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Saturday, October 12 |
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7:00 PM |
Conference Registration |
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8:00 PM |
Welcome Reception / Dinner |
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Sunday, October 13 |
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7:30 AM |
Breakfast |
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8:25 AM |
Welcome / Opening Remarks |
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SESSION I |
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8:30 AM |
1 |
Understanding Multiple Sclerosis progression using translational and reverse-translational approaches Olga Rojas, Ann-Katrin Proebstel, Valeria Ramaglia, Angela Wang, Amit Bar-Or, Alex Prat, Sergio Baranzini, and Jennifer Gommerman |
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9:00 AM |
2 |
The role of diet in the development of colitis Sergio Lira |
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9:30 AM |
3 |
Treatment of experimental autoimmune encephalomyelitis with nucleoside-modified mRNA coding for disease-related autoantigens Christina Krienke, Laura Kolb, Elif Diken, Michael Streuber, and Ugur Sahin |
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9:45 AM |
4 |
Susac syndrome as a CD8+ T-cell-mediated endotheliopathy of the central nervous system Roland Liblau |
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10:15 AM |
5 |
Maintenance of regulatory T cell identity at sites of inflammation through epigenetic imprinting Thomas Korn |
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10:45 AM |
Coffee Break |
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SESSION II |
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11:15 AM |
6 |
Generation of memory T helper cells and regulation of airway inflammation Toshinori Nakayama |
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11:45 PM |
7 |
Infection-induced changes in the immune system and their impact on disease susceptibility Michelle Schorer, Tamas Dolowschiak, Nikolas Rakebandt, and Nicole Joller |
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12:15 PM |
8 |
Foxp3-specific deletion of CREB generates ST-2 positive regulatory T-cells with enhanced IL-10 production and suppressive capacity Klaus Tenbrock |
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12:30 PM |
9 |
Exon 2 of the Foxp3 gene regulates IgE-mediated cutaneous autoimmunity after ultraviolet-B light challenge Phillip Domeier, Sarah E. Chang, Sabine Spath, Paul J. Utz, Baohua Zhou, and Steve Ziegler |
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1:00 PM |
10 |
TBD Yasmine Belkaid |
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1:30 PM |
Lunch and Informal Discussions |
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7:30 PM |
Dinner and Informal Discussions Buses depart from the hotel lobby at 7:30 PM |
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Monday, October 14 |
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7:30 AM |
Breakfast |
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SESSION III |
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8:30 AM |
11 |
Cytokine regulation of brain macrophages Melanie Greter |
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9:00 AM |
12 |
Probing the IL10 axis in Gut and Brain Macrophage Biana Bernshtein, Anat Shemer, Zhana Haimon, and Steffen Jung |
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9:30 AM |
13 |
Nucleic acid recognition through cGAS/STING aggravates ANCA-associated vasculitis in the lung Susanne Viehmann, Nina Kessler, Christine Schmidt, Daniela Klaus, Hella Luksch, Simon Otten, Peter Boor, Calvin Krollmann, Lino Teichmann, Angela Rösen-Wolff, Peter Heeringa, Natalio Garbi, and Christian Kurts |
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9:45 AM |
14 |
TLR signaling, monocyte differentiation, and macrophage activation syndrome Jessica Hamerman, Holly Akilesh, Matthew Buechler, Jeffrey Duggan, Bharati Matta, Scott Presnell, Keith Elkon, Adam Lacy-Hulbert, Betsy Barnes, and Marion Pepper |
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10:15 AM |
15 |
Macrophage and dendritic cell biology Florent Ginhoux |
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10:45 AM |
Coffee Break |
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SESSION IV |
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11:15 AM |
16 |
Human T cells subsets in immunity and autoimmunity Federica Sallusto |
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11:45 AM |
17 |
Manipulating the IL-2 pathway for control of autoimmunity Daniel J Campbell, Liliane Khoryati, Minh Pham, Erika Hayes, and Marc Gavin |
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12:15 PM |
18 |
The protective role of IL-12 in psoriasis Pascale Zwicky, Myrto Andreadou, Sarah Mundt, and Burkhard Becher |
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12:30 PM |
19 |
X-chromosome inactivation maintenance is perturbed in lymphocytes from human lupus patients and a mouse model of lupus Montserrat Anguera, Bam Paneru, and Camille Syrett |
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1:00 PM |
20 |
Identification of natural regulatory plasma cells Simon Fillatreau |
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1:30 PM |
Lunch and Informal Discussions |
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7:30 PM |
Dinner and Informal Discussions Buses depart from the hotel lobby at 7:30 PM |
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Tuesday, October 15 |
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7:30 AM |
Breakfast |
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SESSION V |
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8:30 AM |
21 |
Connecting autoimmunity and cancer immunity in mice and humans Jeffrey Bluestone |
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9:00 AM |
22 |
Control of Autoimmunity by CTLA-4-dependent Treg function Lucy Walker |
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9:30 AM |
23 |
Circulation of human cutaneous resident memory CD4 T cells Maria Klicznik, Peter Morawski, Barbara Höllbacher, Suraj Varkhande, Samantha Motley, Thomas Duhen, Michael Betts, Daniel Campbell, and Iris Gratz |
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10:00 AM |
24 |
Spontaneous protein crystallization as a driver of immunity Emma Persson, Kenneth Verstraete, Ines Heyndrickx, Helena Aegerter, Elien Gevaert, Jean-Michel Percier, Kim Deswarte, Ann Dansercoer, Koen Verschueren, Delphine Gras, Pascal Chanez, Claus Bachert, Hanne Van Gorp, Hans De Haard, Christophe Blanchetot, Michael Saunders, Hamida Hammad, Savvas Savvides, and Bart Lambrecht |
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10:30 AM |
Coffee Break and Poster Session |
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SESSION VI |
Cellular Immunology |
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12:00 PM |
25 |
Engineering antigen-expressing regulatory T cells to modulate adverse immune responses David Scott |
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12:30 PM |
26 |
IL-17 controls CNS autoimmunity through the intestinal microbiome Ari Waisman |
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1:00 PM |
27 |
Thymic education: Treg formation trumps negative selection Burkhard Becher |
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1:30 PM |
Lunch and Informal Discussions |
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3:30 PM |
City Tour Buses depart from hotel lobby at 3:30 PM |
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7:30 PM |
Dinner and Informal Discussions Please note that buses do not pick-up at the hotel prior to dinner. Dinner proceeds right after the tour |
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Wednesday, October 16 |
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7:30 AM |
Breakfast |
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SESSION VII |
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8:30 AM |
28 |
Targeting Regulatory T cells for Therapeutic Gain: Means and Mechanisms Sergio Quezada |
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9:00 AM |
29 |
Metabolic programs controlling immune cell function Tim Sparwasser |
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9:30 AM |
30 |
Control of human B cell responses by follicular regulatory cells Carola Vinuessa |
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10:00 AM |
31 |
Alpha V integrins and non-canonical autophagy regulate TLR-driven autoimmunity Adam Lacy-Hulbert, Fiona Raso, Sara Sagadiev, Alina Lorant, Sara Sagadiev, Emily Gilbertson, and Mridu Acharya |
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10:15 AM |
32 |
Patients with PIK3CD gain-of-function mutations reveal a critical role for PI3K in controlling multiple stages of B cell tolerance Elissa Deenick, Anthony Lau, Stuart Tangye, and Danielle Avery |
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10:30 AM |
Coffee Break |
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SESSION VIII |
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11:00 AM |
33 |
Regulation of Th17 by IL-17: implications for autoimmunity Rachel Caspi |
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11:30 AM |
34 |
Molecular control of astrocyte pathogenic activities in MS Francisco Quintana |
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12:00 PM |
35 |
Granzyme B: A key contributor to the progression of pemphigoid diseases, a subtype of autoimmune Blistering disorders David Granville, Sho Hiroyasu, Matthew Zeglinski, Ralph Ludwig, Anika Kasprick, Chiharu Tateishi, Wataru Nishie, Daisuke Tsuruta, and Hiroshi Shimizu |
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12:15 PM |
36 |
A high-salt diet compromises the neutrophil response against bacterial infections through metabolic and hormonal perturbations Christian Kurts |
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12:45 PM |
37 |
Modelling T-cell autoimmunity of the CNS grey and white matter Francesca Odoardi |
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1:15 PM |
Closing Remark |
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1:30 PM |
Lunch / Informal Discussions |
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8:00 PM |
Farewell Dinner |
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Thursday, October 17 |
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7:30 AM |
Breakfast |
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Departure |
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POSTERS |
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38 |
Therapeutic blockade of CD40-CD154 interactions suppresses proteinuria in the NZB/W F1 mouse model of lupus nephritis Barbara Nuesslein-Hildesheim, Frederique Lafossas, Grazyna Wieczorek, Melanie Ceci, Swann Gaulis, Giovanni Palla, Katriona McMichael, Enrico Ferrero, and James Rush |
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39 |
Nucleic acid recognition through specific receptors aggravates ANCA-associated vasculitis Christian Kurts |
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40 |
Successful anti-fibrotic treatment of interstitial pneumonia with autoimmune diseases in the basis of molecular pathogenesis Masahito Ebina |
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41 |
The protective role of IL-12 in autoimmune neuroinflammation Myrto Andreadou, Pascale Zwicky, Pascale Eede, Frank Heppner, Sarah Mundt, and Burkhard Becher |
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42 |
Novel aspects of IRAK1 kinase function in autoimmunity Thomas Hoyler, Giulia Ruzzante, Geraldine Zipfel, Anja Scheidegger, Sophie Sarret, Nadja Caesar, Janet Dawson King, Thomas Boulay, Grazyna Wieczorek, Amanda Littlewood-Evans, Pius Loetscher, Stuart Hawtin, and Tobias Junt |
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43 |
Fab-arm exchange dependent autoimmunity in MuSK myasthenia gravis Dana Vergoossen, Yvonne Fillié-Grijpma, Jaap Plomp, Cor Breukel, Elena Dominguez Vega, Christoph Gstöttner, Paul Parren, Silvère van der Maarel, Jan Verschuuren, and Maartje Huijbers |
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44 |
The expanding field of IgG4-mediated autoimmune diseases Maartje Huijbers, Dana Vergoossen, Yvonne Fillié-Grijpma, Jaap Plomp, Silvère van der Maarel, and Jan Verschuuren |
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45 |
Linking the Xist ribonucleoprorein complex to female-biased autoimmune diseases Diana Dou, Yang Zhao, Yanyan Qi, Jin Xu, Anton Wutz, PJ Utz, and Howard Chang |
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46 |
Polymorphonuclear neutrophils and regulatory T lymphocytes (Treg) cooperate to sustain Treg activity but this interaction is altered in rheumatoid arthritis patients Maxime Batignes, François Santinon, Marie-Christophe Boissier, Natacha Bessis, and Patrice Decker |
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47 |
Antigen-encoding bone marrow deletes mature antigen-specific B cells in recipients and inhibits antigen-specific antibody production Raymond Steptoe, Jeremy Brooks, and James Wells |
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48 |
Progression of Cerebellar atrophy in anti-NMDA encephalitis and associated clinical parameters Sang Kun Lee, Woo-Jin Lee, and Soon-Tae Lee |
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49 |
Development of a novel, blocking anti-CD40 monoclonal antibody for kidney transplantation and autoimmune disease James Rush |
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50 |
Mechanism-guided novel therapies for treating inflammatory diseases Sylviane Muller |
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51 |
Autoantibodies against BP180 in bullous pemphigoid, Alzheimer’s disease and multiple sclerosis Jussi Tuusa, Outi Lindgren, Hanna-Mari Tertsunen, Wataru Nishie, Nina Kokkonen, Laura Huilaja, Kentaro Izumi, Sanna-Kaisa Herukka, Jouko Miettunen, Hiroshi Shimizu, Anne Remes, and Kaisa Tasanen |
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52 |
Altered early life exposures due to immigration patterns and autoinflammatory diseases: Evaluation of the T cell immune response to commensal bacteria Ikbel Naouar, Gary Chao, julia Copeland, David S Guttman, Jayne Danska, Philippe Poussier, Ken Croitoru, Ahmed El-Sohemy, Geoffrey Nguyen, Anne Griffiths, Andrew Paterson, John Parkinson, Kathi Wilson, and Jennifer Gommerman |
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53 |
overexpression of NF-κB-inducing kinase (NIK) affects suppressive capacity of regulatory T cells Anna Ebering |
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54 |
The role of IL-34-mediated CSF-1R signalling in tumour development Dilay Cansever and Melanie Greter |
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55 |
CSF1-R signaling regulates CNS macrophage development and function Wiebke Mildenberger, Sebastian G Utz, Burkhard Becher, and Melanie Greter |
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56 |
Biological therapy inhibits autoimmunity in psoriasis Loredana Frasca, Raffaella Palazzo, Rebecca Favaro, Antonio Costanzo, and Roberto Lande |
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57 |
The role of IL-1R signaling in monocyte-derived phagocyte-mediated neuroinflammation Donatella De Feo, Ana Amorim, Friebel Ekaterina, Ari Waisman, Melanie Greter, and Burkhard Becher |