18th International Conference on Innate Immunity

Program

Important: The program online is copyrighted to each author and should not be copied and pasted!
  • Aegean Conferences Communication  

    Please note that our registration fees include hotel accommodations and therefore no additional reservations are required. The only communication you should receive is from Aegean Conferences and if your paying by credit card, payment receipts from Conferex LLC. SCAM Alert: Beware of any third party companies calling and/or emailing you to reserve hotel accommodations for you during our conferences

    Registration 

    In completing the online registration form you are not automatically accepted to attend the conference nor are you automatically registered for the conference. Final registration to the conference shall occur after you have been accepted and notified by the conference chair of your acceptance to the conference. If you have been charged the registration fee but your attendance has been declined you will be reimbursed in full.

    Airport

    Please note that Crete has two airports. You want to arrive at the Chania International Airport (code: CHQ) and take a taxi from the airport to the hotel (~60 EUR). You may also rent a car at the airport and drive to the conference center. Alternatively the other airport (HER) is a two-hour drive to the Conference Center.

    Accommodation Tax

    An accommodation tax of € 4.00 per room night will apply, and will be charged automatically to the individual guest’s extras accounts. 

    Accommodations

    Accommodations for the conference are at the Avra Imperial Hotel.  The hotel is located in Kolymbari, 39 km from Chania International Airport, 23 km from the Souda Harbor, and 23 km west of Chania town center.  Please take a taxi from the airport to the conference venue. 

    Arrival and Check-in

    It is expected that attendees will arrive/check-in after 3:00 PM. Anyone arriving after 10:30 pm on the first day should make alternative dinner arrangements.

    Conference Venue

    The Avra Imperial Conference Center is located at the hotel. 

    Handicapped Accessibility

    The site is fully handicapped accessible.

    Oral Presentations

    Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session.  The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A.

    City Tour

    Buses for the city tour will depart from the hotel front lobby at 3:30 pm. Badges are required for participation. 

    Breakfast

    Breakfast for registered participants and registered accompanying persons will be served at the Avra Imperial Hotel main restaurant during the hours scheduled in this program. 

    Lunches/Informal Discussions

    Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant and only after the session has finished. Badges are required for admission.

    Dinners/Informal Discussions

    Three of the dinners/informal discussion will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting.  Please contact info@aegeanconferences.org. 

    Internet, Phone, & Computer

    Wireless Internet access is located throughout the conference center free of charge during meeting hours. There are computers available in the hotel’s business center for the use of the attendees. Phone service is available for an additional charge from your hotel room.

    Certificate of Participation

    A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session. 

    Passports and Visa
    Participants are advised to check on their individual requirements before attending any Aegean Conference meeting. Visa applications should be filed at the nearest Greek Embassy in the country in which you are resident, at least three months prior to the anticipated departure date.

    Letters of Invitation
    Letters of invitation to attend an Aegean Conference meeting will be issued only to:

    • Authors of accepted abstracts
    • Fully paid registrants

    Note: Invitations are issued at the discretion of Aegean Conferences, and requests for letters will be accepted only 60 days prior to the conference start date.

    Liability and Insurance
    Neither the organizers, nor the Aegean Conferences will assume any responsibility whatsoever for damage or injury to persons or property during meeting period. Participants are advised to arrange their own personal travel and health insurance.  

    Other Information

    Animals are not permitted on site.

    Badges are required for admission to all events.

    All Aegean Conferences events are non-smoking.

    No Photographs and Recording Devices

    Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations. 

    Code of Conduct Policy 

    Aegean Conferences is committed to making its meetings an inclusive space for sharing ideas and knowledge. The code of conduct can be viewed here. 

Wednesday, May 31

06:30 PM - 07:30 PM
Conference Registration
07:30 PM - 10:30 PM
Welcome Reception & Dinner

Thursday, June 01

07:30 AM - 08:20 AM
Breakfast
08:20 AM - 08:30 AM
Welcome & Opening Remarks
TLR/NLR signaling
Chairs: Igor Brodsky and Georgios Hajishengallis
08:30 AM - 08:55 AM
Inflammasome activation by bacterial toxins
Si Ming Man
08:55 AM - 09:20 AM
Cellular redox state controls gasdermin D pore formation and pyroptosis
Charles Evavold
09:20 AM - 09:45 AM
Lipid regulation of inflammasome activation
Clare Bryant
09:45 AM - 10:10 AM
Targeting innate immunity and inflammatory cell death, PANoptosis, for the treatment of inflammatory and infectious diseases
Thirumala-Devi Kanneganti
10:10 AM - 10:35 AM
TBA - Linkermann
Andreas linkermann
10:35 AM - 10:50 AM
An SP110 / SP100 regulatory axis that controls innate immunity stimulation
Eric Aird and Jacob Corn
10:50 AM - 11:45 AM
Coffee Break and Poster Viewing
Macrophage activation
Chairs: Renato Ostuni and Gabrielle Belz
11:45 AM - 12:10 PM
Macrophages in drug discovery
Christina Arnold
12:10 PM - 12:35 PM
Where does the bigger version of macrophages - giant cells - come from?
Gernot Schabbauer
12:35 PM - 01:00 PM
Mechanical regulation of inflammation in fibrotic niches
Kyle Vining
01:00 PM - 01:25 PM
Senescent cells suppress macrophage-mediated corpse removal via upregulation of the CD47-QPCT/L axis
Karim El Kasmi
01:25 PM - 01:50 PM
Response of resident peritoneal macrophages to infection and tumor metastasis
Carlos Ardavin
01:50 PM - 02:05 PM
Versatile ways to obtain versatile cells: proteomics-based understanding of macrophage priming by environmental signals
Natasja Otto1, Hanke Matlung2, Eva Smit1, Arie Hoogendijk1, and Maartje Van den Biggelaar1
02:05 PM - 03:30 PM
Lunch and Informal Discussions
03:30 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Dinner and Informal Discussions

Friday, June 02

07:30 AM - 08:30 AM
Breakfast
Granulocyte Biology
Chairs: Charlie Evavold and Clare Bryant
08:30 AM - 08:55 AM
Transcriptional control of myeloid cell identity and activation
Renato Ostuni
08:55 AM - 09:20 AM
Hypoxia induced epigenetic changes are associated with long lasting perturbations in neutrophil metabolic and functional programs in health and disease.
Sarah Walmsley
09:20 AM - 09:45 AM
The assembly and activation of the NLRP3 inflammasome require the Rab11-family interacting protein 2
Terje Espevik, Harald Husebye, Caroline Gravastrand, and Mariia Yurchenko
09:45 AM - 10:10 AM
The dawn of clinical C3 inhibition: the story, its milestones and what lies ahead
John D. Lambris
10:10 AM - 10:35 AM
Regulation of noncanonical inflammasome assembly
Igor Brodsky
10:35 AM - 10:50 AM
Oxidised cholesterols drive macrophage infiltration into the lung during bacterial and viral respiratory infections
Cheng Foo, Stacey Bartlett, Minh Ngo, Christian Smith, and Katharina Ronacher
10:50 AM - 11:45 AM
Coffee Break and Poster Viewing
Immune Function
Chairs: Carlos Ardavin and Thirumala-Devi Kanneganti
11:45 AM - 12:10 PM
Self-renewing tissue-resident innate cell programs regulate local lung responses
Gabrielle Belz
12:10 PM - 12:35 PM
Impact of the tumor microenvironment on the NK cell function: the effect of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSC) and mechanism of PD-1 expression
Lorenzo Moretta, Nicola Tumino, Paola Vacca, Francesca Romana Mariotti, and Linda Quatrini
12:35 PM - 01:00 PM
Type I Interferon Exhaustion
Elina Zuniga
01:00 PM - 01:25 PM
Innate versus adaptive TCR engagement in gamma delta T cell activation
Leticia Monin1, Florencia Cano1, Daisy Melandri1, and Adrian Hayday1
01:25 PM - 01:50 PM
Perivascular Macrophages in the intersection of health and disease
Hernandez Moura Silva
01:50 PM - 02:05 PM
Deciphering the role of long non-coding RNAs in the immunosuppression of natural killer cells.
Andrea Pelosi1, Silvia Santopolo1, Claudia Alicata1, Francesca Mariotti1, Nicola Tumino2, Paola Vacca2, and Lorenzo Moretta1
02:05 PM - 03:30 PM
Lunch and Informal Discussion
03:30 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Dinner and Informal Discussions

Saturday, June 03

07:30 AM - 08:30 AM
Breakfast
Immunometabolism
Chairs: Si Ming Man and Christina Stallings
08:30 AM - 08:55 AM
Inhibition of MPC simultaneously mitigates hyperinflammation and hyperglycemia in COVID-19
Jie Sun
08:55 AM - 09:20 AM
Why do we survive or die from infections?
Miguel Soares
09:20 AM - 09:45 AM
Systematic discovery of druggable redox switches on immunological proteins
Ed Chouchani
09:45 AM - 10:10 AM
Immunological control of ferroptosis by tryptophan metabolism
Peter Murray
10:10 AM - 10:35 AM
Deep phenotyping and immuno-monitoring of human cohorts and myeloid cells in cancer
Subhra Biswas
10:35 AM - 10:50 AM
The histone demethylase KDM3A modulates macrophage pro-inflammatory phenotype in atherosclerosis
Ricky Siebeler, Marten Hoeksema, Hung-Jen Chen, and Menno de Winther
10:50 AM - 11:45 AM
Coffee Break and Poster Viewing
Innate Immune Training and Modulation
Chairs: Gernot Schabbauer and Elina Zuniga
11:45 AM - 12:10 PM
Novel insights in trained immunity
Mihai Netea
12:10 PM - 12:35 PM
TBA - Maziar Divangahi
Maziar Divangahi
12:35 PM - 01:00 PM
Clonal hematopoiesis and inflammatory disease
George Hajishengallis
01:00 PM - 01:25 PM
Immunometabolic circuits in inflammation and innate immunity
Triantafyllos Chavakis
01:25 PM - 01:50 PM
Your mind on allergies: a protective mast cell-brain circuit
Esther Florsheim
01:50 PM - 02:05 PM
High throughput screen for small molecule inducers of trained immunity
Hannah Knight1, Qing Chen1, Jingjing Shen1, Ka Man Ip2, and Aaron Esser-Kahn1
02:05 PM - 03:00 PM
Lunch and Informal Discussions
03:30 PM - 07:30 PM
City Tour
07:30 PM - 11:00 PM
Dinner and Informal Discussions

Sunday, June 04

07:30 AM - 08:30 AM
Breakfast
Large Data Analysis
Chairs: Triantafyllos Chavakis and Katrin Mayer-Barber
08:30 AM - 08:55 AM
TBA - Musa Mhlanga
Musa Mhlanga
08:55 AM - 09:20 AM
Innate Immunity and Cardiac Repair
Kory Lavine
09:20 AM - 09:45 AM
Unraveling Genetic and Epigenetic Regulations of Immune Response in Disease and Trained Immunity through Integration of Multi-omic and Single-Cell Data
Yang Li
09:45 AM - 10:10 AM
Emerging Immune Regulatory Roles of GARP in Cancer: Beyond Tregs
Maria Velegraki and Zihai Li
10:10 AM - 10:35 AM
Cellular and Humoral Innate Immunity from Cancer to Covid-19
Alberto Mantovani
10:35 AM - 10:50 AM
Protein turnover profiling in Influenza A virus-infected cells identifies a novel class of virus-affected proteins
Yiqi Huang1, Christian Urban1, Philipp Hubel1,2, Alexey Stukalov1, and Andreas Pichlmair1
10:50 AM - 11:45 AM
Coffee Break and Poster Viewing
Infection-Immune Interface
Chairs: Hernandez Moura Souza and Sarah Walmsely
11:45 AM - 12:10 PM
Dissecting the complexity of myeloid cells in TB granulomas
Bryan Bryson
12:10 PM - 12:35 PM
TBA - Shabaana Khader
Shabaana Khader
12:35 PM - 01:00 PM
Inflammation as a Driver of Mycobacterium tuberculosis pathogenesis
Christina Stallings
01:00 PM - 01:25 PM
Cellular and molecular mechanisms of innate inflammation in response to MTb and SARS-CoV2
Katrin Meyer-Barber
01:25 PM - 01:40 PM
Training human hematopoietic stem cells: a novel vaccination strategy against Tuberculosis
Eva Kaufmann1,2, Renata Monteiro Sindeaux2, Peipei Zeng2, Sara Teimouri Nezhad2, Nargis Khan2,5, Clinton Robbins3, Philippe Joubert4, Jun Ding2, and Maziar Divangahi2
01:40 PM - 01:55 PM
Closing Remarks
01:55 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Farewell Dinner

Monday, June 05

07:30 AM - 10:00 AM
Breakfast
10:00 AM - 12:00 PM
Departure