Tuesday, September 29 |
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6:00 PM |
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Conference Registration |
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8:00 PM |
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Welcome Reception/Dinner |
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Wednesday, September 30 |
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7:30 AM |
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Breakfast |
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9:00 AM |
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Welcome and Opening Remarks |
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Session I |
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Tolerance I Chairs: Steve Miller, Steve Levin |
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9:05 AM |
1 |
Protein modifications in the etiology of autoimmune disease Mark Mamula, Mei-Ling Yang, Kevan Herold and Li Wen |
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9:35 AM |
2 |
Mechanistic study of ODS: an immunomodulatory drug with proven human efficacy Steven D Levin, Le Son Tran, David T Crowe, Kyle A Serikawa, Garry L Redlich, Donald C Foster, and Ian S Frazer |
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10:05 AM |
3 |
MARCO-targeting carboxylated PLG nanoparticles promote therapeutic tolerance induction and suppression of inflammatory monocytes Stephen Miller, Zoe Hunter, Derrick McCarthy, Christopher Harp, Rachael Terry, Suchitra Prasad, Woon-Teck Yap, Nichoas King, Lonnie Shea and Daniel Getts |
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10:35 AM |
4 |
TBA Francesco Quintana |
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11:05 AM |
5 |
Proteolysis-induced defects in B7-H4-mediated negative co-stimulation: the roadmap for the development of Novel biomarker and perspective treatments of Type 1 diabetes-associated autoimmunity Alexei Savinov, Ilian Radichev, Christina Amatya and Maryam Salehi |
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11:20 AM |
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Coffee Break & Poster Viewing |
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Session II |
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Inflammation I |
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Chairs: Hilde Cheroutre, Vassili Soumelis |
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12:00 PM |
6 |
Thymic stromal lymphopoietin in human allergy and autoimmunity: physiopathological links and underlying mechanisms Vassili Soumelis |
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12:30 PM |
7 |
Immune tolerance at the Mucosal front line: AT cell's perspective Magdalena Baudewijn, Sofia Mayans, Florence Lambolez, Mohammed Husain, Yujun Huang, Ichiro Taniuchi and Hilde Cheroutre |
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1:00 PM |
8 |
Local perturbation of lymph nodes alters the extent and specificity of systemic tolerance Lisa Tostanoski, Yu-Chieh Chiu, Joshua Gammon, Thomas Simon, Jonathan Bromberg and Christopher Jewell |
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1:15 PM |
9 |
Type 1 interferon biology in human and mouse Type 1 Diabetes Sindhu Avrizhagen, Benjamin Looney, Sally Yuan, Clayton Mathews, Chang Quing Xia and Michael Clare-Salzler |
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1:30 PM |
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Lunch/Informal Discussions |
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7:30 PM |
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Dinner/Informal Discussions at a local Greek Restaurant |
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Thursday, October 1 |
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7:30 AM |
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Breakfast |
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Session III |
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Myeloid Cells Chairs: Burkhard Becher, Rick Maizels |
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9:00 AM |
10 |
Targeting Microglia Using the Transcription Factor Sall1 Melanie Greter, Iva Lelios, Xueyang Yu, Burkhard Becher, Ruichi Nishinakamura, and Anne Buttgereit |
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9:30 AM |
11 |
Type 2 immunity to Helminth Parasites: Regulation, regulators and effectors Rick M Maizels, Kara J. Filbey, Yvonne Harcus, Christopher J C Johnston, Danielle J Smyth, James P Hewitson, Katherine A Smith and Henry J McSorley |
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10:00 AM |
12 |
GM-CSF in autoimmunity and immunopathology Burkhard Becher, Andrew Croxford, Sabine Spath, Margit Lanzinger, Sonia Tugues, and Ana Amorin |
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10:30 AM |
13 |
GM-CSF driven expansion of myeloid cells elicits CNS inflammation and neurological deficits Sabine Spath, Bettina Schreiner, Juliana Komuczki, Pawel Pelczar and Burkhard Becher |
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11:00 AM |
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Coffee Break & Poster Viewing |
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Session IV |
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Tolerance II Chairs: Lucy Walker, Dan Campbell |
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11:30 AM |
14 |
Control of CD8+ T cell responses by the signaling adaptor BCAP Daniel J Campbell |
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12:00 PM |
15 |
Generation and maintenance of peripheral regulatory T cells Abul Abbas, Iris Gratz and Michael Rosenblum |
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12:30 PM |
16 |
Coordinated regulation of T and B cells responses by the CTLA-4 pathway Lucy SK Walker |
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1:00 PM |
17 |
Working with pharma to transform your discoveries into medicines Jennifer Bell |
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1:15 PM |
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Lunch/Informal Discussions |
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7:30 PM |
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Dinner/Informal Discussions at a local Greek Restaurant |
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Friday, October 2 |
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7:30 AM |
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Breakfast |
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Session V |
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Tolerance III Chairs: Steven Ziegler, Sergio Lira |
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9:00 AM |
18 |
TBA Steven Ziegler |
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9:30 AM |
19 |
Understanding the impact of flux through the cholesterol biosynthesis pathway in host defense Steven J Bensinger |
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10:00 AM |
20 |
A relapsing-remmiting model of inflammatory bowel disease Sergio A Lira |
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10:30 AM |
21 |
Cellular sources of IL-6 in CNS autoimmunity Thomas Korn |
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11:00 AM |
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Coffee Break and Poster Session |
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Session VI |
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1:00 PM |
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Publishing in Nature Immunology – an editorial perspective Ioana Visan |
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1:30 PM |
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Lunch and Informal Discussions |
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3:30 PM |
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City Tour |
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7:30 PM |
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Dinner and Informal Discussion |
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Saturday, October 3 |
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7:30 AM |
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Breakfast |
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Session VII |
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Inflammation II Chairs: Mitch Kronenberg, Ari Waisman |
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9:00 AM |
23 |
Pathogenic Th2 (Tpath2) cells in airway inflammation Toshinori Nakayama, Yusuke Endo, Kenta Shinoda and Kiyoshi Hirahara |
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9:30 AM |
24 |
Genetic programming of functional subsets of innate-like NKT cells in the thymus Mitchell Kronenberg |
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10:00 AM |
25 |
The role of IL-17 in CNS diseases Tommy Regen, Nir Yogev, Ilgiz Mufazalov, Judith Hauptmann and Ari Waisman |
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10:30 AM |
26 |
Natural CD4+CD25+T regulatory cells (nTreg) cultured with antigen and Th2 cytokines, suppress induction of EAE Suzanne Hodgkinson, Giang Tran, Catherine Robinson, Paul Wilcox, Rachael Hall and Bruce Hall |
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10:45 AM |
27 |
Semaphorin 3a/PlexinA4/Neuropilin-1 form a functional B7-H4 receptor complex Joseph Podojil, Ming-Yi Chiang, William Burke, David Liebenson, Roumen Balabanov, Dario Vignali and Stephen Miller |
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11:00 AM |
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Coffee Break & Poster Viewing |
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Session VIII |
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Therapy Chairs: Frank Nestle, Sergio Quezada |
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11:30 AM |
28 |
TBA Frank Nestle |
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12:00 PM |
29 |
Immune Regulation at the Tumour Site Sergio A. Quezada |
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12:30 PM |
30 |
Disentangling the roles of IL-2 in immune activation and immune suppression Jason Fontenot |
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1:00 PM
1:15 PM |
31 |
Towards the clonotype analysis of alopecia areata-specific, intralesional human CD8+ T-lymphocytes Marta Bertolini, Youhei Uchida, Quingquing Zhou, Alfredo Rossi, Klaus Dornmair and Ralf Paus
Closing Remarks |
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1:30 PM |
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Lunch and Informal Discussions |
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8:00 PM |
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Farewell Dinner |
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Sunday, October 4 |
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7:30 AM |
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Breakfast |
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Departure |
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POSTERS |
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32 |
Autoantibodies as biomarkers of neurolupus Ivana Stiborova, Vlastimil Kral and Stanislava Blazickova |
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33 |
B cell subsets immunophenotyping in patients after splenectomy Vlastimil Kral, Jitka Pohorska, Eva Jilkova, Jarmila Zizkova, Dalibor Jilek and Josef Richter |
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34 |
Dendritic cell homeostasis and functions in autoimmunity revealed by critical requirement of non-canonical NFkB Dunja Mrdjen, Florian Mair and Burkhard Becher |
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35 |
Describing the role of GM-CSF in autoimmune inflammation using novel transgenic mouse strains Juliana Komuczki Komuczki, Sabine Spath, Pawel Pelczar and Burkhard Becher |
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36 |
Differential expression of autophagic genes in adipose tissue in short term of high fat diet Carla Nuñez, Rafaela Marineli, Joseane Morari, Natalia Ribeiro, Guilherme Prado, Andressa Baseggio and Mário Maróstica |
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37 |
Do human γδ T cells contribute to hair biology and pathology? Youhei Uchida, Marta Bertolini, Takuro Kanekura, Alfredo Rossi and Ralf Paus |
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38 |
Elevated MVP levels in patients with Rheumatoid Arthritis Dionysia Marinou, Maria Mavrouli, Athanasios Tsakris and John Routsias |
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39 |
Inflammation skews B cells to an immunoregulatory phenotype in Juvenile inflammatory myopathies Christopher Piper, Meredyth Wilkinson, Juvenile Dermatomyositis Research Group (JDRG), Lucy Wedderburn, Claudia Mauri and Kiran Nistala |
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40 |
Molecular mechanisms of pemphigoid disease elicitation by dipeptidyl peptidase-IV inhibitors Iosifina Doxastaki, Christian Sadik and Detlef Zillikens |
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41 |
NMDA receptor antibody positive encephalitis as a complication of herpes simplex encephalitis: Poor response to immunotherapy and serious long-term deficits Alison Christy and Colin Roberts |
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42 |
Parasitic infestations protection from autoimmunity in EAE is mediated by IL-5 activation of antigen specific CD4+CD25+Treg Suzanne Hodgkinson, Giang Tran, Dent Lindsay, Catherine Robinson, Paul Wilcox and Bruce Hall |
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43 |
Preclinical characterization of JAK1/JAK2 inhibitors for treatment of type 1 diabetes Prerak Trivedi, Kate Graham, Stacey Fynch, Misty Jenkins, Nicholas Scott, Thoams Kay and Helen Thomas |
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44 |
Role of EBI2 in Experimental Autoimmune Encephalomyelitis Florian Wanke, Andrew Croxford, André Heinen, Sonja Moos, Stephanie Firmenich, Yilang Tang, Khalad Karram, Denise Tischner, Sonja Sonja Reißig, Sonja Lacher, Ilgiz Mufazalov, Tanja Kuhlmann, Nina Wettschureck, Andreas Sailer, Klaus Rajewsky, Stefano Casola, Ari Waisman and Florian Kurschus |
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45 |
Serum calprotectin (S100A8/9, MRP8/14) in patients with rheumatoid arthritis: its relation with clinical, laboratory and ultrasound parameters of disease activity Jana Hurnakova, Jakub Zavada, Petra Hanova, Hana Hulejova, Martin Klein, Herman Mann, Olga Sleglova, Marta Olejarova, Sarka Forejtova, Olga Ruzickova, Jiri Vencovsky, Karel Pavelka and Ladislav Senolt |
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46 |
The effect of dichloroacetate on certain glycolytic enzymes and on the signature transcription factors of Th1, Th2, Th17 and Treg in human alloreactive CD4+ T-cells Maria Sounidaki, Theodoros Eleftheriadis, Georgios Pissas and Ioannis Stefanidis |
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47 |
TNFR2 expression by CD4 effector T cells is required to induce full-fledged experimental colitis Xin Chen and Joost Oppenheim |
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48 |
Unraveling the genetic causes of severe autoinflammation and autoimmunity in the gut Nina Serwas, Aydan Kansu, Elisabeth Salzer, Cecilia Dominguez Conde, Rico Ardy, Elisangela Santos-Valente, Zarife Kuloğlu, Arzu Demir, Aytac Yaman, Laura Gamez Diaz, Bodo Grimbacher, Reha Artan, Ersin Sayar, Arzu Ensari, Richard Flavell and Kaan Boztug |
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49 |
Vitamin D influences TREM-2 receptor expression in pulmonary sarcoidosis Milan Buc, Maria Bucova, Magda Suchankova, Elena Tibenska, Ivan Majer, Eva Tedlova and Helena Novosadova |
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