5th International Conference on ImmunoMetabolism: Molecular and Cellular Immunology of Metabolism


Important: The program online is copyrighted to each author and should not be copied and pasted!
  • Aegean Conferences Communication  

    Please note that our registration fees include hotel accommodations and therefore no additional reservations are required. The only communication you should receive is from Aegean Conferences and if your paying by credit card, payment receipts from Conferex LLC. SCAM Alert: Beware of any third party companies calling and/or emailing you to reserve hotel accommodations for you during our conferences


    In completing the online registration form you are not automatically accepted to attend the conference nor are you automatically registered for the conference. Final registration to the conference shall occur after you have been accepted and notified by the conference chair of your acceptance to the conference. If you have been charged the registration fee but your attendance has been declined you will be reimbursed in full.


    Please note that Crete has two airports. You want to arrive at the Chania International Airport (code: CHQ) and take a taxi from the airport to the hotel (~60 EUR). You may also rent a car at the airport and drive to the conference center. Alternatively the other airport (HER) is a two-hour drive to the Conference Center.

    Accommodation Tax

    An accommodation tax of € 4.00 per room night will apply, and will be charged automatically to the individual guest’s extras accounts. 


    Accommodations for the conference are at the Avra Imperial Hotel.  The hotel is located in Kolymbari, 39 km from Chania International Airport, 23 km from the Souda Harbor, and 23 km west of Chania town center.  Please take a taxi from the airport to the conference venue. 

    Arrival and Check-in

    It is expected that attendees will arrive/check-in after 3:00 PM. Anyone arriving after 10:30 pm on the first day should make alternative dinner arrangements.

    Conference Venue

    The Avra Imperial Conference Center is located at the hotel. 

    Handicapped Accessibility

    The site is fully handicapped accessible.

    Oral Presentations

    Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session.  The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A.

    City Tour

    Buses for the city tour will depart from the hotel front lobby at 3:30 pm. Badges are required for participation. 


    Breakfast for registered participants and registered accompanying persons will be served at the Avra Imperial Hotel main restaurant during the hours scheduled in this program. 

    Lunches/Informal Discussions

    Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant and only after the session has finished. Badges are required for admission.

    Dinners/Informal Discussions

    Three of the dinners/informal discussion will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting.  Please contact info@aegeanconferences.org. 

    Internet, Phone, & Computer

    Wireless Internet access is located throughout the conference center free of charge during meeting hours. There are computers available in the hotel’s business center for the use of the attendees. Phone service is available for an additional charge from your hotel room.

    Certificate of Participation

    A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session. 

    Passports and Visa
    Participants are advised to check on their individual requirements before attending any Aegean Conference meeting. Visa applications should be filed at the nearest Greek Embassy in the country in which you are resident, at least three months prior to the anticipated departure date.

    Letters of Invitation
    Letters of invitation to attend an Aegean Conference meeting will be issued only to:

    • Authors of accepted abstracts
    • Fully paid registrants

    Note: Invitations are issued at the discretion of Aegean Conferences, and requests for letters will be accepted only 60 days prior to the conference start date.

    Liability and Insurance
    Neither the organizers, nor the Aegean Conferences will assume any responsibility whatsoever for damage or injury to persons or property during meeting period. Participants are advised to arrange their own personal travel and health insurance.  

    Other Information

    Animals are not permitted on site.

    Badges are required for admission to all events.

    All Aegean Conferences events are non-smoking.

    No Photographs and Recording Devices

    Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations. 

    Code of Conduct Policy 

    Aegean Conferences is committed to making its meetings an inclusive space for sharing ideas and knowledge. The code of conduct can be viewed here. 

Sunday, May 21

05:30 PM - 07:30 PM
Conference Registration
07:30 PM - 10:30 PM
Welcome Reception & Dinner

Monday, May 22

08:00 AM - 08:50 AM
08:50 AM - 09:00 AM
Welcome & Opening Remarks
Inflammation I
Chair: Allyson Evans
09:00 AM - 09:30 AM
Perchance to Dream: Sleep and Neuroinflammation
Douglas R. Green
09:30 AM - 10:00 AM
Mitochondrial DNA metabolism, inflammation, and autoimmunity
Michael Karin and Hongxu Xian
10:00 AM - 10:30 AM
Immunometabolic checkpoints of inflammaging
Vishwa Deep Dixit
10:30 AM - 10:45 AM
Macrophage fatty acid metabolism promotes splenic hematopoiesis through mitochondrial signaling during obesity and hypertension
Mallory Filipp1, Zhi-Dong Ge1,3, Connor Lantz1, Samuel Weinberg1, Sanjiv Shah2, and Edward Thorp1,3
10:45 AM - 11:00 AM
Skewed polyamine metabolism leads to functional defects in tissue-derived regulatory T cells during chronic inflammation in humans
Teresa Neuwirth Neuwirth1,2, Daniel Malzl2,5, Lisa Kleissl1,2,3, Anna Redl1,2, Davide Seruggia2,4, Jörg Menche2,5, and Georg Stary1,2,3
11:00 AM - 12:00 PM
Coffee Break and Poster Viewing
Gut, Liver
Chair: Triantafyllos Chavakis
12:00 PM - 12:30 PM
A Th17 cell-intrinsic ROS-scavenging-IL22 axis protects against intestinal inflammation
Dirk Brenner
12:30 PM - 01:00 PM
Adipose tissue remodeling in the presence of gut microbes
Suzanne Devkota
01:00 PM - 01:30 PM
A transient and spatially-restricted subset of resident Kupffer Cells induced by lipid uptake.
Anna Bujko, Federico F. De Ponti, Zhuangzhuang Liu, Paul Collins, Tinne Thoné, Liesbet Martens, Bavo Vanneste, and Charlotte L. Scott
01:30 PM - 02:00 PM
Pre-malignant disease-associated hepatocytes: a novel biomarker to stage chronic liver disease and predict future liver cancer risk.
Janina E.E. Tirnitz-Parker
02:00 PM - 02:15 PM
Diet, Microbiome and Immune System Trialogue in Liver Cancer Development and Response to Therapy
Nicolas Ryujin1, Mark Long3, Spencer Rosario3, Jian Huang1, Ashish Damania2,3, Nadim Ajami2, and Shabnam Shalapour1
02:15 PM - 03:30 PM
Lunch and Informal Discussions
03:30 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Dinner and Informal Discussions

Tuesday, May 23

08:00 AM - 09:00 AM
Inflammation II
Chair: Steve Shoelson
09:00 AM - 09:30 AM
Why is exercise anti-inflammatory? Role of extracellular vesicles in prevention of metabolic disease
Mark Febbraio
09:30 AM - 10:00 AM
Immune-mediated Lipid Cycle in Adipose Tissue
Anthony Ferrante, Xiaoyuan Xu, Joshua Goodman, and Kunheng Cai
10:00 AM - 10:30 AM
Immunometabolic circuits in inflammation and innate immunity
Triantafyllos Chavakis
10:30 AM - 10:45 AM
COMMD10 deficient adipose tissue macrophages protect from obesity and insulin resistance by boosting mitochondrial function and redox balance
Shani Ben Shlomo1, Ifat Abramovich2, Eyal Gottlieb2, Dayana Yahalomi3, Chen Varol1, and Nathan Gluck1
10:45 AM - 11:00 AM
Immunometabolic changes during experimental and clinical sepsis
Markus Huber-Lang, Ludmila Lupu, Marco Mannes, Lisa Wohlgemuth, and Rebecca Halbgebauer
11:00 AM - 12:00 PM
Coffee Break and Poster Viewing
T cells
Chair: Mark Febbraio
12:00 PM - 12:30 PM
Metabolic regulation of exhausted T cells in chronic infection and cancer
Axel Kallies
12:30 PM - 01:00 PM
Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment
Matteo Villa, David E. Sanin, and Erika L. Pearce
01:00 PM - 01:30 PM
Dysfunctional Mitochondria guide T cell exhaustion
Ping-Chih Ho
01:30 PM - 02:00 PM
Unravelling the role of adipose tissue resident T cells in tumor immune surveillance
Panos Verginis
02:00 PM - 03:30 PM
Lunch and Informal Discussions
03:30 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Dinner and Informal Discussions

Wednesday, May 24

08:00 AM - 09:00 AM
Cancer Immunometabolism II
Chair: Erika Pearce
09:00 AM - 09:30 AM
Metabolic Transitions in Cancer
Heather Christofk
09:30 AM - 10:00 AM
Dissecting the crosstalk of tumor mutations and inflammation in lung cancer
Thales Papagiannakopoulos
10:00 AM - 10:30 AM
IL-17 - neuropeptide first, cytokine second?
Lydia Lynch
10:30 AM - 11:00 AM
Ischemia in the tumor microenvironment cloaks malignant cells from immune detection
Carlos Carmona-Fontaine
11:00 AM - 12:00 PM
Coffee Break and Poster Viewing
Short Talks
Chair: Tony Ferrante
12:00 PM - 12:15 PM
Lipids drive NK cell metabolic dysfunction in metastatic ovarian cancer patients
Karen Slattery1, Conghui Yao, Rafael J Argüello6, Marcia C Haigis, Donal Brennan3, and Lydia Lynch4,5
12:15 PM - 12:30 PM
Let-7 microRNAs define CD8 T cell fate
Alex Wells, Kaito Hioki, Elena Pobezinskaya, and Leonid Pobezinsky
12:30 PM - 12:45 PM
Interleukin-17 regulates white adipose tissue thermogenesis and promotes high-fat diet induced obesity
Britta Kunkemoeller1, Brenneth Stevens1,2, Amanda Garza1, and Lydia Lynch1,2
12:45 PM - 01:00 PM
Interrogating metabolism of CD4+ T cells on the single-cell level using high-throughput single-cell metabolomics
Luisa Abreu1, Alexander Mattausch2, and Theodore Alexandrov1,2
01:00 PM - 01:15 PM
Antigen affinity-dependent NAD biosynthesis patterns T cell growth and programming during quiescence exit
Lucien Turner and Will Bailis
01:15 PM - 01:30 PM
Engineering Metabolically Weaponized T cell therapies for Solid Tumor Translation
John Cox and John Blazeck
01:30 PM - 01:45 PM
PD-1 is induced on tumor-associated macrophages in obesity to directly restrain anti-tumor immunity
Jackie Bader
01:45 PM - 03:00 PM
Lunch and Informal Discussions
03:30 PM - 07:30 PM
City Tour
07:30 PM - 11:00 PM
Dinner and Informal Discussions

Thursday, May 25

08:00 AM - 09:00 AM
Metabolism and Organ Crosstalk
Chair: Thales Papagiannakopoulos
09:00 AM - 09:30 AM
Interactions among Immunometabolism, Adipose Tissue Biology and Metabolic Function in People
Samuel Klein
09:30 AM - 10:00 AM
Broad transcriptomic responses to feeding mimic circadian transcriptomics and provide a robust roadmap for cellular and tissue metabolism
Steven Shoelson, Jia You, Hirobumi Igawa, Giulio Romeo, Jongsoon Lee, and Ai Harashima
10:00 AM - 10:30 AM
Metformin inhibits mitochondrial complex I to lower blood glucose levels
Navdeep Chandel
10:30 AM - 11:30 AM
Coffee Break and Poster Viewing
Short Talks
Chair: Carlos Carmona-Fontaine
11:30 AM - 11:45 AM
Rewiring of lipid metabolism upon sensing of fungal melanin is an essential host defense mechanism in alveolar macrophages
Vassileios Nidris1,2, Ioannis Morianos1,2, Evangelia Intze1, and Georgios Chamilos1,2
11:45 AM - 12:00 PM
The aspartate-glutamate carrier is a mitochondrial metabolic sensor orchestrating mitochondrial morphology and ultrastructure
Aurora Maracani, Jonathan Lambert, and Luca Scorrano
12:00 PM - 12:15 PM
A commensal metabolism by macrophages to support colonic epithelial homeostasis
Stephanie Fritsch1, Nyamdelger Sukhbaatar1, Karine Koehrer1, Alishan Sahu1, Loan Tran2, Andrea Vogel3, Mario Mazic1, Jayne Wilson1, Stephan Forisch1, Hannah Mayr1, Raimund Oberle1, Martin Brenner4, Markus Hengstschläger1, Christine Moissl-Eichinger9, Torben Kuehnast9, Gernot Schabbauer Schabbauer3, Gerda Egger2, Eija Pirinen7, Steven Verhelst6, Wolfram Weckwerth4, Roeland Vanhoutte6, Melanie Hofmann3, and Thomas Weichhart1
12:15 PM - 12:30 PM
De novo sphingolipid synthesis mediates cancer immune evasion by regulating Ifngr1
Mariluz Soula1, Rachel Welch1, Aleksey Chudnovskiy2, Vyom Shah5, Hanan Alwaseem3, Gokhan Unlu1, Paul Bunk5, Vishvak Subramanyam4, Hsi-Wen Yeh1, Artem Khan1, Søren Heissel3, Hani Goodarzi4, Gabriel Victora2, Semir Beyaz5, and Kivanç Birsoy1
12:30 PM - 12:45 PM
Improved metabolic syndrome and timing of weight loss is crucial for influenza vaccine-induced immunity in obesity
Stacey Schultz-Cherry1, Ana Vazquez-Pagan1, Rebekah Honce1, Maureen McGargill2, Benjamin Wilander2, Alexandra Mandarano2, Kristin Wiggins1, and Pam Brigleb1
12:45 PM - 01:00 PM
Distinct high-fat diet regimes distinctly alter immune responses in inflammatory disease.
Sagar Bapat
01:00 PM - 01:15 PM
Tumor microenvironment restricts metabolic and functional response of NK cells
Maxim Nosenko1, Cristhiane Favero de Aguiar1, Barry Moran1, Simon O'Shaughnessy1, Douglas Lamont2, and David Finlay1
01:15 PM - 01:30 PM
Closing Remarks
01:30 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Farewell Dinner

Friday, May 26

08:00 AM - 10:00 AM
10:00 AM - 12:00 PM