3rd International Conference on Stem Cells

Preliminary Program

Thursday, October 03

6:00 PM

 

Conference Registration

8:00 PM

 

Welcome Reception / Dinner

Friday, October 04

SESSION I

 

ORGANOGENESIS (Chairs- Jefferey Dilworth and Jette Lengefeld)

8:30 AM

1

The molecular and signalling foundation of human naïve pluripotency

Jacob Hanna

8:55 AM

2

Safe and Allo-accepted Pluripotent Stem Cell Line: A Global Source for Off-the-Shelf Therapeutic Cell Products

Andras Nagy

9:20 AM

3

Making blood before a blood stem cell

Jackie Lillis, Kate Fegan, Kathleen McGrath, and James Palis

9:55 AM

4

Renewal and plasticity in oral epithelia 

Ophir Klein

10:20 AM

5

Antagonism between Young and Old transposable elements mediates intra-organism selection in the early human embryo

Manvendra Singh… and Zsuzsanna Izsvák

10:45 AM

 

Coffee Break and Poster Viewing

11:30 AM

6

Single-cell phenotyping reveals heterogeneity among macrophage precursors during embryogenesis

Elvira Mass … and Frederic Geissmann

11:45 AM

7

MAPK/ERK activity regulates kidney size and nephron number via multiple cellular functions

Anneliis Ihermann-Hella… and Satu Kuure

SESSION III

 

AGING (Chairs Claudia Waskow and Antonio del Sol)

12:00 PM

8

B.  

12:25 PM

9

Dietary control of stem cells in physiology and disease

Omer Yilmaz

12:50 PM

10

Understanding muscle stem cell aging 

Pura  Muñoz-Cánoves 

1:15 PM

11

Cell size determines stem cell potential during aging

Jette Lengefeld

1:30 PM

12

Aging-associated decline of energy metabolism limits rejuvenation potential of metformin treatment.

Espada Lilia… and Maria  Ermolaeva

1:55 PM

 

Lunch and Informal Discussions

Saturday, October 05

SESSION IV

 

Hematopoietic Stem Cells (Chairs Marjorie Brand and Elvira Mass)

8:30 AM

13

Regulation of dormant hematopoietic stem cells

Nina  Cabezas-Wallscheid 

8:55 AM

14

Translational control in the regulation of hematopoietic stem cell fate and function

Kristin Hope

9:20 AM

15

New Insights from Experimental Models of De Novo Human Leukemogenesis

Connie Eaves

9:45 AM

16

Hematopoietic stem cell response to acute thrombocytopenia requires signaling through distinct receptor tyrosine kinases

Beáta Ramasz… and Tatyana Grinenko

10:00 AM

17

Absolute quantification of transcription factors in human erythropoiesis reveals principles of transcriptional regulation

Marjorie Brand

10:25 AM

18

Enhancing hematopoiesis from embryonic stem cells through MLL1-induced activation of a Rac/Rho/integrin signaling axis

Patricia Ernst

10:50 AM

 

Coffee Break

SESSION V

 

Stem Cell Niche (Chairs – Jefferey Dilworth and Tatyana Grinenko)

11:20 AM

19

Pathophysiology of muscle stem cell environment

Bénédicte Chazaud

11:45 AM

20

Dlp-Mediated Hh and Wnt Signaling Interdependence Is Critical in the Niche for Germline Stem Cell Progeny Differentiation

Renjun Tu, Bo Duan, Xiaoqing Song, and Ting Xie

12:10 PM

21

Regulation of the mouse skeletal muscle stem cell niche during homestasis and regeneration 

Shahragim Tajbakhsh

12:35 PM

22

Embryonic origin of osteoclasts 

Gulce Percin… and Claudia Waskow

12:50 PM

23

A functional niche for hematopoietic stem cells from mice and human

Claudia Waskow

Sunday, October 06

SESSION VI

 

Neural Stem Cells (Chairs - Marjorie Brand and Laura Kerosuo)

8:30 AM

26

SWI/SNF complex control of neural progenitor cell differentiation

Fangjian Gao… and Diana Hargreaves

8:55 AM

27

Sex and age dependent activation of resident neural precursor cells to promote self-repair of the injured nervous system.

Cindi Morshead 

9:20 AM

28

Efficacy of Human iPSC-derived Interneuron Precursor Cell Grafts for Alleviating Spontaneous Seizures and Related Co-morbidities in a Model of Chronic Temporal Lobe Epilepsy

Ashok Shetty… and Su-Chun Zhang

9:35 AM

29

Neurog2 and Ascl1 co-expression defines a population of Notch ligand-expressing niche cells that control the timing of embryonic cortical neurogenesis

Sisu Han, … and Carol Schuurmans

10:00 AM

30

Human brain organoid models of neural development and disease

Jenny Hsieh

10:25 AM

31

Multiple roles of Fibro/Adipogenic progenitors in homeostasis and regeneration

Fabio Rossi.. and Chihkai  Chang

10:50 AM

 

Coffee Break and Poster Viewing

SESSION VII

 

iPS cells (Chairs - Ondine Cleaver and Satu Kuure)

11:45 AM

32

TBD

Ondine Cleaver

12:10 PM

33

A chromatin-focused CRISPR screen identifies SETD2, a Histone H3K36 methyltransferase, as a barrier to human somatic cell reprogramming 

Burcu Özçimen, …and Tamer Onder

12:25 PM

34

Self-organisation of the mouse and human embryo

Magdalena  Zernicka-Goetz

12:50 PM

1:05 PM

35

Single cell-based computational approach for subpopulation cellular conversion

Antonio  del Sol   

Dissecting the formation and maintenance of the neural crest stem cell niche
Laura Kerosuo Pahlberg

1:20 PM

37

Induced pluripotent stem cell derived basal cells provide a novel source of multi lineage airway epithelial cells

Amy Ryan (Firth)… and Jinghui Gao

1:30 PM

38

Direct reprogramming of iPSCs into glutamatergic neurons: Reconstruction of transcriptional events and integration of epigenetic changes

Muhammad Kaiser Abdul Karim… and Mark Kotter

1:45 PM

 

Lunch and Informal Discussions

3:30 PM

 

City Tour

7:30 PM

 

Dinner and Informal Discussions

     

Monday, October 07

SESSION VIII

 

Disease (Chairs Gulce Percin and Dan Robinson)

8:30 AM

39

Using stem cells to uncover the molecular pathophysiological mechanisms underlying complex neurological disorders

Evan Snyder

8:55 AM

40

Gene correction of LGMD2A patient-specific iPS cells for targeted autologous cell therapy

Rita Perlingeiro

9:20 AM

41

Stem cell-based modelling of complex diseases

Agota Apati

9:45 AM

42

Gene Editing of Cystic Fibrosis Airway Basal Stem Cells

Shingo Suzuki… and Brian Davis

10:00 AM

43

Dysregulation of the epithelial stem cell factor p63 initiates the development of Sjögren’s syndrome

Filipa Pinto… and Makoto Senoo   

     

10:15 AM

10:30 AM

 

Business Meeting

Coffee Break and Poster Viewing

SESSION IX

 

Muscle Regeneration (Chairs Julia von Maltzhan. and Marc Kotter)

11:25 AM

44

Two Critical Checkpoints During Early Activation of Adult Muscle Satellite Cells

Zhenguo Wu

11:50 AM

45

Metabolites Regulating Muscle Stem Cell Biology

Vittorio Sartorelli

12:15 PM

46

Dynamics of muscle stem cells during tissue growth and regeneration

MJ Stec… and Alessandra Saccoa

12:40 PM

47

Fibroadipogenic progenitors in a mouse model for facioscapulohumeral muscular dystrophy

Michael Kyba

1:05 PM

48

Maturation of hiPSC-derived cardiac cell types

Laurie Boyer

1:30 PM

49

Promoter-proximal stalling of RNA-Polymerase II is required for repopulation of the satellite cell niche after muscle injury. 

F. Jeffrey Dilworth

     

1:55 PM

 

Closing Remarks – Kursad Turksen

2:15 PM

 

Lunch and Informal Discussions

8:00 PM

 

Farewell Dinner

     

Tuesday, October 08

8:00 AM

 

Breakfast

10:00 AM

 

Departure

POSTERS

51

Generation and characterization of MafA-GFP reporter lines in a induced pluripotent stem cells background for Islet cell research.

SHAILESH GUPTA, Christian  Honoré, Björn  Magnusson, Marcello  Maresca, Ryan  Hicks, and Jacob  Sjölin

52

Fgf and Wnt signaling pathways intersect in the mesenchymal niche of the hair follicle to regulate the hair cycle clock

Sarina Harshuk-Shabso, Hila Dressler, Emil Aamar, and David Enshell-Seijffers

53

An Engineered Multicellular Stem Cell Niche for the  3D Derivation of Human Myogenic Progenitors from iPSCs

Omid Mashinchian

54

Autologous mesenchymal/stromal stem cells therapy modulates immune response in multiple sclerosis patients 

Maryna Zafranskaya, Alexander Fedulov, Alexei Borisov, Mariya Yurkevich, Svetlana Krivenko, and Darya Nizheharodava

55

Multipotent mesenchymal stromal cells migration on rotenone-induced rat model of Parkinson's disease

Darya Nizheharodava, Natallia Aleinikava, Tatsiana Kuznetsova, Marharyta Vanslau, Alexandr  Boika, Tatsiana Ihnatovich, Vladimir Ponomarev, and Maryna Zafranskaya

56

Expression of Fibrogenesis Markers after Mesenchymal Stem Cell Therapy for Experimental Liver Cirrhosis and Acute Kidney Injury 

Maryna  Zafranskaya, Tatsiana  Ihnatovich, Mikalai Halabarodzka, Tatsiana Savitskaya, and Darya  Nizheharodava

57

Treatment with human induced pluripotent stem cell-derived neural precursors has a beneficial effect on changes in metabolic spectra after focal brain ischemia in rats.

Nataliya Romanyuk, Daniel Jirak, Natalia Ziolkowska, Karolina Turnovcova, Kristyna Karova, and Pavla Jendelova

58

Early erythroid differentiation is closely associated with the progression through S phase

Petr Páral, Martin Báječný, Tomáš Heizer, Luděk Šefc, and Emanuel Nečas

59

Lack of evidence for active role of hematopoietic stem cells in intensive bone marrow regeneration

Kateřina Faltusová, Tomáš Heizer, Martin Báječný, and Emanuel Nečas

60

Lin-Sca-1+c-Kit+ (LSK) cells are altered myeloid progenitors in regenerating bone marrow

Emanuel Nečas, Kateřina Faltusová, Chia-Ling Chen, Martin Báječný, Tomáš Heizer, Petr Páral, and Filipp Savvulidi

61

Human mesenchymal stromal cells derived from different tissues as sources for cell and cell-free therapy, with a focus on neuroregenerative potential 

Irena Vackova, Milada Chudickova, Yuriy Petrenko, Karolina Turnovcova, Kristyna Kekulova, and Sarka Kubinova

62

Neural differentiation and gene expression of human amniotic fluid stem cells derived from healthy and foetus Down syndrome pregnancies 

Aistė Zentelytė, Deimantė Žukauskaitė, Veronika Borutinskaitė, and Rūta Navakauskienė

63

In vitro modelling of cardiac differentiation in DiGeorge syndrome

Tünde Berecz, Andrea Molnár, Brigitta  Szabó, Irén Haltrich, László Homolya, Sian  Harding, János Réthelyi, Béla Merkely, Gábor Földes, and Ágota Apáti

64

MGF and IGF-I have a neuroprotective effect at high glucose concentrations during the time of injury by increasing the proliferation of NSCs 

Tuğba Gürbüz, Selçuk Sözer Tokdemir, Burcu Sarya Tunç, and Kenan  Ateş

65

Dissecting the formation and maintenance of the neural crest stem cell niche

Laura Kerosuo, Ceren  Pajanoja, Jenny Hsin, and Andrew Schiffmacher

66

Programming cell identity: Enabling the next generation of human cell models 

Tüzer  Kalkan, Thomas  Moreau, Imbisaat  Geti, Michael D'Angelo, Fabian  Bachinger, Patrick Rericha, Giacomo Borsari, and Mark  Kotter

67

Stimulation of Human skin derived mesenchymal stromal cell proliferation using a herbal distillate: a pilot study 

Praneeth  Ratnayake, Udaya  Samaratunga, Jayamini Seneviratne, and Preethi Udagama

68

New molecular and cellular insights into the myovascular niche of skeletal muscle satellite cells: role of the sympathetic innervation

Alessio Rotini, Juliette Berthier, Romain Gherardi, Frederic Relaix, and Peggy Lafuste

69

Deciphering the role of human-specific genes in the development of the human neocortex

Fabio Marsoner, Ammar Jabali, Elina Nürnberg, Miriam Wandres, Andrea Rossetti, Thorsten Lau, Mathias Hafner, Philipp Koch, and Julia Ladewig

70

aberrant splicing of the stem cell factor p63 increases susceptibility to tumorigenesis in epithelia

Keshia Pitt, Filipa Pinto, and Makoto Senoo

71

Generation of Lacrimal Gland from Induced Pluripotent Stem Cells

Sinan  Guven, Melis Asal, and Canan Yildirim

72

Deciphering the role of Neurog2-Ascl1 co-expression in the retina

Yacine Touahri, Sisu han, Jiayi Zhao, Hibo Rijal, Matthew  Brooks, Anand Swaroop, and Carol Schuurmans

73

Treatment efficacy of human amniotic stem cells for the kidney damages in type 2 diabetic nephropathy

Xue-Yuan Bai

74

Human mesenchymal stem cell-derived extracellular vesicles attenuate inflammation evoked by focal brain injury in rats

Barbara Lukomska, Sylwia Dabrowska, Anna Andrzejewska, and Miroslaw Janowski