10th International Conference on Autoimmunity: Mechanisms and Novel Treatments

Preliminary Program

October 20, 2022

18:30 PM

Conference registration

19:30 PM

Welcome reception and dinner

Each session consists of invited talks (20 min + 5 min Q&A) and short talks selected from abstracts (12 min + 3 min Q&A)

October 21, 2022

8:00 AM

Breakfast

Session I

T cell differentiation (and gd T cells)

Chairs: Ludger Klein and Immo Prinz

 

8:30 AM

Veit Buchholz - Roads to memory: Studying the regulation of lymphocyte stemness by mapping the fate of single T cells

8:55 AM

Ludger Klein - Determinants of central T cell tolerance

9:20 AM

Immo Prinz - Innate and adaptive gd T cells

9:45 AM

Tim Sparwasser - Targeting mitochondrial metabolism to influence T cell differentiation and function

10:10 AM

Michael Dudek - Metabolite-triggered release of TNF by liver-resident CXCR6 CD8 T cells mediates immune pathology in fatty liver disease

   

10:25

Coffee Break / Poster Session

   

Session II

T cell - B cell interactions

Chairs: Lucy Walker and Jessica Hamerman

   

10:55 AM

Jessica Hamerman - COMPLEXity of antibody-induced IFN in lupus, it’s not all IgG

11:20 AM

Marion Pepper - A role for IL-4 in germinal center selection

11:45 AM

Carola Vinuesa - Lessons from inborn errors of immunity that increase susceptibility to human lupus

12:10 PM

Lucy Walker - Targeting the Achilles heel of costimulation blockade in autoimmunity

12:35 PM

Anna Kolz - T:B cell communication in ectopic lymphoid follicles in CNS autoimmunity

   

12:50 PM

Lunch / Informal Discussions

7:30 PM

Dinner / Informal Discussions

October 22, 2022

8:00 AM

Breakfast

Session III

Neuroinflammation

Chairs: Roland Liblau and Alexander Flügel

   

8:30 AM

Simon Fillatreau - Regulatory plasma cells: A novel cure for established for ongoing CNS autoimmunity

8:55 AM

Alexander Flügel - The lung–brain axis in CNS autoimmunity

9:20 AM

Roland Liblau - Tissue-resident T cells in CNS inflammatory diseases: present at the crime scene and …guilty

9:55 AM

Arek Kendirli - Identification of essential modules regulating T cell migration to the central nervous system in multiple sclerosis

   

10:10

Coffee Break / Poster Session

   

Session IV

Microbiome

Chairs: Jennifer Gommerman and Francisco Quintana

   

10:55 AM

Markus Geuking - The maternal microbiota shapes susceptibility to Type 1 Diabetes

11:20 AM

Sergio Baranzini - The gut microbiome in multiple sclerosis: from observations to mechanisms

11:45 AM

Kathy Mccoy - The role of the microbiome and microbial-derived metabolites in immune regulation

12:10 PM

Francisco Quintana - Environmental control of intestinal inflammation

12:35 PM

Jennifer Gommerman - Integration of Retinoic Acid and Lymphotoxin signals for maintenance of mucosal versus splenic dendritic cells

13:00 PM

Short Talks

   

13:15 PM

Lunch / Informal Discussions

7:30 PM

Dinner / Informal Discussions

   

October 23, 2022

8:00 AM

Breakfast

Session V

Helper T cells

Chairs: Thomas Korn and Nicole Joller

   

8:30 AM

Thomas Korn - Skin and gut imprinted T helper cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity

8:55 AM

Nicole Joller - Viral infections license T helper cells for antigen-independent recruitment and activation

9:20 AM

Bruno Silva-Santos - MicroRNA-mediated regulation of the pathogenicity of effector CD4+ T helper subsets in autoimmune pathology

9:45 AM

Anne Dejean - Role of the transcription factor Eomes in Neuroinflammation

10:10 AM

Betsy Barnes - New implications for IRF5 in T cell-mediated autoimmunity

   

10:25 AM

Coffee Break / Poster Session

   

Session VI

Mononuclear phagocytes

Chairs: Melanie Greter and Burkhard Becher

   

10:55 AM

Burkhard Becher - IFNy and GM-CSF control complementary differentiation programs in  the monocyte to phagocyte transition during tissue inflammation

11:20 AM

Melanie Greter - CNS macrophages and the blood-brain barrier

11:45 AM

Florent Ginhoux - Tissue macrophage heterogeneity

12:10 PM

Sidonia Fagarasan - B cell-derived GABA elicits anti-inflammatory macrophages

12:35 PM

Elsa Roussel - Deciphering the ontogeny and role of fetal macrophages at the blood-placental barrier

12:55 PM

Frederike Ridder - GM-CSF maintains a CD226+ subset of salivary gland tissue resident macrophages during postnatal development

   

13:10 PM

Lunch / Informal Discussions

15:00 PM

City Tour

7:30 PM

Dinner / Informal Discussions

October 24, 2022

8:00 AM

Breakfast

Session III

Regulatory and exhausted T cells

Chairs: Adrian Liston and Dario Vignali

   

8:30 AM

Axel Kallies - Inflammation-dependent differentiation of two distinct regulatory T cell populations in the visceral adipose tissue shapes systemic metabolism

8:55 AM

Juan-Carlos Zuniga-Pflucker - Notch signals in recent thymic emigrant regulatory T cell maturation and functionality

9:20 AM

Adrian Liston - Synthetic delivery of IL2 expands the brain regulatory T cell population and effectively prevents pathological neuroinflammation

9:45 AM

Dario Vignali - AutoreativeCD8+ T cells: impact of exhaustion and LAG3

10:10 AM

Pascale Zwicky - IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation

   

10:25 AM

Coffee Break / Poster Session

   

Session VIII

Lymphatics and barrier-associated cells in immunity

Chairs: Francesca Odoardi and Ari Waisman

   

10:55 AM

Ari Waisman - Inflammatory mediators of the blood barrier permeability

11:20 AM

Stephanie Hugues - Immunomodulatory functions of lymphatic vessels

11:45 AM

Francesca Odoardi - Role of the meninges in CNS autoimmunity

12:10 PM

Oliver Harrison - Investigating commensal-specific immunity in barrier tissues

12:35PM

Georgios Hajishengallis - Maladaptive inflammatory memory in hematopoietic progenitors underlies the comorbidity of rheumatoid arthritis and periodontal disease

   

13:00 PM

Lunch / Informal Discussions

7:30 PM

Farewell dinner

   

October 25, 2022

Breakfast

 

Departure

 
   

Remaining abstracts have been accepted for poster presentation