15th International Conference on Complement Therapeutics

Program - Tuesday, May 30

Important: The program online is copyrighted to each author and should not be copied and pasted!
  • Aegean Conferences Communication  

    Please note that our registration fees include hotel accommodations and therefore no additional reservations are required. The only communication you should receive is from Aegean Conferences and if your paying by credit card, payment receipts from Conferex LLC. SCAM Alert: Beware of any third party companies calling and/or emailing you to reserve hotel accommodations for you during our conferences


    In completing the online registration form you are not automatically accepted to attend the conference nor are you automatically registered for the conference. Final registration to the conference shall occur after you have been accepted and notified by the conference chair of your acceptance to the conference. If you have been charged the registration fee but your attendance has been declined you will be reimbursed in full.


    Please note that Crete has two airports. You want to arrive at the Chania International Airport (code: CHQ) and take a taxi from the airport to the hotel (~60 EUR). You may also rent a car at the airport and drive to the conference center. Alternatively the other airport (HER) is a two-hour drive to the Conference Center.

    Accommodation Tax

    An accommodation tax of € 4.00 per room night will apply, and will be charged automatically to the individual guest’s extras accounts. 


    Accommodations for the conference are at the Avra Imperial Hotel.  The hotel is located in Kolymbari, 39 km from Chania International Airport, 23 km from the Souda Harbor, and 23 km west of Chania town center.  Please take a taxi from the airport to the conference venue. 

    Arrival and Check-in

    It is expected that attendees will arrive/check-in after 3:00 PM. Anyone arriving after 10:30 pm on the first day should make alternative dinner arrangements.

    Conference Venue

    The Avra Imperial Conference Center is located at the hotel. 

    Handicapped Accessibility

    The site is fully handicapped accessible.

    Oral Presentations

    Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session.  The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A.

    City Tour

    Buses for the city tour will depart from the hotel front lobby at 3:30 pm. Badges are required for participation. 


    Breakfast for registered participants and registered accompanying persons will be served at the Avra Imperial Hotel main restaurant during the hours scheduled in this program. 

    Lunches/Informal Discussions

    Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant and only after the session has finished. Badges are required for admission.

    Dinners/Informal Discussions

    Three of the dinners/informal discussion will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting.  Please contact info@aegeanconferences.org. 

    Internet, Phone, & Computer

    Wireless Internet access is located throughout the conference center free of charge during meeting hours. There are computers available in the hotel’s business center for the use of the attendees. Phone service is available for an additional charge from your hotel room.

    Certificate of Participation

    A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session. 

    Passports and Visa
    Participants are advised to check on their individual requirements before attending any Aegean Conference meeting. Visa applications should be filed at the nearest Greek Embassy in the country in which you are resident, at least three months prior to the anticipated departure date.

    Letters of Invitation
    Letters of invitation to attend an Aegean Conference meeting will be issued only to:

    • Authors of accepted abstracts
    • Fully paid registrants

    Note: Invitations are issued at the discretion of Aegean Conferences, and requests for letters will be accepted only 60 days prior to the conference start date.

    Liability and Insurance
    Neither the organizers, nor the Aegean Conferences will assume any responsibility whatsoever for damage or injury to persons or property during meeting period. Participants are advised to arrange their own personal travel and health insurance.  

    Other Information

    Animals are not permitted on site.

    Badges are required for admission to all events.

    All Aegean Conferences events are non-smoking.

    No Photographs and Recording Devices

    Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations. 

    Code of Conduct Policy 

    Aegean Conferences is committed to making its meetings an inclusive space for sharing ideas and knowledge. The code of conduct can be viewed here. 

Tuesday, May 30

08:00 AM - 09:00 AM
Mechanisms and therapeutic targets in immune-mediated and inflammatory diseases
Chairs: Silvia Guglietta and Paul Morgan
09:00 AM - 09:20 AM
Modulation of lung injury by tissue-specific C3 expression
Hrishikesh S Kulkarni
09:20 AM - 09:40 AM
RNA Profiling and protein expression studies in the synovium of both rheumatoid arthritis and post-traumatic injury identify causal pathogenic mechanisms for complement activation in both diseases
V Michael Holers and Nirmal Banda
09:40 AM - 10:00 AM
Compstatins abolish pathogenic fibroblast function associated with inflammatory tissue priming
Jasna Friscic1, Xi Chen1,2, John D Lambris3, and Markus H Hoffmann1
10:00 AM - 10:20 AM
C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection
Jigar V Desai1, Claudia Kemper2, Ben Afzali4, Jörg Köhl4, and Michail S Lionakis1
10:20 AM - 10:40 AM
Both liver-derived and intracellular complement modulate hematopoietic stem/progenitor cell metabolism and stress response.
10:40 AM - 11:00 AM
Xenotransplantation: Using Genome Editing to Overcome Pig-to-Human Incompatibilities.
Robert Montgomery, Brendan Keating, Alexander Loupy, Nader Moazami, Jeffrey M Stern, Jacqueline I Kim, Massimo Mangiola, Adam Griesemer, Sapna A Mehta, Deane E Smith, and Jef D Boeke
11:00 AM - 11:15 AM
‘Flash’ poster session B
11:15 AM - 11:55 AM
Coffee Break and Poster Viewing
Disease biomarkers and complement diagnostics
Chairs: Veronique Fremeaux-Bacchi and Zoltan Prohaszka
11:55 AM - 12:15 PM
Stratification of patients with complement mediated diseases for complement targeted therapies: the perspective from the diagnostic complement laboratory
Ashley Frazer-Abel 1, Michael Kirschfink 2, and Zoltán Prohászka3
12:15 PM - 12:35 PM
Comprehensive genetic evaluation for the diagnosis of complement alternative pathway-mediated kidney diseases
veronique fremeaux-Bacchi
12:35 PM - 12:50 PM
Ex vivo complement activation on endothelial cells: set up of a new functional tool to explore complement dysregulation
Anna Duval1,3, Marie-Sophie Meuleman1, Lubka Roumenina1, Sophie Caillard2, and Véronique Frémeaux-Bacchi1,3
12:50 PM - 01:05 PM
Identification of genes involved in the protective response of C3aR in amyotrophic lateral sclerosis pathology
Jenny N.T. Fung, John D Lee, and Trent M Woodruff
01:05 PM - 01:20 PM
Distinct cell-bound complement activation products associate with disease activity and immune transcriptional programs in systemic lupus erythematosus
Gabriel R Arguelles, Lynne M Mitchell, Dennis E Hourcade, John P Atkinson, Elisha DO Roberson, and Alfred HJ Kim
01:20 PM - 01:40 PM
Natural antibody targeted complement inhibitor ameliorates the development of chronic heart and lung transplant rejection
Zhenxiao Tu, Changhai Li, Kunal Patel, Stephen Tomlinson, and Carl Atkinson
01:40 PM - 01:50 PM
Closing Remarks - Lubka Roumenina, Dimitrios Mastellos (On behalf of the organizing committee)
01:50 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:00 PM
Informal Discussions
07:30 PM - 11:00 PM
Farewell Dinner