14th International Conference on Complement Therapeutics

Program - Tuesday, June 21

Important: The program online is copyrighted to each author and should not be copied and pasted!
  • Code of conduct

    Aegean Conferences is committed to making its meetings an inclusive space for sharing ideas and knowledge. The code of conduct can be found at:https://www.aegeanconferences.org/src/App/pages/view/AegeanCodeofConduct 


    Accommodations for the conference are at the Sheraton Hotel. The Hotel is located in Ixia, Rhodes, 14.5 km from the airport.

    Arrival and Check-in 

    Attendees are expected to arrive/check-in after 3:00 PM local time. Registered participants arriving after 10:00 PM should make alternative dinner arrangements.  

    Conference Venue

    The Sheraton Conference Center is located at the hotel.  

    Handicapped Accessibility 

    The site is fully handicapped accessible. 

    Oral Presentations

    Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session. The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A. 

    City Tour

    Buses for the city tour will depart from the hotel front lobby 3:00 PM. Badges are required for participation. 


    Breakfast for registered participants and registered accompanying persons will be served at the Sheraton Hotel main restaurant during the hours scheduled in this program.

    Lunches/Informal Discussions

    Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant. Badges are required for admission.

    Dinners/Informal Discussions

    Three of the dinners/informal discussions will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting. 

    Internet, Phone, & Computer 

    Wireless internet access is available throughout the conference center free of charge during meeting hours. 

    Certificate of Participation

    A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session.

    Meeting Room Policy

    Mask Recommendation

    Face masks are recommended indoors.

    No Photographs and Recording Devices 

    Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations. 

    Other Information

    Animals are not permitted on site. 

    Badges are required for admission to all events. 

    All Aegean Conferences events are non-smoking. 


    Aegean Conferences expects attendees to conform their conduct at these meetings to the policies and procedures of their employing institution or company. If we learn of improper conduct by an attendee, we will take appropriate action, including reporting such conduct to the attendee's employing institution or company and barring the attendee from participation in our meetings.

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Tuesday, June 21

08:00 AM - 09:00 AM
Genetic drivers, mechanisms and targets in (auto)-immune and inflammatory diseases
Chairs: Georgios Hajishengallis and Monica Olcina
09:00 AM - 09:20 AM
Is therapeutic complement modulation beneficial after trauma?
Markus Huber-Lang1, Ludmila Lupu1, Marco Mannes1, Lisa Wohlgemuth1, John Lambris2, and Tom Mollnes3
09:20 AM - 09:40 AM
The C5a/C5aR1 axis controls the early IgM to IgG switch of collagen type VII autoantibodies in experimental Pemphigoid Disease
Samyr Kenno1, Sina Borus1, Katja Bieber3, and Jörg Köhl1,
09:40 AM - 10:00 AM
Complement is required for microbe-driven induction of Th17 and periodontitis
Hui Wang1, Hidetaka Ideguchi1, Tetsuhiro Kajikawa1, Dimitrios Mastellos3, John Lambris2, and George Hajishengallis1
10:00 AM - 10:15 AM
Lest we forget: Lessons from complement reactions to oligos, anti drug antibodies and AAV gene therapy.
Ashley Frazer-Abel
10:15 AM - 10:35 AM
Targeted Panels or Exome – Which is the Right NGS Approach for complement-mediated diseases?
veronique Fremeaux-Bacchi
10:35 AM - 10:55 AM
Clinical Xenotransplantation: Implications for Complement Inhibition
Robert Montgomery
10:55 AM - 11:10 AM
Systemic C3 inhibition in a patient with CSMD1 mutation and multi-systemic inflammatory disease.
Jean Francis1, Hamza Hassan1, Josh Korzenik 2, Deepak Rao 2, Jennifer Ho3, David Salant 1, and John Sloan 1
11:10 AM - 11:45 AM
Coffee Break and Poster Viewing
Complement: a multifaceted driver of thromboinflammation
Chairs: Markus Huber-Lang and Wioleta Zelek
11:45 AM - 12:05 PM
Venous air embolism activates complement C3 without corresponding C5 activation and trigger thromboinflammation in pigs
Benjamin Storm1,2,3,4, Judith Ludviksen2, Dorte Christiansen2, Hilde Fure2, Kristin Pettersen2, Anne Landsem2, Bent Nilsen1,4, Knut Dybwik1, Tonje Braaten4,5, Erik Nielsen1,3,4,6, and Tom Mollnes2,6,7,8,9
12:05 PM - 12:20 PM
Complement-induced prothrombotic activation of platelets requires the lysis of cells
Marco Mannes1, Veronika Pechtl2, Christoph Schmidt2, Susanne Hafner2, Vivek Manivel3, Oskar Erkisson3, Kristina Ekdahl3,4, Bo Nilsson3, John Lambris5, and Markus Huber-Lang1
12:20 PM - 12:35 PM
Complement masks Fc regions on HIT immune complexes and prevents their recognition by cellular Fc receptors
Hailey Harris1, Sanjay Khandelwal2, Lubica Rauova3, John Lambris4, Douglas Cines4, Brandon Garcia5, and Gowthami Arepally2
12:35 PM - 12:50 PM
Effects of complement C3, C5 and CD14 inhibitors on bacterial survival and thromboinflammation induced by two different live E.coli-strains in human whole blood
Ole Brekke1,2, Joost Grond1,2, Anne Landsem1, Dorte Christiansen1, Judith Ludviksen1, Corinna Lau1, Trent Woodruff3, John Lambris4, Terje Espevik6, and Tom Mollnes1,2,5,6,7
12:50 PM - 01:05 PM
A preclinical study of a novel ex-vivo cell-coating construct protecting against ischemia/ reperfusion injury in kidney transplantation
Bo Nilsson, Alireza Biglarnia, Kristina Ekdahl, Marianne Jensen, and Yuji Teramura
01:10 PM - 01:40 PM
Live poster session B: 5-min flash talks
01:40 PM - 01:45 PM
Closing Remarks - John D. Lambris
01:45 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 08:00 PM
Informal Discussions
08:00 PM - 11:30 PM
Farewell Dinner