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GENERAL INFORMATION Accommodations The conference participants will be staying at the Aldemar: Knossos Royal Village (A' class), which is
located in Hersonissos, 25 km from the airport. Breakfast
Breakfast will be
served at your hotel during the hours scheduled in this program. Conference
Venue The Aldemar: Knossos Royal Village Conference Center is
located at the hotel. Oral
Presentations An LCD projector
and an overhead projector will be available for the oral presentations. Speakers are asked to bring their USB flash drive
or CD to the conference reception desk at least 30 minutes prior to the
session. The allocated time for all
presentations, unless otherwise indicated, includes five minutes Q&A. Posters Posters
should be mounted Monday morning, May 29, on the designated boards and
dismounted at the end of the meeting. The dimensions of the boards are 90W x
150H cm. Adhesive tape for mounting the posters on the boards will be
available at the poster area. Welcome
Reception and Banquet Badges are required
for admission. Tour to Busses for the island tour will be leaving from the
hotel on Tuesday, May 30 at 2:30 p.m. Accompanying persons will also be
picked up at the hotel front lobby at that time. Badges are required
for participation. Lunches Lunches will be served at the indicated times to all
registered participants and registered accompanying persons in the hotel. Badges are required for admission.
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Sunday, May 28 |
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5:00 - 8:00 PM |
Open Registration |
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8:00 PM |
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Welcome Reception/Dinner |
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Monday, May 29 |
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8:30 AM |
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Welcome and Opening Remarks
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Session
I. |
Transcription Factors and Signals for
the Osteoimmune System: Part 1 |
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9:00 AM |
1 |
Control of cell migration by RANKL J Penninger |
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9:30 AM |
2 |
Schnurri-3: a key regulator of postnatal skeletal remodeling DC Jones, M Wein, and LH
Glimcher |
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10:00 AM |
3 |
Regulation of ectodomain shedding of
RANKL S Tanaka, A Hikita,
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10:30 AM |
4 |
Regulation of Osteoclast
Differentiation and Maturation Y Choi |
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11:00 AM |
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Coffee Break & Poster Session |
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Session
II |
Transcription
Factors and Signals for Osteoclasts |
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11:30 AM |
5 |
Molecular and cellular pathways in modeled arthritis |
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12:00 Noon |
6 |
Tumor necrosis factor and the osteoclast |
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12:30 PM |
7 |
Conditional mutagenesis reveals that nfatc1 is required for osteoclast
differentiation in vivo AO
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12:45 PM |
8 |
The
inositol polyphosphate 4-phosphatase type II, a
novel modulator of osteoclast differentiation
J Vacher, M Ferron, and M Pata |
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1:00 PM |
9 |
ID Helix-loop-helix proteins negatively regulate trance-mediated
osteoclasts differentiation N Kim, J
Lee, K Kim, JH Kim, H Mi Jin, HK Choi, SH Lee, Y
Yokota, SY Lee, and Y Choi |
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1:15 PM |
10 |
Osteoclastgenesis is regulated by cyclin-dependent
kinase 4/6 Y
Murakami, H Takayanagi, |
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1:30 PM |
11 |
Signaling
pathways mediated by the G protein subunit Gsa are involved in regulation of B lymphopoiesis
by osteoblasts JY
Wu, LE Purton, |
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1:45 PM |
12 |
Osteoblasts express members of the NOD family of intracellular
pattern recognition receptors that could mediate cell death and inflammation
associated with osteomyelitis I
Marriott |
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2:00 PM |
13 |
Cooperative
regulation of bone formation by NFAT and Osterix T Koga, K Nakashima, and
H Takayanagi |
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2:15 PM |
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Lunch |
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8:00 PM |
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Dinner at a Local Greek Tavern |
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The bus for the tavern will depart from the hotel at
7:30 PM |
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Tuesday, May 30
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Session
III |
Bone Metabolism, Hematopoiesis
and Immune responses |
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9:00 AM |
14 |
Immunologic
Regulation of Bone Cell Development M
Horowitz |
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9:30 AM |
15 |
PTH signaling and hematopoiesis H Kronenberg |
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10:00 AM |
16 |
Regulation of Hematopoietic Stem Cells
in the Osteoblastic Niche F
Arai |
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10:30 AM |
17 |
The
chemokine CXCL12 and regulation of HSC and B
lymphocyte development in the bone marrow niche T
Nagasawa |
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11:00 AM |
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Coffee Break, Poster Viewing, and
Poster Award Selection |
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1:30 PM |
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Lunch |
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2:30 PM |
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Tour to Knossos Archaeological site
& Archaeological Museum of Heraklion |
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The bus for the museum
will depart from the hotel at 2:30 PM |
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Dinner at a local Greek Tavern |
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Wednesday, May 31 |
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Session
IV |
Cytokines regulating the crosstalk
between bone and the immune system |
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9:00 AM |
18 |
Identification
of osteoclast precursor cells and the role of osteoclasts in anabolic responses to parathyroid hormone J Lorenzo |
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9:30 AM |
19 |
Inhibition
of osteoclastogenesis by interleukins, lectins and lymphocytes M
Gillespie |
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10:00 AM |
20 |
Interaction with estrogen receptors as treatment of arthritis
and osteoporosis H Carlsten |
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10:30 AM |
21 |
Functions of AP-1(Fos/Jun)in
inflammatory diseases E Wagner |
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11:00 AM |
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Coffee Break |
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Session
V |
Costimulation
in the immune system and bone |
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11:30 AM |
22 |
Novel signaling pathways and therapeutic targets in osteoclasts H Takayanagi |
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12:00 Noon |
23 |
TREM
receptors in osteoimmunology M Colona |
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12:30 PM |
24 |
Ligands
for TREM2, a regulator of osteoclastogenesis, are
expressed on both macrophages and preosteoclasts MC
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12:45 PM |
25 |
An immunoreceptor-like
pathway in neutrophils, macrophages and osteoclasts A Mocsai, MB Humphrey,
CL Abram, Z Jakus , Z Kertesz,
LL Lanier, MC Nakamura, and CA Lowell |
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1:00 PM |
26 |
NK
cells express RANKL and support osteoclast
formation in vitro S Owen, L Danks, M Feldmann, F Brennan, and NJ Horwood |
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1:15 PM |
27 |
CD4+
T cells induction of bone destruction during inflammation requires TNFa and not RANKL and is antagonized by IFNg acting in a STAT-1 independent manner via T-bet MP
Quinones, C Estrada, F Jimenez, HG Martinez, M Dudley, OW, RL |
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1:30 PM |
28 |
B-Lymphocytes
are not required for estrogen-mediated effects on bone mineral density M
Lindberg, C Jochems, A Kallkopf,
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1:40 PM |
29 |
ALPHA/BETA-T cells do not
modulate estrogen deficiency-induced bone loss in rats RG Erben and K Mildner |
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1:50 PM |
30 |
The inhibitor of T cell costimulation
CTLA-4IG prevents the loss of trabecular and
cortical bone loss induced by ovariectomy. Evidence
that T-cell activation is required for overiectomy
to induce bone loss F
Grassi, Y Gao, M
Terauchi, M Ryan, K Page, X Yang, |
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2:00 PM |
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Discussion for Abstract #28, 29, 30 |
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2:10 PM |
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Lunch |
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8:00 PM |
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Dinner at
Knossos Royal Village |
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Thursday, June 1 |
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Session
VI |
Factors regulating the crosstalk between
bone and the immune system |
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9:00 AM |
31 |
Regulation
of osteoclastogenesis by inflammatory cytokines and
SOCS A
Yoshimura, Y Minoda, H Takaki,
and M Ohishi |
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9:30 AM |
32 |
Role
of IKK subunits in osteoclast function and
inflammation-induced bone loss M Karin |
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Session
VII |
Osteoimmune
diseases |
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10:00 AM |
33 |
The role of cell-matrix interactions in osteoclast
differentiation and activation |
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10:30 AM |
34 |
Molecular
mechanisms of solid tumor metastases to bone T Guise |
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11:00 AM |
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Coffee Break |
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Session
VIII |
Novel Therapies |
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11:30 PM |
35 |
Targeting
osteoporosis, inflammation and bone resorption by
vaccination against cytokines MF
Bachmann, G |
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12:00 Noon |
36 |
RANKL
Inhibition: From Mice to Men (and Women) D Zack |
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12:30 PM |
37 |
Apoptotic Osteocytes Induce the
Production of pro-inflammatory osteoclastogenic
cytokines G Kogianni, V Mann, and BS
Noble |
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12:45 PM |
38 |
Hyaluronic acid inhibits osteoclast differentiation through toll-like receptor 4 HJ
Kim, EJ Chang, J Ha, HJ Kim, J Ryu, UH Kim, ZH Lee,
HM Kim, DE Fisher, and HH Kim |
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1:00 PM |
39 |
Altered osteogenic properties of bone marrow
stromal cells from multiple myeloma
patients G Brunetti, S Colucci, G Mori, A Oranger, R Rizzi, S Capalbo, V Liso, and
M Grano |
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1:15 PM |
40 |
Novel human RANKL mRNAS
are expressed in cell types associated with inflammatory bone loss NC |
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1:30 PM |
41 |
Shwachman-Diamond syndrome is associated with neutropenia and low-turnover primary osteoporosis | |