First International Conference on Oral Mucosal Immunity and Microbiome

Preliminary Program

Wednesday, September 26

     

6:00 PM

 

Conference Registration

     

8:00 PM

 

Welcome Reception and Dinner

     

Thursday, September 27

     

8:00 AM

 

Breakfast

     
   

Welcome and Opening Remarks

8:45 AM

1

A new era in oral mucosal immunity and the microbiome - opening address

Georgios Belibasakis

     

SESSION I

Mucosal barrier immunity

Chairs: Georgios Belibasakis and Georgios Hajishengallis

9:00 AM

2

Mutual interplays between γδT cells and microbiota orchestrate oral mucosal homeostasis

Avi-Hai Hovav

9:25 AM

3

Interstitial Th17 and Treg plasticity after mucosal P. gingivalis colonization

Massimo Costalonga, Peter Bittner-Eddy, and Lori Fischer

9:50 AM

4

Immunobiology of MAIT cells in the buccal mucosa

Johan Sandberg

10:15 AM

5

Contribution of the innate defense system to the maintenance of periodontal homeostasis 

Richard Darveau, Ana Chang, Jeff McLean, and Nutthapong   Kantrong

10:40 AM

6

Dysbiotic microbiome triggers Th17 cells that mediate oral mucosal immunopathology in mice and humans

Nicolas Dutzan, Tetsujiro Kajikawa, Loreto Abusleme, Teresa Greenwell-Wild, Alexadra Freeman, Patricia Diaz, Steven Holland, George Hajishengallis, and Niki Moutsopoulos

     

11:05 AM

 

Coffee Break

     

SESSION II

Host response and Inflammation

Chairs: Mike Curtis and Nagihan Bostanci

11:30 AM

7

Periodontal tissue inflammation and homeostasis

George Hajishengallis

11:55 AM

8

Understanding susceptibility to periodontal disease through the study of rare-genetic diseases

Niki Moutsopoulos, George Hajishengallis, and Steven Holland

12:20 PM

9

Effect of Streptococcus oralis on a novel three dimensional implant-mucosa model

Carina Mikolai, Alexandra Ingendoh-Tsakmakidis, Andreas Winkel, Christine Falk, Angela Rossi, Heike Walles, and Meike Stiesch

12:45 PM

10

The role of Notch-1/PLA2-IIA axis in P. gingivalis-modulated oral epithelial innate responses

Ahmad Al-Attar, Yelena Alimova, Sreenatha Kirakodu, Anastasia Kozal, Michael Novak, Arnold Stromberg, Luis Orraca, Janis Gonzalez-Martinez, Jeffrey Ebersole, and Octavio Gonzalez

1:10 PM

11

Biofilm induced Profiles of Immune Response Gene Expression by Oral Epithelial Cells

Jeffrey Ebersole

1:35 PM

12

From tooth to tumor, cancer acceleration by Fusobacterium nucleatum

Bachrach Gilad, Naseem Maalouf, Jawad Abed, Lishay Parhi, and Amjad Shehadeh

     

2:00 PM

 

Lunch and Informal Discussions

     

7:30 PM

 

Dinner and Informal Discussions

Buses depart from the hotel lobby at 7:30 PM

     

Friday, September 28

     

8:00 AM

 

Breakfast

     

SESSION III

Microbiome in homeostasis and dysbiosis

Chairs: Richard Darveau and Jorge Frias-Lopez

9:00 AM

13

Mechanisms of dysbiosis – are we too host centric in our view?

Mike Curtis

9:25 AM

14

Interbacterial communication defines oral polymicrobial synergy and dysbiosis

Richard Lamont

9:50 AM

15

Role of Dysbiotic Oral Microbiota in Expansion of Inflammatory Dendritic Cells and Treg to Th17 Conversion in Humans with Periodontitis

Mythilypriya Rajendran, Stephen Looney, Cristiano Susin, Roger Arce, and Christopher Cutler

10:15 AM

16

Microbiota-induced tonic type I interferons instruct a transcriptional, epigenetic and metabolic program that defines the basal state of dendritic cells

Andreas Diefenbach

10:40 AM

17

Commensals, pathobionts and pathogens: lessons learnt from a gnotobiotic mouse model of colitis

Christoph Mueller

     

11:05 AM

 

Coffee Break

     

SESSION IV

Fungal and viral pathogenesis

Chairs: Sinem Esra Sahingur and Wim Crielaard

11:30 AM

18

Interplay of C. albicans with mucosa-associated bacteria in health and disease

Martinna Bertolini, Amit Ranjan, Angela Thompson, Takanori Sobue, and Anna Dongari-Bagtzoglou

11:55 AM

19

Epithelial immune activation by candidalysin

Julian Naglik

12:20 PM

20

Bacterial-fungal interactions in severe childhood tooth-decay

Hyun Koo

12:45 PM

21

Oral microbiota in youth with perinatally acquired HIV infection

Bruce J Paster

1:10 PM

22

Salivary Microbiota of HIV infected, HIV exposed but uninfected, and HI-uninfected and unexposed Nigerian Children

Modupe Coker, Samer El, Patricia Langenberg, Paul Akhigbe, Ozo Obuekwe, Lauren Hittle, Cyril Enwonwu, William Blattner, Emmanuel Mongodin, and Manhattan Charurat

     

1:35 PM

 

Lunch and Informal Discussions

     

7:30 PM

 

Dinner and Informal Discussions

Buses depart from the hotel lobby at 7:30 PM

     

Saturday, September 29

     

8:00 AM

 

Breakfast

     

SESSION V

Oral microbiome and proteome

Chairs: Flavia Teles and Yiping Han

9:00 AM

23

Periodontal disease through the specs of shotgun proteomics

Nagihan Bostanci

9:25 AM

24

The metatranscriptome of periodontitis progression

Jorge Frias-Lopez

9:50 AM

25

Searching deep and wide: insights and progress in the molecular understanding of chronic periodontitis

Kimon Divaris

10:15 AM

26

Lessons learned in 10 years of microbiome research

Egija Zaura

10:40 AM

27

Relative contributions of host genotype and environment to shaping the oral microbiome

Purnima Kumar

11:05 AM

28

Resilience and dynamics of the oral microbiome

Wim Crielaard

     

11:30 AM

 

Coffee Break

     

SESSION VI

Microbial virulence and biofilms

Chairs: Silvia Uriarte and Purnima Kumar

11:55 AM

29

Aggregatibacter colonization, host modulation and metabolic interactions obtained from a barrel of monkeys

Daniel Fine, Vandana Sampathkumar, Senthil Velusamy, and Bruce Paster

12:20 PM

30

Sympatric and allopatric polymicrobial interactions alter pathogen gene essentiality

Marvin Whiteley and Gina Lewin

12:45 PM

31

Life of Porphyromonas gingivalis in the oral mucosa through the looking glass

Ozlem Yilmaz

1:10 PM

32

Genetic lineages of oral treponemes associated with periodontal health and disease

Rory Watt, Xiaolin Yu, Yuki Chan, Wenling Gao, Yong-biao Huo, E. Keung Leung, and Hui-hui Zeng

1:35 PM

33

Survival strategies of Tannerella forsythia within the oral cavity

Ashu Sharma

     

2:00 PM

 

Lunch and Informal Discussions

     

3:30 PM

 

City Tour

Buses depart from hotel lobby at 3:30 PM

     

8:00 PM

 

Dinner and Informal Discussions

Please note that buses do not pick-up at the hotel prior to dinner.

Dinner proceeds right after the tour

     

Sunday, September 30

     

8:00 AM

 

Breakfast

     

SESSION VII

Microbiome, cancer and systemic disease

Chairs: Egija Zaura and Kimon Divaris

9:00 AM

34

Isolation of as yet uncultured oral bacteria

William Wade

9:25 AM

35

Oral cancer susceptibility and  the oral microbiome: Rare insights from Fanconi Anemia

Flavia Teles, Kevin Moss, Michele Patel, Janet Doolittle-Hall, and Lynn Martin

9:50 AM

36

Omega−3 fatty acids protect fetuses from Fusobacterium nucleatum-induced placental Inflammation originating from maternal endothelial cells

Yiping Han

10:15 AM

37

Dysbiotic oral microbiota and an impaired epithelial barrier cause focal lymphocytic sialadenitis in Sjogren’s syndrome

Youngnim Choi

10:40 AM

38

A scientific reason for not looking a gift horse in the mouth: Periodontitis and the route to pathology of systemic diseases

Jan Potempa

     

11:05 AM

 

Coffee Break

     

SESSION VIII

Microbiota and inflammation

Chairs: Jeffrey Ebersole and Niki Moutsopoulos

11:30 AM

39

Neutrophil interaction with emerging oral pathogens: a novel view of the disease paradigm

Silvia Uriarte

11:55 AM

40

Role of lymphocytes in type 2 diabetes-potentiated periodontitis

Barbara Nikolajczyk

12:20 PM

41

Diabetes alters the oral microbiome through an IL-17 mediated mechanism

Dana Graves

12:45 PM

42

Targeting inflammation: Insights into the function of A20 in the oral mucosa

Sinem Sahingur, Yajie Li, Erin Mooney, Xia_Juan Xia, and Sara Holden

1:10 PM

43

Role of microbiome–mucosa cross-talk in chemotherapy-induced oral mucositis

Patricia Diaz

1:35 PM

44

treatment of murine periodontitis via local induction of M2 macrophages

Mostafa Shehabeldin, Gin Gao, Ashlee Greene, Zhe  Zhuang, Sayuri Yoshizawa, Steven Little, and Charles Sfeir

     

1:50 PM

 

Closing Remarks

     

2:00 PM

 

Lunch and Informal Discussions

     

8:00 M

 

Farewell Dinner

     

Monday, October 1

     

8:00 AM

 

Breakfast

     
   

Departure