14th International Conference on Genomes, Pathways, and Systems Medicine

Program

Important: The program online is copyrighted to each author and should not be copied and pasted!
  • Code of conduct

    Aegean Conferences is committed to making its meetings an inclusive space for sharing ideas and knowledge. The code of conduct can be found at:https://www.aegeanconferences.org/src/App/pages/view/AegeanCodeofConduct 

    Accommodations

    Accommodations for the conference are at the Sheraton Hotel. The Hotel is located in Ixia, Rhodes, 14.5 km from the airport.

    Arrival and Check-in 

    Attendees are expected to arrive/check-in after 3:00 PM local time. Registered participants arriving after 10:00 PM should make alternative dinner arrangements.  

    Conference Venue

    The Sheraton Conference Center is located at the hotel.  

    Handicapped Accessibility 

    The site is fully handicapped accessible. 

    Oral Presentations

    Speakers are asked to bring their USB flash drive to the reception desk at least 30 minutes prior to the session. The allocated time for all presentations, unless otherwise indicated, includes five minutes Q&A. 

    City Tour

    Buses for the city tour will depart from the hotel front lobby 3:30 PM. Badges are required for participation. 

    Breakfast

    Breakfast for registered participants and registered accompanying persons will be served at the Sheraton Hotel main restaurant during the hours scheduled in this program.

    Lunches/Informal Discussions

    Lunches for registered participants and registered accompanying persons will be served during the times indicated in this program at the main restaurant. Badges are required for admission.

    Dinners/Informal Discussions

    Three of the dinners/informal discussions will be served during the times indicated in the program. Vegetarian entrees are available only upon request in advance of the meeting. 

    Internet, Phone, & Computer 

    Wireless internet access is available throughout the conference center free of charge during meeting hours. 

    Certificate of Participation

    A Certificate of Participation will be distributed to a participant for those sessions that the participant has attended. A participant must attend an entire session to receive credit for that particular session. Late arrivals and early departures from a session will preclude a participant from receiving credit for that session.

    Meeting Room Policy

    Mask Recommendation

    Face masks are recommended indoors.

    No Photographs and Recording Devices 

    Participants are not allowed to photograph and/or record using cameras, mobile telephones and other recording devices during the slide and poster presentations. 

    Other Information

    Animals are not permitted on site. 

    Badges are required for admission to all events. 

    All Aegean Conferences events are non-smoking. 

     

    Aegean Conferences expects attendees to conform their conduct at these meetings to the policies and procedures of their employing institution or company. If we learn of improper conduct by an attendee, we will take appropriate action, including reporting such conduct to the attendee's employing institution or company and barring the attendee from participation in our meetings.

    The Aegean Conferences is committed to protecting the privacy of its visitors. Information that our meeting participants provide or that is derived from internal website tracking is not sold, rented or shared with any individual or organization.  You can let us know that you would prefer not to receive information by e-mail at any time, simply by sending an e-mail to unsubscribe@aegeanconferences.org. If you do so, we will not use your personal information for informing you on our future meetings and other services. 

Wednesday, June 22

06:00 PM - 07:00 PM
Conference Registration
07:00 PM - 10:00 PM
Welcome Reception and Dinner

Thursday, June 23

08:00 AM - 09:00 AM
Breakfast
09:00 AM - 09:10 AM
Welcome and Opening Remarks
3D Chromatin Organization
Chair: Bing Ren
09:10 AM - 09:40 AM
Decoding the non-coding regulatory genome in health and disease
Jim Hughes
09:40 AM - 10:10 AM
Machine learning for single-cell 3D genome analysis
Jian Ma
10:10 AM - 10:40 AM
From A and B compartments to nuclear locales: nuclear structure/function insights from molecular (DamID) and cytological (TSA-seq) proximity assays
Andrew Belmont
10:40 AM - 11:00 AM
BLNK-mediated signaling pathway as a regulator of ErbB2/Her2-driven breast cancer
Xiaoyang Liu1, Sandhya Chipurupalli11, Byong Yoo1, Michael McPhee1, Sina Mazinani1, Giulio Francia2, Robert Kerbel 3, and Kirill Rosen1
11:00 AM - 11:30 AM
Coffee Break and Poster Viewing
Development
Chair: Bing Ren
11:30 AM - 12:00 PM
Mapping Therapeutic Target Space for Treating Dilated Cardiomyopathy
Francesca Briganti, Isaac Perea-Gil, Ioannis Karakikes, and Mark Mercola
12:00 PM - 12:30 PM
The evolution of organ development
Margarida Cardoso-Moreira
12:30 PM - 01:00 PM
Single-cell analyses of bidirectional reprogramming routes reveal differential plasticity of sister pluripotent epiblast and extra-embryonic endoderm states
Vidur Garg1,2, Yang Yang3, Sonja Nowotschin1, Manu Setty3, Ying-Yi Kuo1, Roshan Sharma3, Alexander Polyzos4, Dylan Murphy4, Ada Eralda Salataj4, Amy Jang3, Dana Pe’er3, Effie Apostolou4, and Anna-Katerina Hadjantonakis1,2
01:00 PM - 01:20 PM
Ciliated progenitor cells in human Fallopian tubes from women germline HR deficiency
Sophia George, Ramlogan Sowamber, David Samuels, Andre Pinto, and Matthew Schlumbrecht
01:20 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:15 PM
Informal Discussions
07:15 PM - 10:30 PM
Dinner and Informal Discussions

Friday, June 24

08:00 AM - 09:00 AM
Breakfast
Aging and Age related diseases
Chair: Xiangmin Xu
09:00 AM - 09:30 AM
Making New Neurons to Replenish Lost Ones in Neurodegenerative Disease
Xiang-Dong Fu
09:30 AM - 10:00 AM
Involvement of Retrotransposons in Aging and Age-Related Diseases
John Sedivy
10:00 AM - 10:30 AM
Discovery of risk-reducing alleles using large human genetics data sets
Aris Economides
10:30 AM - 11:00 AM
Single Cell Analysis of Epigenome in Health and Disease
Bing Ren
11:00 AM - 11:30 AM
Coffee Break and Poster Viewing
Cancer Genomics and Epige nomics
Chair: Xiangmin Xu
11:30 AM - 12:00 PM
The Hippo Pathway and Cancer
Kun-Liang Guan
12:00 PM - 12:30 PM
Oncohistones organize canonical PRC1 chromatin architecture to regulate developmental programs
Nada Jabado
12:30 PM - 01:00 PM
Title - TBA
Victoria Seewaldt
01:00 PM - 01:20 PM
HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer
Jindan Yu, Xiaodong Lu, and Jonathan Zhao
01:20 PM - 03:00 PM
Lunch and Informal Discussions
03:00 PM - 07:30 PM
Informal Discussions
07:30 PM - 10:30 PM
Dinner and Informal Discussions

Saturday, June 25

08:00 AM - 09:00 AM
Breakfast
Single C ell M ultiomics
Chair: Aris Economides
09:00 AM - 09:30 AM
Comparative strategies for understanding brain cellular diversity and cell type specific gene regulation using single cell genomics
Ed Lein
09:30 AM - 10:00 AM
TBA
Hongkui Zeng
10:00 AM - 10:30 AM
A multi-omics cell atlas of human healthy and disease kidney.
Kun Zhang
10:30 AM - 11:00 AM
Chromatin structure as a molecular substrate for traces of past life experiences.
Isabelle Mansuy
11:00 AM - 11:30 AM
Mutations Associated with Autism Spectrum Disorder Affect Cohesive and Functionally Interrelated Brain Circuits
Dennis Vitkup
11:30 AM - 12:00 PM
Coffee Break and Poster Viewing
Neural Networks and Function
Chair: Aris Economides
12:00 PM - 12:30 PM
Spatiotemporal dynamics of molecular pathology in ALS-FTD
Hemali Phatnani
12:30 PM - 01:00 PM
TBA
Noel Buckley
01:00 PM - 01:30 PM
Familial Alzheimer’s Disease: epigenetic and transcriptional mechanisms
Shankar Subramaniam
01:30 PM - 02:00 PM
Illuminating learning and memory neural circuits in health and disease
Xiangmin Xu
02:00 PM - 03:30 PM
Lunch and Informal Discussions
03:30 PM - 07:30 PM
City Tour and Discussions
07:30 PM - 10:30 PM
Dinner and Informal Discussions

Sunday, June 26

08:00 AM - 09:00 AM
Breakfast
Systems Biology
Chair: Shankar Subramaniam
09:00 AM - 09:30 AM
High-throughput and multi-dimensional T cell profiling enabled systems immunology
Jenny Jiang
09:30 AM - 10:00 AM
Towards predicting gene expression from sequence
Jussi Taipale
10:00 AM - 10:30 AM
Phenotypic plasticity, the 3rd dimension of phenotypic variation and disease risk
Joseph Nadeau1, Carmen Khoo1, Anya Cutler1, Ildiko Polyak1, Christine Lary1, Chih-Hsiang Yang2, Luca Fagnocchi2, Zach Madaj2, Tim Triche2, and Andrew Pospisilik2
10:30 AM - 10:50 AM
Investigating the molecular link between adipose tissue expansion and metabolic disease risk in the mouse model of Marfanoid Progeroid Lipodystrophy
Minhee Kim1, Trikaldarshi Persaud1, Lawrence Miloscio1, Sujeethraj Koppolu4, Gabor Halasz4, Silvia Smaldone2, Min Ni4, Christina Adler4, Chris Schoenherr3, Katia Karalis1, Giusy Della Gatta1, and Aris Economides1,2,3
10:50 AM - 11:10 AM
A deep clustering approach for separating different levels of cancer risk, using genomic variations in regulatory regions
Dimitris Grigoriadis1, and Artemis Hatzigeorgiou1,
11:10 AM - 12:00 PM
Coffee Break and Poster Viewing
E pigenomics
Chair: Shankar Subramaniam
12:00 PM - 12:30 PM
The sequence determinants of human transcriptional domains: large-scale discovery and systematic perturbations
Lacramioara Bintu
12:30 PM - 01:00 PM
Dynamic chromatin in C. elegans embryos
Susan Mango
01:00 PM - 01:20 PM
Epigenetic mechanisms of information storage in the onset of drug addiction
Luna Zea-Redondo1,2, Warren Winick-Ng1, Eleanor Paul3, Vedran Franke4, Laura Arguedas1, Oscar Marin3, Mark Ungless5, and Ana Pombo1,2
01:20 PM - 01:40 PM
Study of the role of the 3D genome in experience-dependent brain functions
Rodrigo Arzate-Mejia, Nancy Carullo, Leonard Steg, Dimitri Schmid, Francesca Manuella, and Isabelle Mansuy
01:40 PM - 01:50 PM
Closing Remarks
01:50 PM - 03:15 PM
Lunch and Informal Discussions
08:00 PM - 11:30 PM
Farewell Dinner

Monday, June 27

08:00 AM - 10:00 AM
Breakfast
10:00 AM - 12:00 PM
Departure