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GENERAL INFORMATION Accommodations The conference participants will be staying at the Minoa
Palace Hotel, which is located in Platanias, 24 km
from Chania International Airport and 12 km west of
Chania town center.
Participants are kindly asked to take a taxi from the airport to the
hotel (~25 EURO) Arrival and Check-in It is expected that attendees will
arrive/check-in on Sunday after 2:00 PM. Anyone arriving after 10:00 pm on
Sunday must make alternative dinner arrangements. Breakfast
Breakfast will be served at your
hotel during the hours scheduled in this program. Conference Venue The Oral Presentations An LCD projector and an overhead projector will be available for
the oral presentations.
Speakers are asked to bring their USB flash drive or CD to the
conference reception desk at least 30 minutes prior to the session. The allocated time for all presentations,
unless otherwise indicated, includes five minutes Q&A. Posters Posters should be mounted Sunday,
September 27, from 6:00 pm – 8:00 pm on the designated boards and dismounted at the end of the
meeting. The dimensions of the boards are 90 cm wide x 140 cm high. Adhesive
tape for mounting the posters on the boards will be available at the poster
area. Welcome Reception and Gala Dinner Badges are required
for admission. City Tour Busses for the city tour
will be leaving from the hotel on Wednesday,
September 30 at 3:00 pm Accompanying persons will also be picked up at the
hotel front lobby at that time. Badges
are required for participation. Lunches Lunches will be served
at the indicated times to all registered participants and registered
accompanying persons in the hotel. Badges
are required for admission. Dinners/Informal
Discussions Three dinners/informal discussion
will be served. Vegetarian entrees are available only if the request is made
in advance of the meeting. Internet, Phone,
& Computer Wireless Internet access is located throughout the conference center free charge during meeting hours. There are computers available in the hotel’s business center for the use of the attendees. Phone service is available for an additional charge from your hotel room. Other Information Animals are not permitted on site. All Aegean Conferences events are non-smoking. |
Sunday, September 27 |
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6:00 - 8:00 PM |
Open Registration |
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8:00 PM |
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Welcome
Reception/Dinner |
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Monday, September 28 |
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8:45 AM |
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Welcome and Opening Remarks
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Session
I |
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Innate
Immunity |
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Chairs: B Pulendran |
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9:00 AM |
1 |
Modulating vaccine responses with innate immunity B Pulendran |
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9:30 AM |
2 |
Dendritic cell subsets: priming and boosting CD8 T cell
immunity S Bedoui, PG Whitney, A Proietto,
L Wakim, J Waithman, G
Davey, I Caminschi, K Shortman, FR Carbone, AG
Brooks and WR Heath |
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10:00 AM |
3 |
The
Renaissance of Complement J Lambris |
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10:30 AM |
4 |
Peptides modulating conformational changes in
secreted chaperones: From in silico design to
preclinical proof of concept O Levy, Y Kliger, A Oren, H Ashkenazy, A Novik,
A Amir, A Wool, Z Levine, C |
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10:50 AM |
5 |
An
essential role of MyD88 signaling in dendritic
cells in the protective immunity to Toxoplasma gondii B Hou,
A Benson, L Kuzmich, A DeFranco,
and F Yarovinsky |
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11:10 AM |
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Coffee Break |
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Session
II |
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NK cells |
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Chairs: A Moretta |
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11:45 AM |
6 |
Keynote Lecture I: NK cells - bridging innate and
adaptive immunity LL Lanier |
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12:30 PM |
7 |
Specificity of Alloreactive
NK cells A Moretta |
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1:00 PM |
8 |
The bzip
transcription factor E4BP4/NFIL3 is critcaly
required for NK-Cell development DM Gascoyne, E Long, H Veiga-Fernandes,
J de Boer, O Williams, B Seddon, M Coles, D Kioussis, and
HJM Brady
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1:30 PM |
9 |
NK cell regulation of antiviral T cells
alters viral clearance and immune pathology SN Waggoner, RT |
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1:50 PM |
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Lunch/Disucussions |
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Session
III |
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NIH
sponsored session: Exploiting Innate Immunity in Early/Acute HIV infection to
Inform Vaccine Discovery and Design Chair: GP Bansal |
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3:30 PM |
10 |
Innate
immune responses in acute HIV-1 infection P Borrow, S
Brackenridge, O Dibben, D Goldstein, EA Haygreen, BF Haynes, BKessler,
H Kramer, KJ Lavender, AJ McMichael, PJ Norris, L Qin, AR Stacey, E Taylor, G
Bansal and the Centre for HIV and AIDS Vaccine Immunology (CHAVI) |
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3:50 PM |
11 |
Immunological
challenges in developing a vaccine against HIV DR Casimiro |
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4:15 PM |
12 |
Protective immunity: Lessons from elite
HIV controllers G Alter |
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4:40 PM |
13 |
Innate
immune responses in pathogenic versus non-pathogenic SIV infected nonhuman
primates AA Ansari, F Villinger, A Mayne, S Stephenson, Y Takahashi, D Little, I Dreith, and P Bostik |
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5:05 PM |
14 |
Can cross talk between adaptive and innate immune
responses exploit HIV's Achilles' heel? D Unutmaz |
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8:00 PM |
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Dinner / Informal Discussions at a local Greek Restaurant |
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The bus for the restaurant will depart from the
hotel at 7:30 PM |
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Tuesday, September 29
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Session
IV |
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CD4+ T cells |
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Chair: M Turner |
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9:00 AM |
15 |
Keynote
Lecture-II: Memory CD4 T Cells Induce an
Innate Inflammatory Response T
Strutt, KK McKinstry, and
SL Swain |
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9:45 AM |
16 |
pi3k
delta is essential for the function of T follicular helper cells M Turner, |
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10:15 AM |
17 |
Specialization of Regulatory T cell
Subsets via cytokine production by effector T cells MA Koch, NR Perdue, KS Smigiel, and DJ
Campbell |
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10:35 AM |
18 |
Intranasal vaccination with Proteosome-based adjuvants has
the unique ability to induce strong IL-23/IL-17 responses V Allard, M Plante, DS
Burt, and C Daniel |
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10:55 AM |
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Coffe Break &
Poster Session |
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Session
V |
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CD8+ T cells |
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Chair: |
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11:45 AM |
19 |
Generating
protective memory CD8 T cell responses NL Pham, L
Epping, C Fleenor, V Badovinac,
and J Harty |
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12:15 PM |
20 |
Molecular
determinants of CD8+ T cell memory S Feau, M Wolkers, R Arens, |
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12:45 PM |
21 |
CD8
effectors elicit multiple protective effects H Hamada and R
Dutton |
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1:15 PM |
22 |
Virtual
Memory CD8+ T cells: Adaptive Immunity's First Responders R Kedl |
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1:45 PM |
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Lunch/Disucussions |
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8:00 PM |
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Dinner / Informal Discussions at a Greek Restaurant |
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The bus for the restaurant will depart from the
hotel at 7:30 PM |
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Wednesday, September 30 |
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Session
VI |
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Molecular control of Immunity |
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Chair: PD Katsikis |
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9:00 AM |
23 |
Genetic and epigenetic regulation of adaptive immune
responses H Yoon, C David, R Ahmed, and JM Boss |
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9:30 AM |
24 |
Transcriptional
control of CD8 and NKT cell development and homeostasis LM D’Cruz, J Fujimoto, and AW Goldrath |
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10:00 AM |
25 |
Coordinate regulation of effector
and memory differentiation G Belz, A Xin, F Masson, S Nutt, and A Kallies |
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10:30 AM |
26 |
MicroRNA miR-155 regulation of CD8+ T cell responses PD Katsikis |
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11:00 AM |
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Coffee Break |
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Session
VII |
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B cells |
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Chairs: D Tarlinton |
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11:30 AM |
27 |
B cell survival strategies in establishing and maintaining
memory D Tarlinton |
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12:00 Noon |
28 |
The pro- and anti-inflammatory activity
of immunoglobulin G F Nimmerjahn |
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12:30 PM |
29 |
CD28 supports normal plasma cell
survival and interactions with the microenvironment CH Rozanski, R Arens,
J Nair, L Carlson, SP Schoenberger, and KP Lee |
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12:50 PM |
30 |
Structural
basis of the recognition of mouse Cd1d-a-Galactosylceramide by mouse Va14-vb8.2
and Va14-vb7
semi-invariant nkt t-cell receptors O Patel, DG Pellicci, L Nielsen, S Pang, LC
Sullivan, K Kyparissoudis, AG Brooks, HH Reid, S
Gras, I Lucet, R Koh, MJ
Smyth, T Mallevaey, JL Matsuda, L Gapin, J McCluskey, DI Godfrey,
and J Rossjohn |
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1:10 PM |
31 |
Protective
immune responses to novel swine-origin 2009 A (H1N1) Influenza virus I Skountzou, DG Koutsonanos, R Compans, and J Jacob |
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1:30 PM |
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Lunch/Disucussions |
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2:45 PM |
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City Tour |
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The bus for
the tour will depart from the hotel at 2:45
PM |
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8:00 PM |
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Dinner / Informal Discussions at a Greek Restaurant |
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Thursday, October 1 |
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Session
VIII |
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The role of APC |
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Chair: T Brocker |
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9:00 AM |
32 |
Cross-presentation
in steady-state and viral defense T Brocker |
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9:30 AM |
33 |
Functions
of blood monocytes F Geissmann |
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10:00
AM |
34 |
Lipid
links: Innate and adaptive immune responses shaped by TLR2 agonists Y Thanavala and
A Lugade |
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10:30 AM |
35 |
Early
innate reactions of dendritic cells to vaccines
correlate with the magnitude and phenotype of the immune response evoked by
vaccination A
Huckriede, J Pool, F Geeraedts, J de Vries-Idema, and J Wilschut |
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10:50
AM |
36 |
Cathepsin S regulates macrophage innate and adaptive immune
responses to mycobacterium X Wang, A Lau,
HS Kang, TY A Liao, JSun, A Talal,
and Z Hmama |
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11:10
AM |
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Coffee Break & Poster Session |
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Session
IX |
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Immunity to Infection |
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Chair: EJ Wherry |
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11:45 AM |
37 |
Transcriptional regulation of
CD8 T cell exhaustion during during chronic viral
infection H Shin,
SD Blackburn, AM Intlekofer, C Kao, JM Angelosanto, SL Reiner, and EJ Wherry |
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12:15 PM |
38 |
Tracking CD4 T cell responses to Salmonella |
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12:45 PM |
39 |
MYELOID Heme
oxygenase-1 regulates innate immunity and autoimmunity VIA modulation of the
IRF3 signaling pathway G Kollias |
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1:15 PM |
40 |
A role for the non-classical MHC class I
molecule HLA-E in the innate and adaptive immune response to human
cytomegalovirus LC Sullivan, G
Pietra, J Lin, SL Heatley, C Clements, T Beddoe, JB Jordan, HL Hoare, L Moretta,
J Rossjohn, and AG Brooks |
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1:35 PM |
41 |
Rapid and
prolonged presentation of a glycoprotein D epitope
to HSV-1 specific CD4+ T cells following flank-zosteriform
infection P Whitney, S Bedoui, G Davey, C Jones, F Carbone, P |
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1:50 PM |
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Closing
Remarks |
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2:00 PM |
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Lunch/Disucussions |
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8:00 PM |
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Farewell Dinner |
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Friday, October 2
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7:30 AM |
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Breakfast |
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Posters
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42 |
Increased
Tbet corresponds with increase in senescence marker
CD57 in influenza virus-specific CD8+ T cells in aged individuals DV
Dolfi, AM Polley, KE Schmader, and EJ Wherry |
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43 |
Characterization of age
related changes in Natural killer cell subsets during primary influenza
infection |
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44 |
Herpes simplex virus type
1 interferes with NKT cell activation L Bosnjak, M Moll, and
JK Sandberg |
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45 |
Targeting
dendritic subsets in vivo for vaccine enhancement
using novel surface receptors I
Caminschi, F Ahmet, AM Lew, WR Heath, K Shortman, and MH Lahoud |
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46 |
NK
regulatory cells inhibit autoreactive T cell
responses in rats by a nitric oxide-dependent mechanism T Kheradmand, NA Wolf,
and RH Swanborg |
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47 |
Naïve macrophages suppress
T cell proliferation via a nitric-oxide dependent mechanism MJ Hamilton, F Antignano,
A Von Rossum, B Luk, and G Krystal |
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48 |
Early immune system
response to infection: relationship to cerebral malaria NH Hunt, J Miu, A Mitchell, AM Hansen, L Hee,
SM Potter, and HJ Ball |
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49 |
Innate
and adaptive properties of the CD3+ CD56+ NKT cell response to HIV-1 KJ Lavender, |
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50 |
Adaptive
immunity is dispensable in primary Acinetobacter baumannii lung infection but enhances resistance to
secondary infection H
Qiu, R KuoLee, G Harris, and W Chen |
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51 |
EPL2, a novel
antibacterial peptide from Eisenia
fetida tissue defenses against E. coli
O157:H7 X
Liu, W Xing, Z Sun, and |
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52 |
Regulation of human monocytes/macrophages by helminth
parasites results in the induction of markers associated with alternative
activation of macrophages and affects the expansion of foxp3+ T cells RT Semnani, L Mahapatra,
V Sanprasert, P Goel, and
TB Nutman |
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53 |
Combined
TLR engagement in dendritic cells differentially
influences the outcome of dendritic cell activation
and antigen presentation S
Siddiqui and |
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54 |
Genomics
and proteomics analysis in immune responses of earthworm Eisenia fetida after exposure to cadmium X Wang, L Chang, Z Sun, an H Ma |
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55 |
Function of physical
antibiotic barrier of Eisenia fetida defenses against
E. coli O157:H7 X Liu, W Xing, Z Sun, and |
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56 |
A differential study of
the Caenorhabditis Elegans
proteome after infection with A Gram-negative or Gram-positive bacterium A Bogaerts, P Verleyen,
L Temmerman, E Meelkop, B
Boerjan, A Reumer, and L Schoofs
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57 |
Exploring the protective
effect of Drosophila PEBP1 in innate immunity A Reumer, A Bogaerts, T Van Loy, S Husson, L Temmerman, E Clynen, B Hassan, and L Schoofs |
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58 |
Immunomodulation of CD8 T cell quantity and phenotype by novel
vaccine adjuvants F Stark and L Krishnan |