October 20, 2022 |
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18:30 PM |
Conference registration |
19:30 PM |
Welcome reception and dinner |
Each session consists of invited talks (20 min + 5 min Q&A) and short talks selected from abstracts (12 min + 3 min Q&A) |
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October 21, 2022 |
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8:00 AM |
Breakfast |
Session I |
T cell differentiation (and gd T cells) Chairs: Ludger Klein and Immo Prinz |
8:30 AM |
Veit Buchholz - Roads to memory: Studying the regulation of lymphocyte stemness by mapping the fate of single T cells |
8:55 AM |
Ludger Klein - Determinants of central T cell tolerance |
9:20 AM |
Immo Prinz - Innate and adaptive gd T cells |
9:45 AM |
Tim Sparwasser - Targeting mitochondrial metabolism to influence T cell differentiation and function |
10:10 AM |
Michael Dudek - Metabolite-triggered release of TNF by liver-resident CXCR6 CD8 T cells mediates immune pathology in fatty liver disease |
10:25 |
Coffee Break / Poster Session |
Session II |
T cell - B cell interactions Chairs: Lucy Walker and Jessica Hamerman |
10:55 AM |
Jessica Hamerman - COMPLEXity of antibody-induced IFN in lupus, it’s not all IgG |
11:20 AM |
Marion Pepper - A role for IL-4 in germinal center selection |
11:45 AM |
Carola Vinuesa - Lessons from inborn errors of immunity that increase susceptibility to human lupus |
12:10 PM |
Lucy Walker - Targeting the Achilles heel of costimulation blockade in autoimmunity |
12:35 PM |
Anna Kolz - T:B cell communication in ectopic lymphoid follicles in CNS autoimmunity |
12:50 PM |
Lunch / Informal Discussions |
7:30 PM |
Dinner / Informal Discussions |
October 22, 2022 |
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8:00 AM |
Breakfast |
Session III |
Neuroinflammation Chairs: Roland Liblau and Alexander Flügel |
8:30 AM |
Simon Fillatreau - Regulatory plasma cells: A novel cure for established for ongoing CNS autoimmunity |
8:55 AM |
Alexander Flügel - The lung–brain axis in CNS autoimmunity |
9:20 AM |
Roland Liblau - Tissue-resident T cells in CNS inflammatory diseases: present at the crime scene and …guilty |
9:55 AM |
Arek Kendirli - Identification of essential modules regulating T cell migration to the central nervous system in multiple sclerosis |
10:10 |
Coffee Break / Poster Session |
Session IV |
Microbiome Chairs: Jennifer Gommerman and Francisco Quintana |
10:55 AM |
Markus Geuking - The maternal microbiota shapes susceptibility to Type 1 Diabetes |
11:20 AM |
Sergio Baranzini - The gut microbiome in multiple sclerosis: from observations to mechanisms |
11:45 AM |
Kathy Mccoy - The role of the microbiome and microbial-derived metabolites in immune regulation |
12:10 PM |
Francisco Quintana - Environmental control of intestinal inflammation |
12:35 PM |
Jennifer Gommerman - Integration of Retinoic Acid and Lymphotoxin signals for maintenance of mucosal versus splenic dendritic cells |
13:00 PM |
Short Talks |
13:15 PM |
Lunch / Informal Discussions |
7:30 PM |
Dinner / Informal Discussions |
October 23, 2022 |
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8:00 AM |
Breakfast |
Session V |
Helper T cells Chairs: Thomas Korn and Nicole Joller |
8:30 AM |
Thomas Korn - Skin and gut imprinted T helper cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity |
8:55 AM |
Nicole Joller - Viral infections license T helper cells for antigen-independent recruitment and activation |
9:20 AM |
Bruno Silva-Santos - MicroRNA-mediated regulation of the pathogenicity of effector CD4+ T helper subsets in autoimmune pathology |
9:45 AM |
Anne Dejean - Role of the transcription factor Eomes in Neuroinflammation |
10:10 AM |
Betsy Barnes - New implications for IRF5 in T cell-mediated autoimmunity |
10:25 AM |
Coffee Break / Poster Session |
Session VI |
Mononuclear phagocytes Chairs: Melanie Greter and Burkhard Becher |
10:55 AM |
Burkhard Becher - IFNy and GM-CSF control complementary differentiation programs in the monocyte to phagocyte transition during tissue inflammation |
11:20 AM |
Melanie Greter - CNS macrophages and the blood-brain barrier |
11:45 AM |
Florent Ginhoux - Tissue macrophage heterogeneity |
12:10 PM |
Sidonia Fagarasan - B cell-derived GABA elicits anti-inflammatory macrophages |
12:35 PM |
Elsa Roussel - Deciphering the ontogeny and role of fetal macrophages at the blood-placental barrier |
12:55 PM |
Frederike Ridder - GM-CSF maintains a CD226+ subset of salivary gland tissue resident macrophages during postnatal development |
13:10 PM |
Lunch / Informal Discussions |
15:00 PM |
City Tour |
7:30 PM |
Dinner / Informal Discussions |
October 24, 2022 |
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8:00 AM |
Breakfast |
Session III |
Regulatory and exhausted T cells Chairs: Adrian Liston and Dario Vignali |
8:30 AM |
Axel Kallies - Inflammation-dependent differentiation of two distinct regulatory T cell populations in the visceral adipose tissue shapes systemic metabolism |
8:55 AM |
Juan-Carlos Zuniga-Pflucker - Notch signals in recent thymic emigrant regulatory T cell maturation and functionality |
9:20 AM |
Adrian Liston - Synthetic delivery of IL2 expands the brain regulatory T cell population and effectively prevents pathological neuroinflammation |
9:45 AM |
Dario Vignali - AutoreativeCD8+ T cells: impact of exhaustion and LAG3 |
10:10 AM |
Pascale Zwicky - IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation |
10:25 AM |
Coffee Break / Poster Session |
Session VIII |
Lymphatics and barrier-associated cells in immunity Chairs: Francesca Odoardi and Ari Waisman |
10:55 AM |
Ari Waisman - Inflammatory mediators of the blood barrier permeability |
11:20 AM |
Stephanie Hugues - Immunomodulatory functions of lymphatic vessels |
11:45 AM |
Francesca Odoardi - Role of the meninges in CNS autoimmunity |
12:10 PM |
Oliver Harrison - Investigating commensal-specific immunity in barrier tissues |
12:35PM |
Georgios Hajishengallis - Maladaptive inflammatory memory in hematopoietic progenitors underlies the comorbidity of rheumatoid arthritis and periodontal disease |
13:00 PM |
Lunch / Informal Discussions |
7:30 PM |
Farewell dinner |
October 25, 2022 |
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Breakfast |
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Departure |
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Remaining abstracts have been accepted for poster presentation |