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Friday, June 17 |
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6:00 PM |
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Conference Registration |
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8:00 PM |
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Welcome Reception/Dinner |
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Saturday, June 18 |
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7:30 AM |
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Breakfast |
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9:00 AM |
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Welcome and Opening Remarks |
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Session I: |
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Myelopoiesis and Innate Immunity |
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9:15 AM |
1 |
Functional diversity of macrophage/monocyte subsets Shizuo Akira |
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9:45 AM |
2 |
Apoptotic cell engulfment machinery and Rheumatoid Arthritis Kodi Ravichandran and Sanja Arandjelovic |
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10:15 AM |
3 |
Dickkopf-related protein 1 (Dkk1) exerts immune suppressive effects in cancer by regulating accumulation and function of myeloid derived suppressor cells Roberta Faccio |
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10:45 AM |
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Coffee Break and Poster Viewing |
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Session II: |
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Osteoblasts |
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12:00 PM |
4 |
Argininosuccinate lyase is required for nitric oxide synthase-dependent NO production in coupling osteoblast-osteoclast function Zixue Jin, Jordan Kho, Monica Grover, Brian Dawson, Ming-Ming Jiang, Yuqing Chen, Terry Bertin, and Brendan Lee |
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12:30 PM |
5 |
Growth-associated skeletal progenitor cells Henry Kronenberg |
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1:00 PM |
6 |
Bone marrow niche and hematopoietic stem cell differentiation are regulated by the microbiota Yubin Luo, Guang-liang Chen, Nicole Hannemann, Natacha Ipseiz, Gerhard Kroenke, Stefan Wirtz, Georg Schett, and Aline Bozec |
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1:30 PM |
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Lunch/Informal Discussions |
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7:30 PM |
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Dinner/Informal Discussions at a local Greek Restaurant Buses depart from the hotel lobby at 7:30 PM |
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Sunday, June 19 |
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7:30 AM |
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Breakfast |
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Session III: |
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Immune –Bone Interactions |
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9:00 AM |
7 |
Gamma delta T cells in bone fracture and new insights into the osteoimmune system Hiroshi Takayanagi |
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9:30 AM |
8 |
Pathways that suppress osteoclastogenesis Lionel Ivashkiv |
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10:00 AM |
9 |
Enhancement of bone destruction and tumor growth by Myeloma-Bone interaction Toshio Matsumoto |
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10:30 AM |
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Coffee Break and Poster Viewing |
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Session IV: |
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Bone Marrow Niche |
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12:00 PM |
10 |
Eosinophils and the bone marrow niche Claudia Berek |
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12:30 PM |
11 |
Development of the fetal bone marrow niche Suleyman Coskun |
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1:00 PM |
12 |
Searching for a lymphopoietic niche in bone marrow João Pereira |
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1:30 PM |
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Lunch/Informal Discussions |
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7:30 PM |
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Dinner/Informal Discussions at a local Greek Restaurant Buses depart from the hotel lobby at 7:30 PM |
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Monday, June 20 |
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7:30 AM |
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Breakfast |
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Session V: |
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Osteoclasts |
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9:00 AM |
13 |
Epigenetic regulation of RANKL-induced osteoclastogenesis Sakae Tanaka |
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9:30 AM |
14 |
High fat diet-induced osteoarthritis is mediated by innate immune receptors Evangelia Kalaitzoglou, Jacquelyn Herron, Yao Hu, Erika Barboza, Joanna Hudson, Timothy Griffin, and Mary Beth Humphrey |
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10:00 AM |
15 |
Intracellular replication of staphylococcus aureus in osteoclasts Jennifer Krauss and Deborah Novack |
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10:15 AM |
16 |
The novel role of MICD as a transcriptional regulator in osteoclasts Se Hwan Mun and Kyung-Hyun Park-Min |
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10:30 AM |
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Coffee Break and Poster Viewing |
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Session VI: |
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Osteoclasts |
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11:30 AM |
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Orchestrating the symphony of osteoclastogenesis Yihong Wan |
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12:30 PM |
18 |
The role of the iron-sensing receptor Tfr2 in bone homeostasis Martina Rauner, Ulrike Baschant, Antonella Roetto, Uwe Platzbecker, and Lorenz Hofbauer |
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1:00 PM |
19 |
exFoxp3Th17 cells, a pathogenic CD4+ T cell subset in periodontal disease Masayuki Tsukasaki, Noriko Komatsu, and Hiroshi Takayanagi |
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1:15 PM |
20 |
Alterations in the adaptive immune system correlate with fracture healing outcome Christian Bucher, Claudia Schlundt, Hans-Dieter Volk, Georg Duda, and Katharina Schmidt-Bleek |
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1:30 PM |
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Lunch/Informal Discussions |
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3:00 PM |
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City Tour Buses depart from hotel lobby at 3:00 PM |
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7:30 PM |
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Dinner/Informal Discussions at a local Greek Restaurant Please note buses do not pick-up at the hotel prior to dinner. Dinner proceeds right after the tour |
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Tuesday, June 21 |
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7:30 AM |
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Breakfast |
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Session VII: |
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Up And Coming |
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9:00 AM |
21 |
Microbial signals calibrate mononuclear phagocyte function via modifying the bone marrow niche Andreas Diefenbach |
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9:30 AM |
22 |
The impact of TREM2 in macrophage biology and human diseases Marco Colonna |
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10:00 AM |
23 |
The diversity of antibody effector functions Stylianos Bournazos and Jeffrey Ravetch |
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10:30 AM |
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Coffee Break and Poster Viewing |
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Session VIII: |
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Short Presentations |
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11:15 AM |
24 |
Sepsis-induced osteoblast ablation causes immunosuppression Asuka Terashima, Kazuo Okamoto, Tomoki Nakashima, Shizuo Akira, Koichi Ikuta and Hiroshi Takayanagi |
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11:30 AM |
25 |
Rankl-/- Mesenchymal Stromal Cells have an unexpected osteogenic differentiation defect which is improved by a RANKL-expressing lentiviral vector Ciro Menale, Francesca Schena, Lorenzo Diomede, Lucia Sergi Sergi, Lucia Susani, Antonio Inforzato, Eleonora Palagano, Elisabetta Traggiai, Paolo Vezzoni, Cristina Sobacchi, and Anna Villa |
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11:45 AM |
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Light/TNFSF14 in vivo affects bone remodeling through the regulation osteoprotegerin expression Giacomina Brunetti, Isabella Gigante, Angela Oranger, Graziana Colaianni, Adriana Di Benedetto, Roberto Tamma, Luciana Lippo, Paolo Pignataro, Mariasevera Di Comite, Giorgio Mori, Tamada Koji, Carl Ware, Silvia Colucci, and Maria Grano |
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12:00 PM |
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Low-dose RANKL as a potential therapeutic for postmenopausal osteoporosis Anna Cline-Smith, Elena Shashkova, Jesse Gibbs, Deborah Novack, and Rajeev Aurora |
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12:15 PM |
28 |
Exploring the role of interleukin-18 in bone loss associated with chronic inflammatory bowel disease Corinne Metzger, Anand Narayanan, David Zawieja, and Susan Bloomfield |
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12:30 PM |
29 |
Activation of neutrophils by components of the extracellular polymeric substance of bacterial biofilms Ulrike Dapunt, Matthias Gaida, Susanne Maurer, Eva Meyle, Philippe Fouchard, Birgit Prior, and Gertrud Hänsch |
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12:45 PM |
30 |
Lysyl oxidase promotes osteoclastogenesis via RANKL-dependent pathway Koki Hamada, Masayuki Tsukasaki, Kazuo Okamoto, Noriko Komatsu, and Hiroshi Takayanagi |
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1:00 PM |
31 |
Sclerostin expression in distinct osteolineage cell types differentially regulates hematopoietic stem cell and B lymphocyte development Gabriela Loots, Jamila Bajwa, Deepa Murugesh, Cristal Yee, Aris Economides, and Jennifer Manilay |
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1:15 PM |
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Closing Remarks |
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1:30 PM |
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Lunch/Informal Discussions |
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8:00 PM |
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Farewell Dinner |
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Wednesday, June 22 |
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7:30 AM |
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Breakfast |
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12:00 PM |
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Departure |
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Poster Presentations |
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32 |
Alterations of VEGF and CSF-1 expression following orthodontic biophysical force loading in hyperglycemic diabetic rats Jungsun Moon, Yoon-Ho Choi, Hongil Yoo, Hyun-Mi Ko, Jeong-Tae Koh, Min-Seok Kim, Eun-Joo Lee, and Sun-Hun Kim |
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33 |
Autophagy-linked FYVE containing protein Wdfy3 interacts with TRAF6 and modulates RANKL-induced osteoclastogenesis Dennis Wu, Blaine Christiansen, Ran Gu, Ritu Sarin, Regina Zavodovskaya, Chia-Pei Chen, Konstantinos Zarbalis, and Iannis Adamopoulos |
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34 |
Bone marrow adipogenesis in transgenic mice expression human RANKL Vagelis Rinotas, Maria Papadaki, and Eleni Douni |
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35 |
Can we predict fracture healing outcome early? -Evaluation of Osteoprotegerin, an early inflammatory marker Sabir Ali, Ajai ingh, and Abbas Mahdi |
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36 |
Comparing Orthopaedic Surgical Suture Material Immunogenicity In Vitro Jill Cornish, Alistair Lock, MeiLin Tay, Karen Callon, Dorit Naot, Brendan Coleman, and David Musson |
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37 |
Direct and indirect effects of monosodium urate crystals on osteocyte cell viability and gene expression; is there a role for osteocytes in erosive gout? Ashika Chhana, David Musson, Karen Callon, Dorit Naot, Greg Gamble, Geraldine McCarthy, Jillian Cornish, and Nicola Dalbeth |
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38 |
Dual Role of Cyanidin-3-glucoside on the differentiation of bone cells Seoung Hoon Lee |
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39 |
Dysregulation of ERK signaling leads to the development of osteochondroma-like lesions Marie Wehenkel, Maripat Corr, Clifford Guy, Benjamin Edwards, Spencer Richardson, Christopher Calabrese, Gilles Pagès, Jacques Pouysségur, Peter Vogel, and Maureen McGargill |
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40 |
Ebselen is a potential anti-osteoporosis agent by suppressing receptor activator of nuclear factor kappa-b ligand-induced osteoclast differentiation in vitro and lipopolysaccharide-induced inflammatory bone destruction in vivo Chang Hoon Lee, Jaemin Oh, Jong Min Baek, Ju-Young Kim, and Myeung Su Lee |
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41 |
Ex vivo preservation of drug-resistant patient multiple myeloma cells at the osteoblastic niche Wenting Zhang, Woo Lee, and Jenny Zilberberg |
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42 |
Expression of protease-activated receptor-2 by oral epithelial cells is required for bone loss in Porphyromonas gingivalis-induced periodontitis Nidhish Francis, Charles Pagel, Rob Pike, and Eleanor Mackie |
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43 |
Functional analysis of the gene involved in epigenetic regulation during osteoclastogenesis Shinya Nakamura, Sakae Tanaka, Takeshi Miyamoto, Naohiro Izawa, and Hiroyuki Aburatani |
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44 |
IL-11 acts as an autocrine stimulus during osteoclastogenesis Ulrike Harre, Manuel Gado, and Georg Schett |
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45 |
In vivo activation of Treg cells with a CD28 superagonist prevents and ameliorates chronic destructive arthritis in mice Stephanie Win, Anja Kühl, Tim Sparwasser, Thomas Hünig,and Thomas Kamradt |
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46 |
Inhibitory effect of CXCL 14 in the osteogenic differentiation of periodontal ligament cells Jungsun Moon, Sun-Hun Kim, and Hyun-Mi Ko |
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47 |
Inhibitory Effects of Tacrolimus on the IL-1- and endoplasmic reticulum (ER) stress-mediated osteoclastogenesis and inflammation Han-Gyul Yoo, Wan Hee Yoo, MyeungSu Lee, Yong-Wook Park, and Hanbin Yoo |
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48 |
Interaction between magnesium-based implant and cells of the musculoskeletal system Bérengère Luthringer, Maria Costantino, Lili Wu, and Regine Willumeit-Römer |
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49 |
Leptin protects articular chondrocytes from cytotoxic cytokine induced by TNF-a in vivo animal model Sang Yeob Lee, Sung Won Lee, and Won Tae Chung |
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50 |
microRNA profiles in ankylosing spondylitis Taejong Kim, Hye-Mi Jin, Young-Nan Cho, Seung-Jung Kee, and Yong-Wook Park |
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51 |
Non-enzymatic omega-3-fatty acid breakdown products are differentially expressed in rheumatoid arthritis and suppress NFκB activity to inhibit osteoclast formation Lynett Danks, Seint T Lwin, Joshua Brooks, Karin E Lundberg, Ginger Milne, and James R Edwards |
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52 |
NR4a1 is a crucial regulator of bone homeostasis and osteoclast motility Carina Scholtysek, Natach Ipseiz, Brenda Krishnacoumar, Katrin Palumbo-Zerr, Jan Tuckermann, Martin Hermann, Georg Schett, and Gerhar Krönke |
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53 |
Osteocyte-specific ablation of the hypoxia inducible factor regulator VHL alters hematopoiesis in the bone marrow Jennifer Manilay, Jamila Bajwa, Cameron Carlisle, Deepa Murugesh, Cristal Yee, Gabriela Loots, Damian Genetos, and Clare Yellowley |
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54 |
Osteoimmunological interactions and expression profile in osteoporotic transgenic mice overexpressing human RANKL Maria Papadaki, Vagelis Rinotas, Lenka Plestilova, George Kollias, Astrid Jüngel, and Eleni Douni |
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55 |
Ratio of CD8+ effector T cells and regulatory T cells determines the outcome in fracture healing Claudia Schlundt, Hanna Schell, Christian Bucher, Hans-Dieter Volk, Georg Duda, and Katharina Schmidt-Bleek |
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56 |
Relationship between Periodontal Disease and Rheumatoid Arthritis of the bone Surena Vahabi and Abdorahman Gazaleh Rostamian Baniebrahimi |
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57 |
Role of CrkII signaling in RANKL-induced osteoclast differentiation and function Seung-Jung Kee, Jung Ha Kim, Semun Seong, Yong-Wook Park, and Nacksung Kim |
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58 |
Role of dipeptidyl peptidase 3 in bone and immune system: a new osteoimmunological player Ciro Menale, Eleonora Palagano, Harry Blair, Antonella Forlino, Rosita Rigoni, Stefano Mantero, Marta Monari, Paolo Vezzoni, Barbara Cassani, Anna Villa, and Cristina Sobacchi |
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59 |
Screening novel bone graft scaffolds for immunogenicity in vitro David Musson, Alistair Lock, Karen Callon, Dorit Naot, and Jill Cornish |
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60 |
Sirtuin 3 maintains bone homeostasis by regulating AMPK-PGC-1b axis in mice Jeong-Eun Huh, Seoung Hoon Lee, Yongwon Choi, Hyun Seok Kim, and Soo Young Lee |
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61 |
Suppression of inflammation and bone destruction in collagen induced arthritis mice by aGalCer-stimulated natural killer T cells Seung-Jung Kee, Nacksung Kim, Wan-Hee Yoo, Hye-Mi Jin, Young-Nan Cho, and Yong-Wook Park |
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62 |
The effects of switching from teriparatide to anti-RANKL antibody on bone metabolism Toshinobu Omiya, Jun Hirose, Yuho Kadono, Yasunori Omata, Kumiko Ono, Naohiro Izawa, Takeshi Miyamoto, and Sakae Tanaka |
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63 |
The iron sensing receptor Tfr2 regulates the osteohematopoietic niche Ulrike Baschant, Martina Rauner, Uwe Platzbecker, and Lorenz Hofbauer |
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64 |
The role of the oxidative burst in bone remodeling during chronic inflammation Christine Czegley, Christine Schauer, Carina Scholtysek, Gerhard Krönke, Georg Schett, Martin Herrmann, and Markus Hoffmann |
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65 |
The Syk tyrosine kinase regulates in vivo bone homeostasis Daniel Csete, David Győri, Shigeaki Kato, Alexander Tarakhovsky, and Attila Mócsai |
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66 |
Utility of Toll-like receptor pattern as biomarkers for deep joint infection in total joint arthroplasty Regina Fillerova, Anna Petrackova, Petr Gajdos, Milos Kudelka, Jiri Gallo, and Eva Kriegova |
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67 |
WNT signaling inhibitors as promising diagnostic serum markers of osteolytic bone metastasis Emanuela Galliera, Monica Marazzi, Lorenzo Drago, Giuseppe Banfi, Alessandro Luzzati, and Massimiliano Corsi Romanelli |