pathogens: Unveiling the Microbial Mosaic
Marvin Whiteley
09:10 AM - 09:30 AM
P. gingivalis infection upregulates PD-L1 expression on dendritic cells, suppresses CD8+ T-cell responses, and aggravates oral cancer
Junling Ren1, Xiao Han1, Hannah Lohner1, Shuang Liang3, Jiong Li2, and Huizhi Wang1
09:30 AM - 09:50 AM
It takes two to tango: The contribution of Filifactor alocis and TLR2 to foster a dysbiotic relationship with the host causing alveolar bone loss.
Silvia M. Uriarte
09:50 AM - 10:10 AM
Effect of Phospholipase A2-IIA in Oral Dysbiosis and Periodontal Disease
Vanessa Tubero Euzebio Alves1, Robert Danaher1, Sreenatha Kirakodu1, Danielle Bellamy1, Roger M Arce3, Jorge Frias Lopez2, and Octavio A Gonzalez Duque1
10:10 AM - 10:30 AM
Parvimonas micra hiding in plain sight: new insights into an uncharacterized pathobiont
Justin L Merritt
10:30 AM - 11:20 AM
Coffee Break and Poster Viewing
Oral and Systemic Diseases
Chairs: Juhi Bagaitkar and Ashu Sharma
11:20 AM - 11:40 AM
An scRNA-seq Analysis of the Impact of Diabetes on the Host Response in Periodontitis
Bushra Alghamdi1, Min Liu1, Michael Troka1, Kang Ko1, Michael Gonzalez2, and Dana T Graves1
11:40 AM - 12:00 PM
Mouth-Gut Connection: A alternative causal mechanism for the link between periodontal disease and systemic diseases
Kazuhisa Yamazaki
12:00 PM - 12:20 PM
The Influence of Periodontitis on the Oral-Gut Microbiome Axis
Armond June, Lu Li, and Patricia I Diaz
12:20 PM - 12:40 PM
Maladaptive innate immune training of myelopoiesis links periodontitis and arthritis
Xiaofei Li1, Hui Wang2, Triantafyllos Chavakis3, and George Hajishengallis2
12:40 PM - 01:00 PM
Aberrant immunity in periodontitis - local and systemic consequences
Shauna Culshaw
01:00 PM - 01:20 PM
Bond between oral microbiome and pregnancy outcomes
Nagihan Bostanci
01:20 PM - 01:40 PM
Endotoxemia - cause and consequence.
Pirkko Pussinen
01:40 PM - 01:55 PM
Impact of periodontitis on stroke severity : an experimental study
Marjolaine Gosset1, Banndith Cheat1, Gabrielle Mangin2, Giuseppina Giuseppina2, Jerome Bouchet1, and Sandrine Delbosc2
01:55 PM - 03:20 PM
Lunch and Informal Discussions
03:20 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Dinner and Informal Discussions - Buses Depart Hotel Lobby

Friday, September 29

07:30 AM - 08:30 AM
Microbial Pathogenesis III
Chairs: Hyun Michel Koo and Jens Kreth
08:30 AM - 08:50 AM
IFN-g/STAT1-mediated immunopathology drives epithelial barrier disruption and oral mucosal candidiasis
Michail Lionakis
08:50 AM - 09:10 AM
Oral Candida albicans infection is driven by the peptide toxin candidalysin
Julian Naglik
09:10 AM - 09:30 AM
Modulation of Candida Virulence by Oral Bacteria
Anna Dongari, Roberto Vazquez Munoz, Takanori Sobue, and Angela Thompson
09:30 AM - 09:50 AM
“Oral fungi, conductors of health and disease”
Bastiaan Philip Krom
09:50 AM - 10:05 AM
Impact of arginine on autolysis of Porphyromonas gingivalis
Mary Ellen Davey
10:05 AM - 10:20 AM
Tannerella species in periodontal health versus disease
Christina R. Schäffer1, Fiona F. Hager-Mair1, fabian L. Kendlbacher1, Stephanie Walcher1, Susanne Bloch2, and Oleh Andrukhov2
10:20 AM - 10:35 AM
Quorum quenching enzyme Aii20J fosters the homeostatic species Streptococcus cristatus in cariogenic biofilms
Ana Parga1, Sabela Balboa2, Paz Otero-Casal3,4, and Ana Otero2
10:35 AM - 11:20 AM
Coffee Break and Poster Viewing
Polymicrobial Communities
Chairs: Patricia Diaz and Sinem Esra Sahingur
11:20 AM - 11:40 AM
Spatial structure of polymicrobial communities modulates biofilm virulence in situ
Hyun (Michel) Koo
11:40 AM - 12:00 PM
Determinants of human oral microbial biogeography
Jens Kreth
12:00 PM - 12:20 PM
Polymicrobial cooperation and competition
Hui Wu
12:20 PM - 12:40 PM
microbial food chain: nutritional interactions promoting periodontitis
Masae Kuboniwa
12:40 PM - 01:00 PM
Overcoming environmental stress: survival skills
Hansel M Fletcher
01:00 PM - 01:15 PM
Interkingdom assemblages in human saliva display group-level surface mobility and disease-promoting emergent functions
Zhi Ren1, Hannah Jeckel2, Aurea Simon-Soro1, Zhenting Xiang1, Yuan Liu1, Indira M. Cavalcanti1, Xiao Jin3, Nyi-Nyi Tin4, Anderson Hara4, Knut Drescher2, and Hyun Koo1
01:15 PM - 01:30 PM
Microbial dysbiosis during experimental periodontitis
Marion Arce1,2,3, Natalia Endo2, Nicolás Dutzan1,2,3, and Loreto Abusleme1,2,3,4
01:30 PM - 01:45 PM
Manipulation of the host immune response by Porphyromonas gingivalis: The role of PPAD-modified accessory fimbriae subunits in TLR2-dependent signaling in phagocytes
Aleksandra Wielento1, Juhi Bagaitkar2, Aleksander M Grabiec1, and Jan Potempa1,3
01:45 PM - 03:15 PM
Lunch and Informal Discussions
03:30 PM - 07:30 PM
City Tour (Buses Depart Hotel Lobby)
07:30 PM - 11:00 PM
Dinner and Informal Discussions (Buses do not return to hotel prior to dinner)

Saturday, September 30

07:30 AM - 08:30 AM
Host Response and Inflammation II
Chairs: Julie Teresa Marchesan and Julian Naglik
08:30 AM - 08:50 AM
Trained innate immunity and its impact on health and disease
Triantafyllos Chavakis
08:50 AM - 09:10 AM
Metabolic Reprogramming of Myeloid-derived Suppressor Cells in Periodontal Disease
Keith L Kirkwood
09:10 AM - 09:30 AM
Matriline Impact on Gingival Transcriptome and Microbiome in Periodontitis Resistant and Susceptible Nonhuman Primates
Jeffrey Ebersole1, Sreenatha Kirakodu2, Linh M Nguyen1, and Octavio A Gonzalez2
09:30 AM - 09:50 AM
Elucidation of Oral Aging Mechanisms and Development of Aging-Related Oral Disease Treatments Focusing on the DEL-1
Tomoki Maekawa1, Kridtapat Sirisereephap1, and George Hajishengallis2
09:50 AM - 10:05 AM
Chronic graft-versus-host disease patient mucosa contains two expanded populations of dysregulated exhausted-like effector tissue resident CD8+ T-cells unveiled by spatial transcriptomics and scRNA seq
Ana C. Costa da Silva1, Rubina Sharma1, Daniel Martin1, Steven Z. Pavletic2, and Jacqueline W. Mays1
10:05 AM - 10:20 AM
Sex-specific regulation of IL-1b-mediated bone loss in periodontitis
Tomaz Alves da Silva Neto1, Karen V. Swanson2, Mustafa S. Girnary1, Marcelo Freire4, Pollyana Coelho Pessoa Santos1, Kevin Moss1, James Beck1, Kimon Divaris5, Willie June Brickey6, John A. Wrobel7, William T. Seaman8, John S. Preisser9, Di Hu9, Dilek Uyan1, Thiago Morelli1, Cristiano Susin1, Nishma P. Vias1, Maya S. Styner10, Shaoping Zhang11, Lufei Wang1, Adam D. Lietzan1, Marla Oneal1, Koby T. Martin1, Zoha Durrani1, Jennifer Webster-Cyriaque8, Jenny P. Y. Ting7, and Julie T. Marchesan1
10:20 AM - 11:20 AM
Coffee Break and Poster Viewing
Oral Disease Mechanisms and Treatment
Chairs: Keith Kirkwood and Jeffrey Ebersole
11:20 AM - 11:40 AM
Uncovering the connection between cellular senescence and periodontal health
Esra Sahingur
11:40 AM - 12:00 PM
Targeting precise pathways for periodontal care
Julie T Marchesan
12:00 PM - 12:20 PM
Disruption of the Microbiome-Biomaterial-Tissue equilibrium in peri-implant disease
Georgios A Kotsakis
12:20 PM - 12:40 PM
Bone remodeling-related biomarkers following periodontal transplantation of the tissue engineered biocomplex
Danae A Apatzidou1, Antonis Konstantinidis1, David F Lappin2, and Christopher Nile3
12:40 PM - 01:00 PM
Oral microbiome and immune mechanisms in periodontal and systemic disease link
Hatice Hasturk
01:00 PM - 01:15 PM
impact of pre-transplant periodontal disease on the microbiology of bacterial bloodstream infections in Allo-HSCT patients
Omnia Elebyary1,2, Junhyung John Lee2, Mohamad Dukuray2, Erin Watson2, Bryan Coburn3, and Michael Glogauer1,2
01:15 PM - 01:30 PM
Augmented Local and Systemic Immune Responses against Citrullinated Peptides from Both Host and P. gingivalis Support a Mucosal Origin of Autoimmunity in Rheumatoid Arthritis
Daniel Manoil1, Anne-Marie Quirke3, Gonca Mumcu4, Nevsun Inanc5, Meryem Can6, Haner Direskeneli5, and Nagihan Bostanci2
01:30 PM - 01:35 PM
01:35 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Farewell Dinner

Sunday, October 01

08:00 AM - 10:00 AM
10:00 AM - 12:00 PM