PROGRAM
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Sunday, May 26 |
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5:00 – 8:00 PM |
Open Registration |
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8:00 PM |
Welcome Reception |
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Monday, May 27 |
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7:30 AM |
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Breakfast |
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8:00 AM-2:00 PM |
Registration |
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Session I: Complement Co-Chairs: Anna Erdei, Paul P. Morgan |
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9:00 AM |
1 |
Complement as the lynchpin of innate immune defence in
the central nervous system. B.P. Morgan and P. Gasque |
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9:25 AM |
2 |
Modulation of the adaptive immune response by innate elements. A. Erdei, Zs. Bajtay, J. Prechl, M. Józsi, K. Kerekes, E. Molnár |
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9:45 AM |
3 |
Complement activation and deflection of innate immunity
during sepsis. P.A. Ward, N. Riedemann, M. Huber-Lang, V. Sarma, J.D. Lambris,
and F. Zetoune. |
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10:05 AM |
4 |
Fibronectin is upregulated by the anaphylatoxin C5a in
hepatic stellate cells from rat liver. O. Götze, M. Schmitz and
G. Schlaf |
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10:25 AM |
5 |
L-Ficolin/P35 Associates to MASP-1, -2, -3 and MAp19 with
high affinity and competes with MBL. N. Thielens, S. Cseh, L. Vera, M. Matsushita, T Fujita & G.
Arlaud |
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10:45 AM |
6 |
Inhibition of tissue factor abrogates Instant Blood-Mediated
Islet Reaction (IBMIR) in vitro: Possible application in clinical allogeneic
pancreatic islet transplantation. B. Nilsson, L. Özmen, A. Lukinius, H. Johansson, G. Elgue, K. Nilsson
Ekdahl, O. Korsgren, |
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11:05 AM |
7 |
Rational design of a complement inhibitor targeting C3. D. Morikis, L. Spuce, C. Floudas, and J.D. Lambris |
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11:30 AM |
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Coffee Break |
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Session II: Development Co-chairs: Dimitrios
Mastellos, Billie J. Swalla |
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12:00 Noon |
8 |
A critical role for the complement C5a anaphylatoxin receptor
in liver regeneration D. Mastellos, M. Markiewski, C. W. Strey, R. Tudoran, L. Greenbaum
and J. D. Lambris |
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12:25 PM |
9 |
The role of a newly-identified heterologous crosstalk between
G-protein coupled seven transmemrbrane span receptors - chemokine receptor
CXCR4 and complement C3aR in human hemato-lymphopoiesis and innate immunity.
R. Reca, M. Majka, J. Kijowski, D. Mastellos,
S. Franchini, J.D. Lambris & M. Z. Ratajczak |
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12:45 PM |
10 |
Expression patterns of C3 and Bf genes during embryo development
in the Ascidian Ciona Intestinalis (Urochordata). P.R. Pinto, F. Yoshizaki, Y.
Kimura, R. Marino, R. De Santis, M. Nonaka, J.D. Lambris |
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1:05 PM |
11 |
The activation of the innate immune system during Ascidian
Metamorphosis B.J. Swalla and B.J. Davidson |
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1:30 PM |
12 |
Hemolin is an insect immune protein crucial for embryonic
development. R. Bettencourt, Y. Assefaw Redda, O. Terenius, and I. Faye |
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1:55 PM |
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Lunch |
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8:30 |
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Dinner at a local Greek
Taverna in Myconos Center The bus will depart from the “Royal Myconian Hotel”
at 6:00 pm |
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Tuesday, May 28 |
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7:30 AM |
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Breakfast |
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Session III: NK, Mast Cells, and DC Co-chairs: Doina Ganea,
Peter Parham |
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9:00 AM |
13 |
Interaction of human NK cells with tumor targets and with
other members of the innate immune response. A. Moretta |
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9:25 AM |
14 |
Co-evolution of NK Cell Receptors and MHC Class I. P. Parham |
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9:50 AM |
15 |
Role of Natural Killer Cells as Long-Term Viral Reservoir
And Sanctuary For HIV-1 In Patients. A. Valentin, M. Rosati, R. Yarchoan, G.N.
Pavlakis |
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10:15 AM |
16 |
Mast Cells as Sentinels and Effectors of Innate Immunity. S.J. Galli |
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10:40 AM |
17 |
Neuropeptides control cytokine and chemokine production
by dendritic cells. D. Ganea, E. Vassiliou, M. Delgado,
X. Jiang |
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11:05 AM |
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Coffee Break |
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11:30 AM |
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Poster Session |
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18 |
Gilthead seabream acidophilic granulocytes are active phagocytic
cells and produce IL-1b E. Chaves-Pozo, P. Pelegrin,
J. Garcia-Castillo, A. Tomas-Loba, A. Garcia-Ayala, V. Mulero, J. Meseguer |
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19 |
Expression and identification of leucocyte receptors mediating
innate cytotoxic activity in the Mediterranean gilthead seabream (Sparus
aurata L.) A. Cuesta, M.A. Esteban, J. Meseguer |
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20 |
Molecular cloning and expression analysis of TNF a from a marine fish
reveal its constitutive expression and ubiquitous nature. J. Garcia-Castillo, P. Pelegrin,
E. Chaves-Pozo, A. Tomas-Loba, V. Mulero, J. Meseguer |
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21 |
Genomic structure and expression analysis of two pleurocidin
gene clusters from the winter flounder, pleuronectes americanus. S. E. Douglas and J.W. Gallant |
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22 |
Structure and activation of the limulus amebocyte. M. Conrad, R. Pardy, N. Wainwright, A. Child, K. Lee, W. Cohen,
and P. Armstrong |
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23 |
Structure and activation of non-mammalian thrombocytes. K-G Lee, T. Miller, I. Anastassov, and W.D. Cohen |
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24 |
A pattern recognition receptor activates Imd/Relish-mediated
antibacterial defense and prophenoloxidase cascade in drosophila. S.Kurata |
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25 |
Antitumor activities of gaegurin 6 against wild-type and
multidrug resistant tumor cell. B.J. Lee, S. Kim, S.S. Kim, Y.-J. Bang, S-J. Kim |
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26 |
Identification and characterization of xenopus CD8+ T cells
that express a NK cell-associated molecule. J. Robert, .L Rau, T. Horton, J. Gantress, A. Bell, R. Stewart,
N. Cohen, & J. Horton |
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27 |
A peptidoglycan recognition protein with amidase activity.
P. Mellroth, J. Karlsson, H. Steiner,
H |
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28 |
Interaction of Ascorbic Acid with several genotoxic agents.
Studies using the wing spot test in Drosophila melanogaster. B. Kaya, A. Creus, A. Velázquez,
A. Yanikoglu and R. Marcos |
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29 |
Cytokine response to Streptococcus pneumoniae infection:
a bridge between innate and adaptive immune systems. Y. Mizrachi Nebenzahl E. Ling, N. Troyanovsky, G. Feldman, R. Dagan |
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30 |
S. Pneumoniae surface lectin and non-lectin proteins as
putative vaccine against mucosal and invasive diseases. Y. Mizrachi Nebenzahl., E. Ling, G. Feldman, S. Lifshitz, M. Portnoi,
K. Overweg, J. Wells, R. Dagan |
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31 |
CD59 Expression promotes EL4 tumor growth in syngeneic
C57BL/6 Mice. M. Imai, F. Hong, G.D. Ross, and S. Tomlinson |
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32 |
Functional dissection of ETS transcription factor MEF and
its synergistic upregulation of the lysozyme gene expression with KLF
family members, UKLF and LKLF. M. Suico, T. Koyanagi, S. Ise, Z. Lu, A. Hisatsune, Y. Seki, T.
Shuto, Y. Isohama, T. Miyata, H. Kai |
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33 |
Calnexin and ƒ´F508 CFTR are colocalized in the inclusion
body-like structures in the endoplasmic reticulum. T. Okiyoneda, K. Harada, K. Yamahira, T. Shuto, H. Kai. |
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34 |
ETS2 is involved in protein kinase C-activated expression
of granulocyte-macrophage colony-stimulating factor in human airway
epithelial cell line, A549. Z. Lu, K.A .Kim, M.A. Suico, A. Uto, Y. Seki, T. Shuto, Y. Isohama,
T. Miyata and H. Kai |
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35 |
Neuropeptides affect the expression and release of TH1/TH2-specific
chemokines in murine spleen cells. D. Ganea, X. Jiang. |
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36 |
Suppression of Hepatitis B Virus gene expression and replication
by IL-4. C. Hu, S.-J. Lin, C. Chang |
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37 |
Carp granulocytes in bacterial infection. T. Moritomo, H. Kodama, K. Tijiwa, and T. Nakanishi |
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38 |
CR2 units of CR2 complexes are possibly
associated through covalent links reactive with necleophilic agents.
G. Barile, M. Grazia Di Certo and A. Faggioni |
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1:30 PM |
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Lunch |
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Wednesday, May 29 |
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7:30 AM |
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Breakfast |
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8:30 AM–1:30 PM |
Delos Tours |
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1:30 PM |
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Lunch |
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Session IV: Evolution Co-chairs: John J. Marchalonis, Masaru Nonaka |
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5:00 PM |
39 |
Innate immunity and the primordial combinatorial repertoire.
J.J. Marchalonis |
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5:25 PM |
40 |
Evolution of the complement system from invertebrates to
vertebrates. M. Nonaka, S. Miyazawa, F. Yoshizaki, K. Endo |
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5:50 PM |
41 |
Molecular basis of non-self recognition by the horseshoe
crab tachylectins. S-I. Kawabata |
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6:15 PM |
42 |
Heat shock proteins: and evolutionary bridge between innate
and adaptive immunity. J. Robert, J. Gantress, A. Bell, G. Maniero,
N. Cohen & L. Rau |
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6:35 PM |
43 |
ATP Is involved in the secretion of mature fish IL-1beta Pelegrin P, Garcia-Castillo J,
Chaves-Pozo E, Tomas-Loba A, Mulero V and Meseguer J |
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6:50 PM |
44 |
A novel cathelicidin antimicrobial gene from the harbour
seal, phoca vitulina. G. McLaughlin and V.J. Smith |
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7:05-7:20 PM |
45 |
Scavenger receptor-like activity in rainbow trout kidney.
M.K. Frøystad, V. Volden, E.S
Bækkevold , T. Berg, and T. Gjøen |
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8:00 PM |
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Dinner |
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Thursday, May 30 |
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7:30 AM |
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Breakfast |
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Session V: Host-Pathogen Interactions Co-Chairs: Harvey H.
Friedman, Matyas Sandor |
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9:00 AM |
46 |
Complement immune evasion strategies of microorganisms.
H.M. Friedman, M. Jiang, K. Judson, Y. Chang, L. Hook,
X. Lin, J. Lubinski |
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9:25 AM |
47 |
C3 contributes to protection, pathology and T cell epitope
selection in the course of LCMV infection M. Sandor, D. Sewell, Z. Fabry, M. Salvato, J.D. Lambris, M. Suresh |
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9:50 AM |
48 |
Phosphoethanolamine substitutions on neisserial
lipooligosaccharide are the preferred acceptors for C4. P.A. Rice, A. Cox, R. Boden, E.R. Moxon, S. Meriý, U. Vogel and
S. Ram. |
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10:10 AM |
49 |
Interaction between microbial virulence factors and host
innate immune response determines Streptococcus pneumoniae disease outcome. Yaffa Mizrachi Nebenzahl, Sarit Lifshitz, Sara Novick, Rachel Teitelbaum,
Galina Feldman, Maxim Portnoi, Ron Dagan. |
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10:30 AM |
50 |
Reactive oxygen species-dependent pathway mediates the
activation of interferon regulatory Factor 3 by lipopolysaccharide.
L. Navarro, O. Dang and M. David |
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10:50 AM |
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Coffee Break |
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Session VI: Host-Pathogen Interactions Co-chairs: Bruce Beutler,
Bo Nilsson |
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11:30 AM |
51 |
A forward genetic approach to innate immune defense. B. Beutler |
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11:55 AM |
52 |
Staphylococcal toxin superantigens:
Understanding the mechanism of their action and engineering receptor
mimics to inhibit superantigen pathogenesis. E.
Hong-Geller, J. Smith, N. Lehnert, M. Möllhoff, P.R. Shiflett, P.E.
Pardington, R.B. Cary, and G. Gupta |
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11:15 PM |
53 |
Glucocorticoids synergistically enhance nontypeable haemophilus
influenzae-induced Toll-like Receptor 2 expression via a negative cross-talk
with p38 MAP kinase. T. Shuto, A. Imasato, H. Jono, A. Sakai, H Xu, T. Watanabe, D.R.
Rixter, H. Kai, A. Andalibi, F. Linthicum, Y.L. Guan, J. Han, A.C. Cato,
D.J. Lim, S. Akira and J.D. Li |
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12:35 PM |
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Toll-like receptors 2 and 4 are expressed in human keratinocytes.
A. Pivarcsi, B. Réthi, A. Kenderessy-Szabó, M. Széll, Zs. Beer,
Zs. Bata-Csörgõ, , M. Magócsi, É.
Rajnavölgyi, A. Dobozy, L. Kemény |
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12:55 PM |
55 |
Lipid mediators
and nitric oxide in control of innate response in pulmonary microcirculation.
S. Chlopicki, J.B. Bartus, M.Walski, R.J.
Gryglewski |
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1:15 PM |
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Evidence
for cathelicidin peptide-mediated induction of cell death and identification
of potential cathelicidin interactors in effector cells of immune response.
M.
Zanetti, A. Sgorbissa, R. Circo, L. Tomasinsig, B. Skerlavaj, A. Risso,
P. Bernardi |
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1:35 PM |
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Lunch |
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8:00 PM |
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Gala Dinner |
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