2nd International Conference of Liver Pathobiology: From Bench to Bedside

Authors List

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Author Abstracts
Capitani María Celeste Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
A Mann Derek Platelets hijack neutrophils for pro-tumour polarisation in MASH-HCC
Abdallah Ali Linear ubiquitination protects from liver disease in response to obesity
Adameyko Igor In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Adlat Salah Loss of BRCA2 Sensitizes Hepatocellular Carcinoma to PARP Inhibition with Olaparib
Adori Csaba Embryonic Liver Innervation Regulates Glucose Metabolism and Contributes to Alagille Syndrome Defects
Aguilar-Corominas Laia Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Ajouaou Yousra Epigenetic rewiring of hepatocytes by Eed loss changes hepatocyte identity, liver damage, and fibrosis
Albrecht Wolfgang Pharmaceutical Development and Individual Case Studies for Skepinone-L, a Highly Potent and Selective p38a Inhibitor for the treatment of Advanced Hepatocellular Carcinoma
PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Alguero Nadal Ana The role of the liver microenvironment in Ras driven tumorigenesis
Almendros Isaac Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Almodòvar Xènia Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Andersson Emma Embryonic Liver Innervation Regulates Glucose Metabolism and Contributes to Alagille Syndrome Defects
In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Antczak Philip Linear ubiquitination protects from liver disease in response to obesity
Linear ubiquitination prevents MASLD by preserving adipose tissue integrity during obesity
Araujo Joana Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
Prognostic and Mechanistic Role of the cGAS-STING Pathway in Hepatocellular Carcinoma Pathogenesis
Ariño Silvia Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Armel Hyoubi Linear ubiquitination prevents MASLD by preserving adipose tissue integrity during obesity
Artzt Matthias Understanding mechanisms of biliary fibrosis using periportal liver assembloids
Athwal Varinder Multiomic analyses demonstrate hepatocyte SOX9 loss exacerbates fibrosis and HCC development in the DEN-CCl4 mouse model
Avdi Aikaterini Spatiotemporal Quantification of Disease Biomarkers in the MASLD Spectrum Using Longitudinal Micro-CT Imaging
Bahar Halpern Keren A spatial transcriptomics atlas of live donors reveals unique zonation patterns in the healthy human liver
Bai Yu Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Bao Macus Hao Ran The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Barbian Stefi Lactococcus lactis subspecies cremoris, mitigates metabolic disease and induces hepatoprotection by driving changes in the metabolome between the gut and liver.
Bataller Ramón Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Belicova Lenka In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Berger Hilmar Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Bernstein Galina Hepatic impairment studies for drugs with known hepatobiliary excretion - considerations for dose selection
Bird Thomas Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
Blaess Simone PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Blueher Matthias Linear ubiquitination prevents MASLD by preserving adipose tissue integrity during obesity
Blüher Matthias Linear ubiquitination protects from liver disease in response to obesity
Boldt Karsten PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Bono Elisa vascular control of MASH progression
Borlak Jürgen Genomic insights into FGF21-mediated therapeutic effects in MASLD from 396 patient liver biopsies
Boscá Lisardo Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
Brea Rocio Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
Bregante Javier Understanding mechanisms of biliary fibrosis using periportal liver assembloids
Bugler-Lamb Aimée DeLIVERing in vivo CRISPR screens to study hepatic cell-cell interactions
Cadiou Maelle Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
Prognostic and Mechanistic Role of the cGAS-STING Pathway in Hepatocellular Carcinoma Pathogenesis
Cao Chunmiao Loss of BRCA2 Sensitizes Hepatocellular Carcinoma to PARP Inhibition with Olaparib
Casado Marta Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
Celton-Morizur Séverine Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
Prognostic and Mechanistic Role of the cGAS-STING Pathway in Hepatocellular Carcinoma Pathogenesis
Chaffatt Sade Epigenetic rewiring of hepatocytes by Eed loss changes hepatocyte identity, liver damage, and fibrosis
Chalmers Fiona Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
Chan Cerise Yuen Ki The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Chatzigeorgiou Antonios Spatiotemporal Quantification of Disease Biomarkers in the MASLD Spectrum Using Longitudinal Micro-CT Imaging
Chen Po-Yuan Deep Learning–Driven HCC Morphologic Index from H&E Predicts Survival and Reveals Distinct Clinical and Molecular Phenotypes
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Cheu Jacinth Wing Sum The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Chew Valerie TBA - Valerie Chew
Applying machine learning to identify modulators of immune cell function for targeted therapy in hepatocellular carcinoma
Chiu Yu-Chiao Deep Learning–Driven HCC Morphologic Index from H&E Predicts Survival and Reveals Distinct Clinical and Molecular Phenotypes
Coll Mar Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Corbat Agustin In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Couty Jean-Pierre Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
Prognostic and Mechanistic Role of the cGAS-STING Pathway in Hepatocellular Carcinoma Pathogenesis
Cucarella Carme Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
Curran Ciara Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
D'Antonio Michele vascular control of MASH progression
D'Artista Luana PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
DasGupta Ramanuj Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
Dauch Daniel Pharmaceutical Development and Individual Case Studies for Skepinone-L, a Highly Potent and Selective p38a Inhibitor for the treatment of Advanced Hepatocellular Carcinoma
de Haan Sandra In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
De Hollanda Ana Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Delfino Pietro vascular control of MASH progression
Deng Haijing The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Desdouets Chantal Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
Prognostic and Mechanistic Role of the cGAS-STING Pathway in Hepatocellular Carcinoma Pathogenesis
Ding Huiguo TGF-β serves as a critical signaling determinant of liver progenitor cell fate and function
Dishington Jack Therapeutic targeting of cancer associated fibroblasts may allow for microenvironmental remodelling of immunotherapy resistant hepatocellular carcinoma
Donne Romain Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Dooley Steven Regulation of essential hepatocyte functions and identity by super-enhancers in health and disease
TGF-β serves as a critical signaling determinant of liver progenitor cell fate and function
ECM1 as Tumor Suppressor in Hepatocellular Carcinoma through Inhibition of the Integrin-FAK-YAP axis
A Digital Twin Model Reveals Mechanisms of Liver Fibrosis Patterning
Dowbaj Anna Building Architecture and Complexity in Tissue-Derived Liver Organoids
Understanding mechanisms of biliary fibrosis using periportal liver assembloids
Drasdo Dirk A Digital Twin Model Reveals Mechanisms of Liver Fibrosis Patterning
Ebert Matthias TGF-β serves as a critical signaling determinant of liver progenitor cell fate and function
ECM1 as Tumor Suppressor in Hepatocellular Carcinoma through Inhibition of the Integrin-FAK-YAP axis
Regulation of essential hepatocyte functions and identity by super-enhancers in health and disease
Ellis Ewa Embryonic Liver Innervation Regulates Glucose Metabolism and Contributes to Alagille Syndrome Defects
Fang Jing Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
Prognostic and Mechanistic Role of the cGAS-STING Pathway in Hepatocellular Carcinoma Pathogenesis
Ferrer-Lorente Raquel Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Fischer-Posovszky Pamela Linear ubiquitination prevents MASLD by preserving adipose tissue integrity during obesity
Fischler Björn Embryonic Liver Innervation Regulates Glucose Metabolism and Contributes to Alagille Syndrome Defects
Floetgen Dirk PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Forster Michael Pharmaceutical Development and Individual Case Studies for Skepinone-L, a Highly Potent and Selective p38a Inhibitor for the treatment of Advanced Hepatocellular Carcinoma
PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Francés Daniel Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
Frisén Jonas In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Fuertes-Agudo Marina Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
Fundora Yiliam Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Fusini Matías Ezequiel Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
Gacasan Camilo Anthony Lactococcus lactis subspecies cremoris, mitigates metabolic disease and induces hepatoprotection by driving changes in the metabolome between the gut and liver.
Gadi Abhilash Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Galy-Fauroux Isabelle Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
Prognostic and Mechanistic Role of the cGAS-STING Pathway in Hepatocellular Carcinoma Pathogenesis
Gao Qiang Charting single-cell metabolism co-evolution during liver metastasis
Gardeweg Liane Linear ubiquitination protects from liver disease in response to obesity
Geh Daniel Platelets hijack neutrophils for pro-tumour polarisation in MASH-HCC
Georgaka Sokratia Multiomic analyses demonstrate hepatocyte SOX9 loss exacerbates fibrosis and HCC development in the DEN-CCl4 mouse model
Georgakopoulou Anastasia Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
Giannotta Monica vascular control of MASH progression
Giannousi Eirini Spatiotemporal Quantification of Disease Biomarkers in the MASLD Spectrum Using Longitudinal Micro-CT Imaging
Ginès Pere Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Giustini Leonardo vascular control of MASH progression
Gkika Stamatina Spatiotemporal Quantification of Disease Biomarkers in the MASLD Spectrum Using Longitudinal Micro-CT Imaging
Glass David Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Gohar Sara Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
González-Rodríguez Águeda Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
Grass Alexia Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
Gratacós-Ginès Jordi Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Graupera Isabel Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Greten Tim The Gut Microbiome Controls Liver Tumors via the Vagus Nerve
Griffin James Epigenetic rewiring of hepatocytes by Eed loss changes hepatocyte identity, liver damage, and fibrosis
Guillamón-Thiery Àlex Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Guilliams Martin DeLIVERing in vivo CRISPR screens to study hepatic cell-cell interactions
Haeusler Rebecca The role of transport in metabolism and liver disease – what goes in must go out
Halder Georg TBA - Georg Halder
The role of the liver microenvironment in Ras driven tumorigenesis
Combining RAS and TEAD inhibitors eliminates cholangiocarcinoma
Hammad Seddik TGF-β serves as a critical signaling determinant of liver progenitor cell fate and function
A Digital Twin Model Reveals Mechanisms of Liver Fibrosis Patterning
Hammond Nigel Multiomic analyses demonstrate hepatocyte SOX9 loss exacerbates fibrosis and HCC development in the DEN-CCl4 mouse model
Hankeova Simona Embryonic Liver Innervation Regulates Glucose Metabolism and Contributes to Alagille Syndrome Defects
Harrington Heather Understanding mechanisms of biliary fibrosis using periportal liver assembloids
He Qiyuan Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Embryonic Liver Innervation Regulates Glucose Metabolism and Contributes to Alagille Syndrome Defects
Heikenwälder Mathias TBA - Mathias Heikenwälder
Henderson Neil TBA - Neil Henderson
Henning Melanie PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Herms Queralt Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
HIhn Oliver PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Hildebrandt Ximena Linear ubiquitination prevents MASLD by preserving adipose tissue integrity during obesity
Adipocyte-specific LUBAC deficiency promotes sex-dependent MASLD via adipose tissue-liver crosstalk
Linear ubiquitination protects from liver disease in response to obesity
Hillen Hanne Combining RAS and TEAD inhibitors eliminates cholangiocarcinoma
Hinterleitner Clemens PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Hoffman Anne Linear ubiquitination protects from liver disease in response to obesity
Hoffmann Anne Linear ubiquitination prevents MASLD by preserving adipose tissue integrity during obesity
Huang Chenjun Regulation of essential hepatocyte functions and identity by super-enhancers in health and disease
Hubner Richard Multiomic analyses demonstrate hepatocyte SOX9 loss exacerbates fibrosis and HCC development in the DEN-CCl4 mouse model
Huch Meritxell Understanding mechanisms of biliary fibrosis using periportal liver assembloids
Building Architecture and Complexity in Tissue-Derived Liver Organoids
Hyoubi Armel Linear ubiquitination protects from liver disease in response to obesity
Iannacone Matteo vascular control of MASH progression
Ibarzábal Ainitze Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Inverso Donato vascular control of MASH progression
Isaev Sergey In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Itzkovitz Shalev A spatial transcriptomics atlas of live donors reveals unique zonation patterns in the healthy human liver
Iwakiri Yasuko The hepatic lymphatic system in cholestatic liver disease: Mechanisms and therapeutic potential
Jarboui Mohamed PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Jokl Elliot Multiomic analyses demonstrate hepatocyte SOX9 loss exacerbates fibrosis and HCC development in the DEN-CCl4 mouse model
Jones Dean Lactococcus lactis subspecies cremoris, mitigates metabolic disease and induces hepatoprotection by driving changes in the metabolome between the gut and liver.
Jurado Alicia Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Karin Michael Control of Obesity and Inflammation Driven Liver Cancer by the Dr. Jekyll and Mr Hyde Site-specific Actions of NRF2
Kesikiadou Eleni Combining RAS and TEAD inhibitors eliminates cholangiocarcinoma
Kowalczyk Weronika The role of the liver microenvironment in Ras driven tumorigenesis
Combining RAS and TEAD inhibitors eliminates cholangiocarcinoma
Kronenberger Thales PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Kwan Kenneth Kin Leung The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Lahoz Agustín Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
Landerer Cedric Understanding mechanisms of biliary fibrosis using periportal liver assembloids
Lau Mandy Ho Ying The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Lauer Ulrich Pharmaceutical Development and Individual Case Studies for Skepinone-L, a Highly Potent and Selective p38a Inhibitor for the treatment of Advanced Hepatocellular Carcinoma
Laufer Stefan Pharmaceutical Development and Individual Case Studies for Skepinone-L, a Highly Potent and Selective p38a Inhibitor for the treatment of Advanced Hepatocellular Carcinoma
PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Laura Chiara vascular control of MASH progression
Lazar Enikö In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Lee Markcus NEURL1B is required for mitotic spindle organization during liver regeneration and tumorigenesis
Loss of BRCA2 Sensitizes Hepatocellular Carcinoma to PARP Inhibition with Olaparib
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Legaki Aigli-Ioanna Spatiotemporal Quantification of Disease Biomarkers in the MASLD Spectrum Using Longitudinal Micro-CT Imaging
Lehrich Brandon Ectopic Wnt/β-Catenin Signaling Drives Cyclin-D1 Expression During Early Liver Regeneration
Leslie Jack Therapeutic targeting of cancer associated fibroblasts may allow for microenvironmental remodelling of immunotherapy resistant hepatocellular carcinoma
Platelets hijack neutrophils for pro-tumour polarisation in MASH-HCC
Li Shuo Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Liebe Roman Regulation of essential hepatocyte functions and identity by super-enhancers in health and disease
Lin Tao TGF-β serves as a critical signaling determinant of liver progenitor cell fate and function
Regulation of essential hepatocyte functions and identity by super-enhancers in health and disease
Liu Silvia Ectopic Wnt/β-Catenin Signaling Drives Cyclin-D1 Expression During Early Liver Regeneration
LO    Regina Cheuk-Lam The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
López Nogueroles Marina Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
Lorentz Johan In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Lowe Scott TBA - Scott Lowe
Lozano Anthony MASH selects against antigenic Hepatocellular carcinoma
Luedde Tomdde, A Decision Point between cell death and transdifferentiation in carcinogenesis
Lujambio Amaia MASH selects against antigenic Hepatocellular carcinoma
Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
Lundeberg Joakim In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Luque-Tevar Maria Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
Macchi Filippo Epigenetic Disordering by UHRF1 overexpression Drives Stemness and Senescence Escape in HCC
Magnani Elena Epigenetic Disordering by UHRF1 overexpression Drives Stemness and Senescence Escape in HCC
Mann Derek The ontogeny and therapeutic targeting of immunosuppressive neutrophils in hepatocellular carcinoma.
Marmier Solenne Prognostic and Mechanistic Role of the cGAS-STING Pathway in Hepatocellular Carcinoma Pathogenesis
Martínez-Álvarez Alicia Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Martínez-Sánchez Celia Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Mauron Raphael In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
May Stephanie Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
McEwen Corissa Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Mol Hasse The role of the liver microenvironment in Ras driven tumorigenesis
Monga Satdarshan Deep Learning–Driven HCC Morphologic Index from H&E Predicts Survival and Reveals Distinct Clinical and Molecular Phenotypes
Ectopic Wnt/β-Catenin Signaling Drives Cyclin-D1 Expression During Early Liver Regeneration
Moschopoulou Athina PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Moya Ivan The role of the liver microenvironment in Ras driven tumorigenesis
Muerdter Thomas PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Mullen Clara Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
Müller Miryam Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
Murtuza Baker Syed Multiomic analyses demonstrate hepatocyte SOX9 loss exacerbates fibrosis and HCC development in the DEN-CCl4 mouse model
Mysko Chris Multiomic analyses demonstrate hepatocyte SOX9 loss exacerbates fibrosis and HCC development in the DEN-CCl4 mouse model
Nasir Nurul Jannah Applying machine learning to identify modulators of immune cell function for targeted therapy in hepatocellular carcinoma
Naudin Crystal Lactococcus lactis subspecies cremoris, mitigates metabolic disease and induces hepatoprotection by driving changes in the metabolome between the gut and liver.
Ng  Irene Oi-Lin The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Ni Min Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Nigron Nicole Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Nikolakopoulou Polyxeni Spatiotemporal Quantification of Disease Biomarkers in the MASLD Spectrum Using Longitudinal Micro-CT Imaging
Niksic Armin Building Architecture and Complexity in Tissue-Derived Liver Organoids
Understanding mechanisms of biliary fibrosis using periportal liver assembloids
Nixon Colin Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
Noon Luke Embryonic Liver Innervation Regulates Glucose Metabolism and Contributes to Alagille Syndrome Defects
Ooi Zher Yee The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Ouyang John Applying machine learning to identify modulators of immune cell function for targeted therapy in hepatocellular carcinoma
Pan Long Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
Prognostic and Mechanistic Role of the cGAS-STING Pathway in Hepatocellular Carcinoma Pathogenesis
Pantsar Tatu PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Papadopoulos Grigorios Spatiotemporal Quantification of Disease Biomarkers in the MASLD Spectrum Using Longitudinal Micro-CT Imaging
Papadopoulou Martha-Eliza Spatiotemporal Quantification of Disease Biomarkers in the MASLD Spectrum Using Longitudinal Micro-CT Imaging
Pavlopoulos Elias Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Peltzer Nieves Linear ubiquitination protects from liver disease in response to obesity
Linear ubiquitination prevents MASLD by preserving adipose tissue integrity during obesity
Pérez-Guasch Martina Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Perucchini Chiara vascular control of MASH progression
Piper Hanley Karen Multiomic analyses demonstrate hepatocyte SOX9 loss exacerbates fibrosis and HCC development in the DEN-CCl4 mouse model
Portoles-Plaza Irene Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
Prognostic and Mechanistic Role of the cGAS-STING Pathway in Hepatocellular Carcinoma Pathogenesis
Pose Elisa Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Poso Antti PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Quince Megan Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
Rackham Owen Applying machine learning to identify modulators of immune cell function for targeted therapy in hepatocellular carcinoma
Ramon Gil Erik Platelets hijack neutrophils for pro-tumour polarisation in MASH-HCC
The ontogeny and therapeutic targeting of immunosuppressive neutrophils in hepatocellular carcinoma.
Ramon-Gil Erik Therapeutic targeting of cancer associated fibroblasts may allow for microenvironmental remodelling of immunotherapy resistant hepatocellular carcinoma
Randic Tijana Epigenetic Disordering by UHRF1 overexpression Drives Stemness and Senescence Escape in HCC
Ratz Michael In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Ravà Micol vascular control of MASH progression
Rebouissou Sandra Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
Reichow Marcel Embryonic Liver Innervation Regulates Glucose Metabolism and Contributes to Alagille Syndrome Defects
Reiner Juliander PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Rezvani Milad Combined stem cell and predictive models reveal flavin cofactors as targets in metabolic liver dysfunction
Rieger Vincent ECM1 as Tumor Suppressor in Hepatocellular Carcinoma through Inhibition of the Integrin-FAK-YAP axis
Rill Aina Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Rist Elke PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Rodefeld Julian Linear ubiquitination protects from liver disease in response to obesity
Linear ubiquitination prevents MASLD by preserving adipose tissue integrity during obesity
Ronco4 María Teresa Protective role of COX-2 expression in hepatocytes during obstructive cholestasis and intrahepatic cholestasis of pregnancy
Rost Fabian Understanding mechanisms of biliary fibrosis using periportal liver assembloids
Rubio Ana Belén Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Rudalska Ramona Pharmaceutical Development and Individual Case Studies for Skepinone-L, a Highly Potent and Selective p38a Inhibitor for the treatment of Advanced Hepatocellular Carcinoma
Sadler Kirsten Epigenetic rewiring of hepatocytes by Eed loss changes hepatocyte identity, liver damage, and fibrosis
Epigenetic Disordering by UHRF1 overexpression Drives Stemness and Senescence Escape in HCC
Salmon Hunter Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Sampaziotis Fotios TBA - Fotios Sampaziotis
Sanchez Alvarez Rosa Multiomic analyses demonstrate hepatocyte SOX9 loss exacerbates fibrosis and HCC development in the DEN-CCl4 mouse model
Sancho-Bru Pau Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Sanghvi Viraj TBA - Viraj Sanghvi
Sansores-Garcia Leticia Combining RAS and TEAD inhibitors eliminates cholangiocarcinoma
Schuette Svenja PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Schwab Matthias PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Schwabe Robert Targeting tumor-stroma crosstalk in cholangiocarcinoma
Schwartz Robert TBA - Robert Schwartz
Seehawer Marco PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Semsch Bettina Embryonic Liver Innervation Regulates Glucose Metabolism and Contributes to Alagille Syndrome Defects
Shavlakadze Tea Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Simpson Kara Multiomic analyses demonstrate hepatocyte SOX9 loss exacerbates fibrosis and HCC development in the DEN-CCl4 mouse model
Skalka George Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
Skliarenko Yuliia PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Sljukic Aleksandra Building Architecture and Complexity in Tissue-Derived Liver Organoids
Understanding mechanisms of biliary fibrosis using periportal liver assembloids
Sonanini Dominik PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Soria Anna Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Sun Jia In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Suzuki Toshiyasu Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
Tacke Frank Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Takebe Takenori TBA - Takenori Takebe
Tang Shifang Genomic insights into FGF21-mediated therapeutic effects in MASLD from 396 patient liver biopsies
Tchorz Jan Dynamic cell heterogeneity in homeostasis and chronic liver disease
Thomas Danis Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
Tong Chenhao TGF-β serves as a critical signaling determinant of liver progenitor cell fate and function
ECM1 as Tumor Suppressor in Hepatocellular Carcinoma through Inhibition of the Integrin-FAK-YAP axis
Regulation of essential hepatocyte functions and identity by super-enhancers in health and disease
Tonoian Robert In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Treinish Jacob Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Trompak Omelyan PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Tsiatouras Athanasios Spatiotemporal Quantification of Disease Biomarkers in the MASLD Spectrum Using Longitudinal Micro-CT Imaging
van Huffel Leen Combining RAS and TEAD inhibitors eliminates cholangiocarcinoma
Van Hul Noemi In utero next-generation single-cell lineage tracing reveals hepatic mesenchymal cell lineages
Embryonic Liver Innervation Regulates Glucose Metabolism and Contributes to Alagille Syndrome Defects
Van Vliet Saskia Embryonic Liver Innervation Regulates Glucose Metabolism and Contributes to Alagille Syndrome Defects
Vazquez Salgado Alexandra NEURL1B is required for mitotic spindle organization during liver regeneration and tumorigenesis
Veli Önay Linear ubiquitination protects from liver disease in response to obesity
Velliou Rallia-Iliana Spatiotemporal Quantification of Disease Biomarkers in the MASLD Spectrum Using Longitudinal Micro-CT Imaging
Verboven Elisabeth Embryonic Liver Innervation Regulates Glucose Metabolism and Contributes to Alagille Syndrome Defects
Vicente-Mora Javier Identification of Serum Amyloid A-expressing hepatocyte populations as new acute inflammatory driver in alcohol-associated hepatitis
Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Vidal Josep Perivascular macrophages increase in adipose tissue during metabolic dysfunction-associated fatty liver disease and contribute to local angiogenesis
Wagner Benedikt PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Wakai Matthew Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Wang Gengchao The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
TGF-β serves as a critical signaling determinant of liver progenitor cell fate and function
ECM1 as Tumor Suppressor in Hepatocellular Carcinoma through Inhibition of the Integrin-FAK-YAP axis
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Wangensteen Kirk NEURL1B is required for mitotic spindle organization during liver regeneration and tumorigenesis
Loss of BRCA2 Sensitizes Hepatocellular Carcinoma to PARP Inhibition with Olaparib
Wei Yi Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Weigelin Bettina PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Weihs Julian Combined stem cell and predictive models reveal flavin cofactors as targets in metabolic liver dysfunction
Weinberg Jaclyn Lactococcus lactis subspecies cremoris, mitigates metabolic disease and induces hepatoprotection by driving changes in the metabolome between the gut and liver.
Weng Honglei Regulation of essential hepatocyte functions and identity by super-enhancers in health and disease
TGF-β serves as a critical signaling determinant of liver progenitor cell fate and function
ECM1 as Tumor Suppressor in Hepatocellular Carcinoma through Inhibition of the Integrin-FAK-YAP axis
Wong    Chun-Ming The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Identifying hepatocellular carcinoma immunotherapy targets using population-level clinical data
Wu Mengjie The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Charting single-cell metabolism co-evolution during liver metastasis
Xiong Kun Transcriptomic signatures of rodent liver aging reveal increased infiltration of specific subsets of immune cells
Xu Wentao Regulation of essential hepatocyte functions and identity by super-enhancers in health and disease
Yakubovsky Oran A spatial transcriptomics atlas of live donors reveals unique zonation patterns in the healthy human liver
Yang Haochen Understanding mechanisms of biliary fibrosis using periportal liver assembloids
Yao Ye ECM1 as Tumor Suppressor in Hepatocellular Carcinoma through Inhibition of the Integrin-FAK-YAP axis
Yasaka Tyler Deep Learning–Driven HCC Morphologic Index from H&E Predicts Survival and Reveals Distinct Clinical and Molecular Phenotypes
Ectopic Wnt/β-Catenin Signaling Drives Cyclin-D1 Expression During Early Liver Regeneration
Yin Dingzi NEURL1B is required for mitotic spindle organization during liver regeneration and tumorigenesis
Loss of BRCA2 Sensitizes Hepatocellular Carcinoma to PARP Inhibition with Olaparib
Yin Swe Kyi Lai Spatial-temporal analysis of human-correlated genetically engineered mouse models reveals extensive heterogeneity of hepatocellular carcinoma that is associated with genetic drivers and exacerbated by a high fat diet
Zender Lars Pharmaceutical Development and Individual Case Studies for Skepinone-L, a Highly Potent and Selective p38a Inhibitor for the treatment of Advanced Hepatocellular Carcinoma
TBA - Lars Zender
PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer
Zerial Marino Understanding mechanisms of biliary fibrosis using periportal liver assembloids
Zhang Misty Shuo The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
The Mevalonate Pathway Orchestrates CoQ10 and Selenoprotein Translation to Promote Ferroptosis Resistance and Tumor Progression in HCC
Zhao Jieling A Digital Twin Model Reveals Mechanisms of Liver Fibrosis Patterning
Zhu Hao Identifying hepatocellular carcinoma immunotherapy targets using population-level clinical data
Zinngrebe Julia Linear ubiquitination prevents MASLD by preserving adipose tissue integrity during obesity
Zoppolato Elena The role of the liver microenvironment in Ras driven tumorigenesis
Zou Huihui ECM1 as Tumor Suppressor in Hepatocellular Carcinoma through Inhibition of the Integrin-FAK-YAP axis
Zucman-Rossi Jessica TBA - Jessica Zucman-Rossi
Prognostic and Mechanistic Role of the cGAS-STING Pathway in Hepatocellular Carcinoma Pathogenesis
Zucman-Rosssi Jessica Replication Stress Stratifies HCC Aggressiveness and Predicts ATR Inhibitor Sensitivity
Zwirner Stefan PhenoForge: Phenotype-driven forging of optimized small molecule-based compounds to target mitosis in cancer