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General
Information
Accommodations
All
participants will be staying in the Santorini Image Hotel (A' class), which is located in Messaria, which is
a short distance from Fira and 3 km from the airport.
.
Workshop venue
The Nomikos Conference Center is located in Fira,
the capital of Santorini, overlooking the Caldera and the Santorini volcano.
Oral Presentations
An LCD projector, a projector for 2x2 inches slides and an
overhead projector will be available for the oral presentations. Speakers are asked to bring their slides to the
slide reception desk at least 30 min. before the beginning of the session.
Posters
Posters should be mounted
on the designated boards and dismounted according to the schedule below.
Adhesive tape for mounting
the posters on the boards will be available at the poster area.
Welcome Reception and Banquet
Invitation cards are required for admission.
City Tour
Buses for the city tour
will be leaving from the Nomikos Center on Saturday, October 13 at 2:45 p.m.
The accompanying persons maybe picked up at the Nomikos Center or otherwise
at the Santorini Image Hotel. Tickets are required for participation.
Tour and Travel Information
A desk manned by the personnel of our official
Travel Agency, “ERA Ltd” 8 Alexandrou Soutsou Str.,
Kolonaki 10671 Athens – Greece
Tel.: 30-1-363-4944,
FAX: 30-1-3631690, E-Mail: info@era.gr
will be located at the Nomikos Center and Santorini
Image Hotel throughout the Workshop.
Lunches
Lunches will be served at the indicated times to all
registered participants in the Nomikos Center. Badges are required for
admission
Program OUTLINE
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Wednesday, October 10
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Registration
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5:00-8:00
PM
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“Santorini
Image Hotel”
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Welcome
Reception
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8:00
PM
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“Santorini
Image Hotel”
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Thursday, October 11
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Breakfast
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7:30 AM
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“Santorini
Image Hotel”
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The bus will
depart from the “Santorini Image Hotel” at 8:30 AM
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Registration
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Nomikos
Center
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Session I: Structure-Functions
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Nomikos
Center
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Coffee
break
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11:00
AM
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Nomikos
Center
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Session II: The Central Nervous System
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11:30
AM
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Nomikos
Center
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Lunch
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1:30
PM
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Nomikos
Center
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Dinner
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8:00
PM
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“Pyrgos”,
Pyrgos
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The bus will depart from the
“Santorini Image Hotel” at 7:30 PM
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Friday, October 12
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Breakfast
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7:30 AM
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“Santorini
Image Hotel
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The bus will
depart from the “Santorini Image Hotel” at 8:30 AM
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Session III: Therapeutic Approaches
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9:00
AM
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Nomikos
Center
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Coffee
break
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11:00
AM
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Nomikos
Center
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Session IV: Therapeutic Approaches
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11:30AM
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Nomikos
Center
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Lunch
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1:15
PM
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Nomikos
Center
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Dinner
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8:00
PM
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“Selene”,
Fira
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The bus will depart from the
“Santorini Image Hotel” at 7:30 PM
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Saturday, October 13
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Breakfast
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7:30 AM
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“Santorini
Image Hotel”
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The bus will
depart from the “Santorini Image Hotel” at 8:30 AM
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Session V: Infectious Diseases
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9:00
AM
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Nomikos
Center
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Coffee
break
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10:20
AM
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Nomikos
Center
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Session VI: Allergic Reactions
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10:50
AM
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Nomikos
Center
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Poster Session
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12:10
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Lunch
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1:30
PM
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Nomikos
Center
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City
Tour
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2:45
PM
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Sunday, October 14
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Breakfast
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7:30 AM
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“Santorini
Image Hotel”
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The bus will
depart from the “Santorini Image Hotel” at 8:30 AM
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Session VII: Autoimmune Diseases and Pathophysiology
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9:00
AM
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Nomikos
Center
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Coffee
break
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11:00
AM
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Nomikos
Center
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Session VIII: Autoimmune Diseases and Pathophysiology
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11:30
AM
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Nomikos
Center
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Lunch
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1:30
PM
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Nomikos
Center
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Gala
Dinner
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8:00
PM
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Nomikos
Center
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The bus will depart from the
“Santorini Image Hotel” at 7:30 PM
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Monday, October 15
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Breakfast
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7:30 AM
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“Santorini
Image Hotel”
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Departure
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PROGRAM
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Wednesday, October
10
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5:00 PM – 8:00 PM
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Open Registration – “Santorini Image Hotel”
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8:00 PM
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Welcome Reception – “Santorini Iamge Hotel”
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Thursday, October 11
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7:30 AM
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Breakfast
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The bus will depart from the “Santorini Image Hotel” at 8:30 AM
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8:30 AM – 2:00 PM
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Registration – Nomikos Center
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Session I: Structure - Functions
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Co-chairs: Behrane
Ghebrehiwet, SUNY at Stony Brook
C. Yung
Yu, The Ohio
State University
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9:00 AM
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1
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Sructural requirements and
functional effects of the polymerization of C4b-binding protein
L Kask, B Dahlbäck, and AM Blom
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9:20 AM
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2
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C4b-binding protein binds to
the surface of apoptotic cells through anti-coagulant protein S
J H Webb, AM Blom, and B Dahlbäck
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9:40 AM
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3
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Characterization of
parameters influencing the enhancement of phagocytosis by C1qRP
AJ Tenner, S Ruiz, and M Park
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10:00 AM
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4
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The role of complement in
developmental processes
JD Lambris, K Del Rio-Tsonis, S
Francini, Y Kimura, M Majka, M Markiewski, D Mastellos, MZ Ratajczak, R
Reca, C Strey, and PA Tsonis.
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10:20 AM
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5
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Transcriptional regulation of
the human complement receptor 2 gene
GC Tsokos, M Tolnay, and LA
Vereshchagina
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10:40 AM
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6
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Difference in the intrinsic
strength of the human complement system: a study of C4a and C4b gene dosage
variations in three populations
CY Yu, Y Yang, CA Blanchong, B
Zhou, EK Chung, CM Bailey, K Jones, R Rennebohm, G Higgins, M Kovács, I
Karádi, L Varga, and G Fust.
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11:00 AM
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Coffee Break
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Session II: The central
nervous system
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Co Chairs: Andrea J. Tenner,
University of California, Irvine
Tony
Wyss-Corey, University of California San Francisco
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11:30 AM
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7
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Genetic inhibition of the
complement cascade increases Alzheimer’s pathology in transgenic mice
T Wyss-Coray, AH Lin, F Yan, JJ
Alexander, E Masliah, and RJ Quigg.
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11:50 AM
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8
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Complement is not essential
for the development of neuritic (senile) plaques in an animal model of
Alzheimer's disease
NR Cooper, BM Bradt, K Hsiao, MC
Carroll, and JX Yu
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12:10 PM
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9
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Activities of C1q in
Alzheimer's disease
AJ Tenner, MD Galvan, M Botto, and
MI Fonseca
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12:30 PM
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10
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Co-stimulatory effects of amyloid
ß-associated proteins C1q and SAP on the Aß1-42peptide-induced cytokine
synthesis by adult human microglia in vitro
R Veerhuis and P Eikelenboom
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12:50 PM
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11
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The role of complement in
acute traumatic injury of the brain
Z Fabry, B Nazewicz, F Liu, D
Sewell, JD Lambris, and M Sandor
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1:10 PM
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12
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The role of the complement
system in a mouse model of stroke
A-K Nilsson, MA Hietala, M Pekny,
and M Pekna
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1:30 PM
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Lunch
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8:00 PM
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Dinner at the Restaurant
“Pyrgos”, Pyrgos
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The bus will depart from
the “Santorini Image Hotel” at 7:30 PM
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Friday, October 12
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7:30
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Breakfast
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The bus will depart
from the “Santorini Image Hotel” at 8:30 AM
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Session III: Therapeutic
Approaches
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Co-chairs: Tom Eirik Mollnes,
University of Tromsř
Francesco
Tedesco, Trieste University
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9:00 AM
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13
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The primary role of
complement in the inflammatory network
TE Mollnes
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9:20 AM
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14
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A new C5a receptor antagonist
inhibits monoarticular arthritis in the rat
TM Woodruff, IA Shiels, DP Fairlie,
and SM Taylor.
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9:40 AM
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15
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CRP-mediated activation of
complement in acute myocardial infarction: a novel target for therapy?
CE Hack, R Nijmeijer, WK Lagrand,WT
Hermens, P Bruins, and HWM Niessen
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10:00 AM
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16
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Rational design of a
complement inhibitor targeting C3
D Morikis, AM. Soulika, M Roy, A
Sahu, A Troganis, PA Jennings, G Tsokos, and JD Lambris
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10:20 AM
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17
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Inhibition of C5 activation by
a SCFV obtained from human phage antibody library: in vitro and in vivo
effects
F Tedesco, R Marzari, P Macor, D
Sblattero, F Fischetti, and A Bradbury
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10:40 AM
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18
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Cancer treatment by
photodynamic therapy engages complement in tumor tissue destruction
M Korbelik, I Cecic, and J Sun
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11:00
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Coffee Break
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Session IV: Therapeutic
Approaches
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Co-chairs: Erik Hack, Central
Laboratory of The Netherlands Red Cross
Peter
A. Ward, University of Michigan
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11:30 AM
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19
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C5a in inflammatory
responses: just right or too much?
PA Ward, MS Huber-Lang, N
Reidemann, L Spruce, D Mastellos, and JD Lambris
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11:50 AM
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20
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C5a is responsible for the
mesenteric ischemia /reperfusion-induced local and remote organ injury
SD Fleming, JD Lambris, T
Shea-Donohue and GC Tsokos
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12:10 PM
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21
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Prevention of
ischemia/reperfusion injuries in rats by a new small molecule C5a receptor
antagonist
TV Arumugum, IA Shiels, DP Fairlie,
and SM Taylor
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12:30 PM
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22
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C1-inhibitor reduces the
ischemia-reperfusion injury of skeletal muscle in Balb-c mice after aortic
cross clamping
EW Nielsen , TE. Mollnes , JM.
Harlan, and RK Winn
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12:50 PM
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23
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Hereditary angioneurotic
edema in children
G Harmat, L Varga, G Füst , B
Fekete, I Karádi, B Visy, and H Farkas
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1:15 PM
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Lunch
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8:00 PM
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Dinner at Restaurant
“Selene”, Fira
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The bus will depart
from the “Santorini Image Hotel” at 7:30 PM
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Saturday, October 13
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7:30 AM
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Breakfast
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The bus will depart
from the “Santorini Image Hotel” at 8:30 AM
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Session V: Infectious
Diseases
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Co-chairs: Anna M. Blom, Lund
University
Matyas
Sandor, University of Wisconsin
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9:00 AM
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24
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Complement binding to S.
Aureus
KM Cunnion, JC Lee, and MM Frank
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9:20 AM
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25
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gC1qR/p33: a possible binding
site for extracellular HIV-1 TAT protein
B. Ghebrehiwet, M. Dalzell, B. Craddock,
SL Morrison, and R Steigbigel
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9:40 AM
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26
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A novel interaction between
type IV pili of Neisseria gonorrhoeae and the human complement regulator
C4b-binding protein
AM Blom, A Rytkönen, P Vasquez, G
Lindahl, B Dahlbäck, and A-B. Jonsson
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10:00 AM
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27
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C3 contributes to the
lethality of cerebral LCMV infection
M Sandor, D Sewell, Z Fabry, M.
Salvato, J.Lambris, and M. Suresh
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10:20 AM
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Coffee Break
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Session VI: Allergic Reaction
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Co-chairs: Joerg Köhl, Institute for Medical Microbiology
Rick
A. Wetsel, University of Texas-Houston
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10:50 AM
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28
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The absence of C3
demonstrates a role for complement in Th2 effector functions in a murine
model of asthma
SM Drouin, DB Corry, J Kildsgaard, and
RA Wetsel
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11:10 AM
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29
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Mast cells mediate the
inflammatory response in immune complex peritonits independent of TNF-a and
KC
J Godau, T Heller, A Kola , A Klos,
and J Köhl
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11:30 AM
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30
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C5a initiates the onset of contact
hypersensitivity in mice
H Hawlisch, T Heller, A Klos, and J
Köhl
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11:50 AM
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31
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In vitro testing and animal
models for complement activation-related pseudoallergy caused by liposomal
and micellar anticancer drugs
J Szebeni, L Baranyi, Y Barenholz,
Y Talmon, D Danino, S Savay, P Laverman, JM Metselaar, G Storm, R Bunger,
and CR Alving
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12:10 PM
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Poster session
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32
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Estimation of the complement
and cytokine levels in sera of patients with Guillain-Barre syndrome
A Ischenko, T Stuchevskaya, A
Zakhov, a Trofimov, S Rodin, A Simbirtsev, I Khajoueva, V Kazakov, and I
Rudenko
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33
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Expression and
Characterisation of the Serine Protease Domain of Human Complement C2
RC Priest, B McDowell, and R
Malhotra
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34
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GPI anchored erythrocyte CR1
deficiency in a rhesus monkey (Macaca mulatta)
A Kisserli, CD Muller, B Donvito, A
Gimenez, N Godin, M Tonye Libyh, V Duret, B Reveil, F Philbert, T Tabary, B
Hurtrel, and JHM Cohen
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35
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Indels within duplicated
genes have lead to sequence divergence: an examination of C2/Bf and C3/4/5
N Longman-Jacobsen, S Gaudieri, and
RL Dawkins
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36
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Effect of propranolol in vivo
and in vitro on oxidative burst of rat neutrophils and on complement
opsonizing capacity
EMS Russo-Carbolante, TS Marasca,
ACM Polizello, AECS Azzolini, and YM Lucisano-Valim
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37
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Anti-C1 esterase inhibitor
(C1-INH) autoantibodies in hereditary angioedema
L. Varga, G. Füst, B. Visy, and H.
Farkas
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38
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Helicobacter pylori infection
and hereditaty angioedema. New triggering factor?
H Farkas, G Füst, B Fekete, I
Karádi, B Visy, and L Varga
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39
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Effect of Hypothyroidism on
the Complement (C) System in the Rat
CG Duarte, AECS Azzolini, and AI
Assis-Pandochi
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40
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Proteomics-based analysis of
plasma proteins from patients with IFN-g and IL-12 receptor deficiency
B Tomaino, I Borghia, DA Lammasd, A
Zamperlinc, M Alessioc, and F Novellia
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41
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Increased frequency of C4B*Q0
in coronary disease: correlation with other known risk factors
GJ Arason, J Kramer, S Bodvarsson,
ST Sigurdarson, G Sigurdsson, G Füst, and G Thorgeirsson
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42
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Distribution of CR1
polymorphism in indian population
M Katyal and N Das
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43
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Experimental model to study
human skin and kelloid graft in hamster cheek pouch
B Hochman, LMFerreira, M Mariano,
and FV Boas
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44
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Effect of intravenous
immunoglobulin therapy on plasma complement levels in patients with SLE
Levy Y and Shoenfeld Y.
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45
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Oxidative stress and use of
DMSO in cultivated keratinocytes submitted to the glucose privation and
physic hypoxia
I da Silva Duarte, LM Ferreira, and
B Hochman
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46
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Complement Involvement in
RPE-Hypersensitivity
CE Thirkill, JL Keltner, and LS
Morse
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1:30 PM
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Lunch
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2:45 PM
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City Tour
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Sunday, October 14
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7:30
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Breakfast
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The bus will depart
from the “Santorini Image Hotel” at 8:30 AM
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Session VII: Autoimmune
Diseases and Pathophysiology
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Co-chairs: Michael M. Frank,
Duke University
Paul
Morgan, UWCM
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9:00 AM
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47
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The role of the membrane
complement regulatory Decay Accelerating Factor (DAF, CD55) in the MRL-LPR
murine model of systemic autoimmunity
T Miwa T, MA Maldonado, HY Luo, VP
Werth, MP Madaio, RA Eisenberg, and WC Song
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9:20 AM
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48
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Pathologic significance of
autoantibodies against C1q in the development of renal disease
LA Trouw, J Duijs, and MR Daha
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9:40 AM
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49
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IL-6, TNF and Complement in
Antibody Mediated Myasthenia Gravis Pathogenesis
P Christadoss, E Goluszko, C Deng,
H Yang, and M Poussin
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10:00 AM
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50
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Complement deficiency
ameliorates collagen-induced arthritis in mice
MA Hietala, S Kleinau, I-M Jonsson,
A Tarkowski, and M Pekna
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10:20 AM
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51
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A CR1 polymorphism exhibits
enhanced binding to C4b which may contribute tp protection against SLE in
caucasians
DJ Birmingham, W Chen, G Liang, and
HC Schmitt
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10:40 AM
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52
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Defective prevention of
immune precipitation in SLE is not caused by C4A*Q0
R Kolka, SR Franzdottir, ÁB
Hreidarsson, A Árnason, K Steinsson, and GJ Arason
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11:00 AM
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Coffee Break
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Session VIII: Autoimmune
Diseases and Pathophysiology
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Co-chairs: Zsuzsanna Fabry, University of Wisconsin
Wenchao
Song, University of Pennsylvania
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11:30 AM
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53
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The CD59-knockout mouse:
characterization of the phenotype and studies in complement-driven
experimental diseases
BP Morgan
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11:50 AM
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54
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CD59 knockout and CD59/DAF
double-knockout mouse eryrthrocytes are highly susceptible to induced but
not spontaneous complement damage
T Miwa, L Zhou, and WC Song
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12:10 PM
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55
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Complement activation at the
C3 level is anti-atherogenic in mice
L Persson, J Borén, GK Hansson, and
M Pekna
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12:30 PM
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56
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Complement C3, C4 and factor
B gene expression in human kidney tissue engrafted into SCID/RAT
J Laufer,R Oren,. B Dekel,.T
Burakova, Y Reisner, and J Passwell
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12:50 PM
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57
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Role of HLA-DQ and -DR genes
in human autoimmune diseases. Studies with transgenic/knockout mice
CS David
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1:10 PM
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58
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DNA vaccination to prevent
autoimmune diabetes
M von Herrath, A Hughes, T Wolfe,
and A Bot
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1:30 PM
|
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Lunch
|
|
|
|
|
|
8:00 PM
|
|
Gala Dinner
|
|
|
|
The bus will depart
from the “Santorini Image Hotel” at 7:30 PM
|
|