14th International Conference on Complement Therapeutics

Program - Sunday, June 19

Important: The program online is copyrighted to each author and should not be copied and pasted!
  • Code of conduct

    Aegean Conferences is committed to making its meetings an inclusive space for sharing ideas and knowledge. The code of conduct can be found at:https://www.aegeanconferences.org/src/App/pages/view/AegeanCodeofConduct 


    Accommodations for the conference are at the Sheraton Hotel. The Hotel is located in Ixia, Rhodes, 14.5 km from the airport.

    Arrival and Check-in 

    Attendees are expected to arrive/check-in after 3:00 PM local time. Registered participants arriving after 10:00 PM should make alternative dinner arrangements.  

    Conference Venue

    The Sheraton Conference Center is located at the hotel.  

    Handicapped Accessibility 

    The site is fully handicapped accessible. 

    Oral Presentations

    Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session. The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A. 

    City Tour

    Buses for the city tour will depart from the hotel front lobby 3:00 PM. Badges are required for participation. 


    Breakfast for registered participants and registered accompanying persons will be served at the Sheraton Hotel main restaurant during the hours scheduled in this program.

    Lunches/Informal Discussions

    Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant. Badges are required for admission.

    Dinners/Informal Discussions

    Three of the dinners/informal discussions will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting. 

    Internet, Phone, & Computer 

    Wireless internet access is available throughout the conference center free of charge during meeting hours. 

    Certificate of Participation

    A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session.

    Meeting Room Policy

    Mask Recommendation

    Face masks are recommended indoors.

    No Photographs and Recording Devices 

    Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations. 

    Other Information

    Animals are not permitted on site. 

    Badges are required for admission to all events. 

    All Aegean Conferences events are non-smoking. 


    Aegean Conferences expects attendees to conform their conduct at these meetings to the policies and procedures of their employing institution or company. If we learn of improper conduct by an attendee, we will take appropriate action, including reporting such conduct to the attendee's employing institution or company and barring the attendee from participation in our meetings.

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Sunday, June 19

08:00 AM - 09:00 AM
Structural insights and mechanisms of activation, regulation and signaling crosstalk
Chairs: Brian Geisbrecht and Veronique Fremeaux-Bacchi
09:00 AM - 09:20 AM
Structural insights into complement protease complexes
Piet Gros
09:20 AM - 09:40 AM
Modified DNA aptamers as inhibitors of complement proteins and their complexes
Brian Geisbrecht
09:40 AM - 10:00 AM
Activation of the complement system by cholesterol crystals
Terje Espevik1, Nathalie Niyonzima1, Claudia Kemper2, Bente Halvorsen3, and Tom Mollnes4,5
10:00 AM - 10:15 AM
Platelets balance revascularization by anaphylatoxin C5a receptor-dependent release of paracrine factors
Henry Nording1, Antje Luebken1, Tobias Geisler2, and Harald Langer1
10:15 AM - 10:30 AM
Complement activation in intravascular hemolysis relies on heme-depended inactivation of factor I
Alexandra Gerogianni 1, Jordan Dimitrov2, Victoria Poillerat 2, Satheesh Chonat 3, Kerstin Sandholm 1, Karin McAdam4, Kristina Ekdahl 5, Tom Mollnes4, Camilla Mohlin 1, Lubka Roumenina 2, and Per Nilsson 1
10:30 AM - 10:45 AM
Gangliosides as potential complement glycotherapeutics - Fetal death of sialoglycan deficient embryos is independent of C5.
Henri Wedekind1, Arno Fenske1, Andreas Tiede2, Birgit Weinhold1, Anja Münster-Kühnel1, and Markus Abeln1
10:45 AM - 11:05 AM
The intertwined relationship between complement and platelet activation
Harald Langer
11:05 AM - 11:45 AM
Coffee Break and Poster Viewing
Complement in cancer: mechanistic insights and therapeutic concepts
Chairs: Ruben Pio and Lubka Roumenina
11:45 AM - 12:05 PM
Complement-related therapies to treat cancer: where to target?
Ruben Pio
12:05 PM - 12:25 PM
Potentiating anti-CD20 Monoclonal Antibody Therapy by Targeting Complement C3 Activation Fragments Covalently Deposited on Lymphoma Cells
Ronald Taylor1, Margaret Lindorfer1, Adrian Wiestner1, Erika Gaglione2, Sivasubramanian Baskar2, Christoph Rader3, and Haiyong Peng3
12:25 PM - 12:40 PM
Targeting C5aR1 improves radiotherapy by increasing CX3CR1+ macrophage-dependent clearance of apoptotic cells in normal tissue and improving responses in immune-excluded tumours
Callum Beach1, Dominika Majorova 1, David MacLean1, Stavros Melemenidis 3, Mahnaz Damavandi Darvish 4, Dhanya Nambiar3, Ryan Kim3, Kerriann Casey6, Yanyan Jiang1, Eui Jung Moon1, Dadi Jiang, Albert Koong , Simon Buczacki 4, Tim Maughan1, Simon Leedham 2, Edward Graves 3, Quynh-Thu Le3, Trent Woodruff 7, Manuel Stucki 8, Amato Giaccia1, and Monica Olcina1
12:40 PM - 12:55 PM
In situ complementomics reveals intratumoral complement activation, leading to poor prognosis in renal cancer
Margot Revel, Marie Daugan, Marie-Agnès Dragon-Durey, Catherine Sautes-Fridman, Wolf-Herve Fridman, and Lubka Roumenina
12:55 PM - 01:10 PM
Intracellular activation and regulation of the complosome – driver of cancer progression
Alessandra Zarantonello, Margot Revel, Tania Robe-Rybkine, Antonin Bourdin, Catherine Sautes-Fridman, Wolf Herman Fridman, and Lubka Roumenina
01:10 PM - 01:30 PM
Complementome as a driver of (tumor) cell fate
Lubka Roumenina
01:30 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:30 PM
Informal Discussions
07:30 PM - 10:30 PM
Dinner and Informal Discussions